Projecten per jaar
Persoonlijk profiel
Expertise
I am an experienced scientist and project manager with hands on experience in Radiochemistry, Protein, peptide and small molecule chemistry. In the last ten years I have been involved in different projects for the development of probes for Imaging and Therapy. I had a major role in the successful translation of two PET probes to the clinic that are now in Phase II.
I have contributed and obtained several projects funding, including a EU-Horizon 2020 research and innovation programme (PET3D - PET Imaging in Drug Design and Development) where I had the opportunity to collaborate with researchers within Academia and Industry recognized in the field of PET Imaging. In the last years I have been promotor of several PhD and master students.
Opleiding / Academische kwalificatie
Chemie, Distinction , University of Lisbon
1 nov 2004 → 28 feb 2009
Datum van toekenning: 21 jul 2009
Vingerafdruk
- 1 Soortgelijke profielen
Netwerk
Projecten
- 6 Afgelopen
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EU514: PET Imaging in Drug Design and Development (PET3D)
Caveliers, V., Xavier, C., Hernot, S., Devoogdt, N. & Bridoux, J.
1/06/16 → 31/05/20
Project: Fundamenteel
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ANI130: Clinical translation of 177Lu-anti-HER2 nanobody for targeted radionuclide therapy of HER2 positieve cancer.
1/01/15 → 31/12/16
Project: Fundamenteel
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FWOAL780: Site-specifieke functionalisering van Nanobodies als probes voor Moleculaire beeldvorming and Therapie - Theranostische tool
Muyldermans, S., Xavier, C. & Devoogdt, N.
1/01/15 → 31/12/18
Project: Fundamenteel
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GOA74: Nanobody Translational Molecular Imaging (NTMI)
Lahoutte, T., Caveliers, V., Devoogdt, N., Xavier, C., TCHOUATE GAINKAM Lea, O., D'Huyvetter, M., Hernot, S., Keyaerts, M., Vaneycken, I. & Van Hove, C.
1/01/10 → 31/12/12
Project: Fundamenteel
Onderzoeksoutput
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Assessment of repeatability and uptake quantification of (68)GaNOTA-anti-HER2 sdAb PET/CT in patients with locally advanced or metastatic breast cancer
Gondry, O., Xavier, C., Waelput, W., Al Dabssi, O., Vanhoeij, M., Aspeslagh, S., Joris, S., Fontaine, C., Verfaillie, G., De Greve, J., Glorieus, K., Luyten, I., Vandenbroucke, F., Bourgeois, S., Raes, L., Thyparambil, S., Devoogdt, N., Vaneycken, I., Cousaert, J., Caveliers, V. & 3 anderen, , 15 feb 2022, In: Cancer Research. 82, 4, blz. P3-02-05Onderzoeksoutput: Meeting abstract (Journal)
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68Ga-Labeling: Laying the Foundation for an Anti-Radiolytic Formulation for NOTA-sdAb PET Tracers
Baudhuin, H., Cousaert, J., Vanwolleghem, P., Raes, G., Caveliers, V., Keyaerts, M., Lahoutte, T. & Xavier, C., 1 jan 2021, In: Pharmaceuticals. 14, 5, 16 blz., 448.Onderzoeksoutput: Article › peer review
Open AccessBestand1 Citaat (Scopus)12 Downloads (Pure) -
Decorating sdAbs with Chelators: Effect of Conjugation on Biodistribution and Functionality
Baudhuin, H., Puttemans, J., Hanssens, H., Vanwolleghem, P., Hernot, S., Raes, G., Xavier, C., Lahoutte, T. & Debie, P., mei 2021, In: Pharmaceuticals. 14, 5, 19 blz., 407.Onderzoeksoutput: Article › peer review
Open Access -
Human pd-l1-binding immunoglobulins
Van Ginderachter, J., Raes, G., Devoogdt, N., Keyaerts, M., Lecocq, Q., Xavier, C., Breckpot, K., Broos, K. & Bridoux, J., 2021, Octrooi Nr. EP3758742Onderzoeksoutput: Patent
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Immunogenicity Risk Profile of Nanobodies
Ackaert, C., Smiejkowska, N., Xavier, C., Sterckx, Y. G. J., Denies, S., Stijlemans, B., Elkrim, Y., Devoogdt, N., Caveliers, V., Lahoutte, T., Muyldermans, S., Breckpot, K. & Keyaerts, M., 9 mrt 2021, In: Frontiers in Immunology. 12, 15 blz., 632687.Onderzoeksoutput: Article › peer review
Open AccessBestand50 Citaten (Scopus)143 Downloads (Pure)
Prijzen
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Best Poster Award
Xavier, Catarina (Recipient), 20 apr 2012
Prijs: Prize (including medals and awards)
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Certificat of Young Speaker Award
Lecocq, Quentin (Recipient), Broos, K. (Recipient), Bridoux, Jessica (Recipient), Raes, Geert (Recipient), Xavier, Catarina (Recipient), Devoogdt, Nick (Recipient), Keyaerts, Marleen (Recipient) & Breckpot, Karine (Recipient), 1 feb 2019
Prijs: Prize (including medals and awards)
Bestand -
ESMI presentation award for best oral presentation
Bridoux, Jessica (Recipient), Broos, K. (Recipient), Lecocq, Quentin (Recipient), Crauwels, M. (Recipient), Martin, Charlotte (Recipient), Cleeren, F. (Recipient), Kondrashov, M. (Recipient), Ballet, Steven (Recipient), Bormans, G. (Recipient), Schou, M. (Recipient), Elmore, C. (Recipient), Raes, Geert (Recipient), Breckpot, Karine (Recipient), Muyldermans, Serge (Recipient), Devoogdt, Nick (Recipient), Keyaerts, Marleen (Recipient), Caveliers, Vicky (Recipient) & Xavier, Catarina (Recipient), 17 jan 2020
Prijs: Prize (including medals and awards)
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Knowledge for Growth 2018 Ghent - poster award
Broos, K. (Recipient), Lecocq, Quentin (Recipient), Bridoux, Jessica (Recipient), Raes, Geert (Recipient), Xavier, Catarina (Recipient), Keyaerts, Marleen (Recipient), Devoogdt, Nick (Recipient) & Breckpot, Karine (Recipient), 18 mei 2018
Prijs: Prize (including medals and awards)
Activiteiten
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Using the site-specific radiolabeling of a PD-L1 nanobody via maleimide–cysteine chemistry to develop a PET-tracer as screening tool for personalized oncology treatment
Dora Mugoli Chigoho (Speaker), Jessica Bridoux (Speaker), Catarina Xavier (Speaker), Vicky Caveliers (Speaker), Marleen Keyaerts (Speaker), Nick Devoogdt (Speaker), Karine Breckpot (Speaker), Robin Maximilian Awad (Speaker) & Quentin Lecocq (Speaker)
7 mei 2022Activiteit: Talk or presentation at a conference
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Noninvasive imaging and inhibition of human programmed death ligand 1 (PD-L1) using nanobody K2 to improve cancer immunotherapy
Robin Maximilian Awad (Contributor), Dora Mugoli Chigoho (Contributor), Katrijn Broos (Contributor), Quentin Lecocq (Contributor), Katty Zeven (Contributor), Thomas Ertveldt (Contributor), Lien De Beck (Contributor), Hannelore Ceuppens (Contributor), Yannick De Vlaeminck (Contributor), Cleo Goyvaerts (Contributor), Steve Schoonooghe (Contributor), Vicky Caveliers (Contributor), Catarina Xavier (Contributor), Jessica Bridoux (Contributor), Geert Raes (Contributor), Marleen Keyaerts (Contributor), Nick Devoogdt (Contributor) & Karine Breckpot (Speaker)
25 okt 2021 → 26 okt 2021Activiteit: Talk or presentation at a conference
Bestand -
Immuno-PET imaging using the hPD-L1 Nanobody: Radiolabelling strategies
Jessica Bridoux (Speaker), Katrijn Broos (Contributor), Quentin Lecocq (Contributor), Maxine Crauwels (Contributor), Charlotte Martin (Contributor), Frederik Cleeren (Contributor), Mikhail Krivoshapov (Speaker), Steven Ballet (Speaker), G. Bormans (Speaker), Geert Raes (Speaker), Karine Breckpot (Speaker), Serge Muyldermans (Speaker), Magnus Schou (Speaker), Chad Elmore (Speaker), Nick Devoogdt (Speaker), Vicky Caveliers (Speaker), Marleen Keyaerts (Speaker) & Catarina Xavier (Speaker)
14 jan 2020Activiteit: Talk or presentation at a conference
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2020-74
Tony Lahoutte (Supervisor), Vicky Caveliers (Contributor), Catarina Xavier (Contributor), Jessica Bridoux (Contributor) & Herlinde Dierick (Contributor)
2020Activiteit: Other
Knipsels
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Tackling a shortage of PET scientists and improving healthcare
Jessica Bridoux, Vicky Caveliers & Catarina Xavier
1/10/17
1 Mediabijdrage
Pers / media: !!Research
Scriptie
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Conversion of Nanobodies to Fluorescent probes with conserved size and functionality
Auteur: Nguyen, T. N. H., Xavier, C., Muyldermans, S. & Pauw, De, P., 5 sep 2014Scriptie/Masterproef: Master's Thesis
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Development and preclinical evaluation of novel SPECT and PET tracers for cell death imaging
Auteur: Elvas, F. & Xavier, C., 29 mei 2017Scriptie/Masterproef: Doctoral Thesis
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Development of a radioimmunotracer: Gallium-68 labelled hPD-L1 nanobody for PET imaging
Auteur: Bridoux, J., Chigoho, D. M., Xavier, C. & Fransen, P., 31 jan 2020Scriptie/Masterproef: Master's Thesis
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Effect of different characteristics of radiometal labelled nanobodies on the kidney retention
Auteur: Crauwels, M., Xavier, C., Muyldermans, S. & Devoogdt, N., 26 okt 2020Scriptie/Masterproef: Doctoral Thesis
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New Approaches for development of 68Ga-Labelled Biomolecules for PET-Imaging based on a Siderophore Scaffold
Auteur: Kaeopookum, P., Xavier, C. & Decristoforo, C., sep 2019Scriptie/Masterproef: Doctoral Thesis