Projecten per jaar
Persoonlijk profiel
Expertise
I am an experienced scientist and project manager with hands on experience in Radiochemistry, Protein, peptide and small molecule chemistry. In the last ten years I have been involved in different projects for the development of probes for Imaging and Therapy. I had a major role in the successful translation of two PET probes to the clinic that are now in Phase II.
I have contributed and obtained several projects funding, including a EU-Horizon 2020 research and innovation programme (PET3D - PET Imaging in Drug Design and Development) where I had the opportunity to collaborate with researchers within Academia and Industry recognized in the field of PET Imaging. In the last years I have been promotor of several PhD and master students.
Opleiding / Academische kwalificatie
Chemie, Distinction , University of Lisbon
1 nov 2004 → 28 feb 2009
Vingerafdruk
Verdiep u in de onderzoeksgebieden waarop Catarina Xavier actief is. Deze onderwerplabels komen uit het werk van deze persoon. Samen vormen ze een unieke vingerafdruk.
- 1 Soortgelijke profielen
Netwerk
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
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FWOAL951: Ontrafeling van mechanismsen betrokken bij de renale klaring van nanobodies
1/01/20 → 31/12/23
Project: Fundamenteel
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EU514: PET Imaging in Drug Design and Development (PET3D)
Caveliers, V., Xavier, C., Hernot, S. & Devoogdt, N.
1/06/16 → 31/05/20
Project: Fundamenteel
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FWOAL780: Site-specifieke functionalisering van Nanobodies als probes voor Moleculaire beeldvorming and Therapie - Theranostische tool
Muyldermans, S., Xavier, C. & Devoogdt, N.
1/01/15 → 31/12/18
Project: Fundamenteel
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ANI130: Clinical translation of 177Lu-anti-HER2 nanobody for targeted radionuclide therapy of HER2 positieve cancer.
1/01/15 → 31/12/16
Project: Fundamenteel
Onderzoeksoutput
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68Ga-Labeling: Laying the Foundation for an Anti-Radiolytic Formulation for NOTA-sdAb PET Tracers
Baudhuin, H., Cousaert, J., Vanwolleghem, P., Raes, G., Caveliers, V., Keyaerts, M., Lahoutte, T. & Xavier, C., 1 jan 2021, In : Pharmaceuticals. 14, 5, 16 blz., 448.Onderzoeksoutput: Article
Open Access -
Decorating sdAbs with Chelators: Effect of Conjugation on Biodistribution and Functionality
Baudhuin, H., Puttemans, J., Hanssens, H., Vanwolleghem, P., Hernot, S., Raes, G., Xavier, C., Lahoutte, T. & Debie, P., mei 2021, In : Pharmaceuticals. 14, 5, 19 blz., 407.Onderzoeksoutput: Article
Open Access -
Immunogenicity Risk Profile of Nanobodies
Ackaert, C., Smiejkowska, N., Xavier, C., Sterckx, Y. G. J., Denies, S., Stijlemans, B., Elkrim, Y., Devoogdt, N., Caveliers, V., Lahoutte, T., Muyldermans, S., Breckpot, K. & Keyaerts, M., 9 mrt 2021, In : Frontiers in Immunology. 12, 15 blz., 632687.Onderzoeksoutput: Article
Open AccessBestand15 Citaten (Scopus)76 Downloads (Pure) -
Lyophilization of NOTA-sdAbs: First step towards a cold diagnostic kit for 68Ga-labeling
Baudhuin, H., Van Bockstal, P-J., De Beer, T., Vaneycken, I., Bridoux, J., Raes, G., Caveliers, V., Keyaerts, M., Devoogdt, N., Lahoutte, T. & Xavier, C., sep 2021, In : European Journal of Pharmaceutics and Biopharmaceutics. 166, blz. 194-204 11 blz.Onderzoeksoutput: Article
Open AccessBestand14 Downloads (Pure) -
Site-Specific Radiolabeling of a Human PD-L1 Nanobody via Maleimide-Cysteine Chemistry
Chigoho, D. M., Lecocq, Q., Awad, R. M., Breckpot, K., Devoogdt, N., Keyaerts, M., Caveliers, V., Xavier, C. & Bridoux, J., 8 jun 2021, In : Pharmaceuticals. 14, 6, 11 blz., 550.Onderzoeksoutput: Article
Open AccessBestand2 Citaten (Scopus)10 Downloads (Pure)
Prijzen
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Certificat of Young Speaker Award
Quentin Lecocq (Recipient), Katrijn Broos (Recipient), Jessica Bridoux (Recipient), Geert Raes (Recipient), Catarina Xavier (Recipient), Nick Devoogdt (Recipient), Marleen Keyaerts (Recipient) & Karine Breckpot (Recipient), 1 feb 2019
Prijs: Prize (including medals and awards)
Bestand -
ESMI presentation award for best oral presentation
Jessica Bridoux (Recipient), Katrijn Broos (Recipient), Quentin Lecocq (Recipient), Maxine Crauwels (Recipient), Charlotte Martin (Recipient), Frederik Cleeren (Recipient), Mikhail Kondrashov (Recipient), Steven Ballet (Recipient), G. Bormans (Recipient), Magnus Schou (Recipient), Chad Elmore (Recipient), Geert Raes (Recipient), Karine Breckpot (Recipient), Serge Muyldermans (Recipient), Nick Devoogdt (Recipient), Marleen Keyaerts (Recipient), Vicky Caveliers (Recipient) & Catarina Xavier (Recipient), 17 jan 2020
Prijs: Prize (including medals and awards)
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Knowledge for Growth 2018 Ghent - poster award
Katrijn Broos (Recipient), Quentin Lecocq (Recipient), Jessica Bridoux (Recipient), Geert Raes (Recipient), Catarina Xavier (Recipient), Marleen Keyaerts (Recipient), Nick Devoogdt (Recipient) & Karine Breckpot (Recipient), 18 mei 2018
Prijs: Prize (including medals and awards)
Activiteiten
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Noninvasive imaging and inhibition of human programmed death ligand 1 (PD-L1) using nanobody K2 to improve cancer immunotherapy
Robin Maximilian Awad (Contributor), Dora Mugoli Chigoho (Contributor), Katrijn Broos (Contributor), Quentin Lecocq (Contributor), Katty Zeven (Contributor), Thomas Ertveldt (Contributor), Lien De Beck (Contributor), Hannelore Ceuppens (Contributor), Yannick De Vlaeminck (Contributor), Cleo Goyvaerts (Contributor), Steve Schoonooghe (Contributor), Vicky Caveliers (Contributor), Catarina Xavier (Contributor), Jessica Bridoux (Contributor), Geert Raes (Contributor), Marleen Keyaerts (Contributor), Nick Devoogdt (Contributor), Karine Breckpot (Speaker)25 okt 2021 → 26 okt 2021Activiteit: Talk or presentation at a conference
Bestand -
Immuno-PET imaging using the hPD-L1 Nanobody: Radiolabelling strategies
Jessica Bridoux (Speaker), Katrijn Broos (Contributor), Quentin Lecocq (Contributor), Maxine Crauwels (Contributor), Charlotte Martin (Contributor), Frederik Cleeren (Contributor), Mikhail Krivoshapov (Speaker), Steven Ballet (Speaker), G. Bormans (Speaker), Geert Raes (Speaker), Karine Breckpot (Speaker), Serge Muyldermans (Speaker), Magnus Schou (Speaker), Chad Elmore (Speaker), Nick Devoogdt (Speaker), Vicky Caveliers (Speaker), Marleen Keyaerts (Speaker), Catarina Xavier (Speaker)14 jan 2020Activiteit: Talk or presentation at a conference
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2020-74
Tony Lahoutte (Supervisor), Vicky Caveliers (Contributor), Catarina Xavier (Contributor), Jessica Bridoux (Contributor), Herlinde Dierick (Contributor)2020Activiteit: Other
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Design And Preclinical Evaluation Of A Single-label Bimodal Nanobody Tracer For Image-guided Surgery
Pieterjan Debie (Speaker), Bieke De Sloovere (Contributor), Danny M van Willigen (Contributor), Fijs WB van Leeuwen (Contributor), Catarina Xavier (Contributor), Nick Devoogdt (Contributor), Tony Lahoutte (Contributor), Sophie Hernot (Contributor)5 sep 2019Activiteit: Talk or presentation at a conference
Knipsels
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Tackling a shortage of PET scientists and improving healthcare
Jessica Bridoux, Vicky Caveliers & Catarina Xavier
1/10/17
1 Mediabijdrage
Pers / media: !!Research
Scriptie
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CAMEL-KIT: Single-step labeling of single-domain antibody fragments with 68Ga for PET imaging
Auteur: Baudhuin, H. V. & Lahoutte, T., 2021Begeleider: Xavier, C. (Promotor)
Scriptie/masterproef: Doctoral Thesis
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Conversion of Nanobodies to Fluorescent probes with conserved size and functionality
Auteur: Nguyen, T. N. H., Xavier, C., Muyldermans, S. & Pauw, De, P., 5 sep 2014Scriptie/masterproef: Master's Thesis
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Development and preclinical evaluation of novel SPECT and PET tracers for cell death imaging
Auteur: Elvas, F. & Xavier, C., 29 mei 2017Scriptie/masterproef: Doctoral Thesis
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Development of a radioimmunotracer: Gallium-68 labelled hPD-L1 nanobody for PET imaging
Auteur: Bridoux, J., Chigoho, D. M., Xavier, C. & Fransen, P., 31 jan 2020Scriptie/masterproef: Master's Thesis
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Effect of different characteristics of radiometal labelled nanobodies on the kidney retention
Auteur: Crauwels, M., Xavier, C., Muyldermans, S. & Devoogdt, N., 26 okt 2020Scriptie/masterproef: Doctoral Thesis