Projecten per jaar
Vingerafdruk
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
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FWOAL1071: Lever en hersen organoïden als modellen voor humane pluripotente stamcel-tumorogenese
1/01/23 → 31/12/26
Project: Fundamenteel
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OZRMETH9: De genetische component in infertiliteit en mislukking van vroege menselijke ontwikkeling
1/01/23 → 31/12/29
Project: Fundamenteel
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FWOAL1040: Chromosomale afwijkingen in retinaal pigment epitheel cellen afgeleid van hPSC
1/01/22 → 31/12/25
Project: Fundamenteel
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OZRMETH3: Research at the interface between human genetics and reproduction.
Sermon, K., Seneca, S., Bonduelle, M., De Rycke, M., Devroey, P., Goossens, E., Lissens, W., Spits, C., Stouffs, K., Tournaye, H., Dee, K., Vandermaelen, D., Van Haute, L., Van Saen, D., Van Den Abbeel, E., Liebaers, I., De Meirleir, L., Nekkebroeck, J. & Van De Velde, H.
1/01/09 → 31/12/24
Project: Fundamenteel
Onderzoeksoutput
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Children born after assisted reproduction more commonly carry a mitochondrial genotype associating with low birthweight
Spits, C., Mertens, J., Belva, F., van Montfoort, A. PA., Regin, M., Zambelli, F., Seneca, S., Couvreu De Deckersberg, E., Bonduelle, M-L., Tournaye, H., Stouffs, K., Barbé, K., Smeets, B., Van De Velde, H., Sermon, K. & Blockeel, C., 9 feb 2024, In: Nature Communications. 15, 1, 16 blz., 1232 .Onderzoeksoutput: Article › peer review
Open Access1 Citaat (Scopus) -
Gains of 20q11.21 in human pluripotent stem cells: Insights from cancer research
Krivec, N., Ghosh, M. & Spits, C., 9 jan 2024, In: Stem Cell Reports. 19, blz. 11-27 17 blz.Onderzoeksoutput: Article › peer review
Open Access1 Citaat (Scopus) -
Liver organoids to study if aneuploidy primes human pluripotent stem-cell derived hepatocytes for oncogenic transformation
Huyghebaert, A., Al Delbany, D., Ghosh, M., Kazemzadeh Dastjerd, M., Krivec, N., van Grunsven, L. A. & Spits, C., 8 apr 2024, (Unpublished).Onderzoeksoutput: Poster
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SALL3 mediates the loss of neuroectodermal differentiation potential in human embryonic stem cells with chromosome 18q loss
Spits, C., Lei, Y., Al Delbany, D., Krivec, N., Regin, M., Couvreu De Deckersberg, E., Janssens, C., Ghosh, M. & Sermon, K., 9 apr 2024, In: Stem Cell Reports. 19, 4, blz. 562-578 17 blz.Onderzoeksoutput: Article › peer review
Open Access2 Citaten (Scopus) -
Aneuploid human embryonic stem cells mis-specify during retinal pigment epithelium differentiation but retain their selective advantage
Huyghebaert, A., Lei, Y., Couvreu De Deckersberg, E. & Spits, C., 24 nov 2023, (Unpublished).Onderzoeksoutput: Poster
Datasets
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Modeling of myogenesis using human embryonic stem cells reveals myotonic dystrophy type 1 specific misregulated cellular processes
Spits, C. (Creator), Gene Expression Omnibus (GEO), 2022
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE160916
Dataset
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SALL3 mediates the loss of neuroectodermal differentiation potential in human embryonic stem cells with chromosome 18q loss
Spits, C. (Creator) & Lei, Y. (Creator), Open Science Framework, 2024
DOI: DOI 10.17605/OSF.IO/HPAXC
Dataset
Activiteiten
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Regulators of cell fate decisions in human pre-implantation embryos (Evenement)
Luc Leyns (Jury), Marius Regin (Presenter), Karen Sermon (Supervisor) & Claudia Spits (Supervisor)
28 mrt 2024Activiteit: Member of PhD committee
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KU Leuven (Externe Organisatie)
Johan De Mey (Chair), Eveline Peeters (Member), Gerard Clarke (Member), Joost Smolders (Member), Joao Sabino (Member), Claudia Spits (Member), Marie Beatrice D'Hooghe (Supervisor), Jeroen Raes (Supervisor) & Lindsay Devolder (Supervisor)
21 nov 2022Activiteit: Member of PhD committee
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Aneuploidy induces proteotoxic stress and autophagy-mediated apoptosis in human preimplantation embryos
Marius Regin (Speaker), Edouard Couvreu De Deckersberg (Contributor), Yves Guns (Contributor), Pieter Verdyck (Contributor), Greta Verheyen (Contributor), Hilde Van De Velde (Contributor), Claudia Spits (Contributor) & Karen Sermon (Contributor)
1 jul 2021Activiteit: Talk or presentation at a conference
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Aneuploidy induces proteotoxic stress and autophagy-mediated apoptosis in human preimplantation embryos
Marius Regin (Speaker), Yingnan Lei (Contributor), Edouard Couvreu De Deckersberg (Contributor), Yves Guns (Contributor), Pieter Verdyck (Contributor), Greta Verheyen (Contributor), Hilde Van De Velde (Contributor), Claudia Spits (Contributor) & Karen Sermon (Contributor)
26 nov 2021 → 27 nov 2021Activiteit: Talk or presentation at a conference
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Maternally inherited differences in mitochondrial DNA genotype between ART and spontaneously conceived individuals associate with low birthweight
Joke Mertens (Speaker), Florence Belva (Contributor), Aafke PA van Montfoort (Contributor), Filippo Zambelli (Contributor), Sara Seneca (Contributor), Edouard Couvreu De Deckersberg (Contributor), Mary-Louise Bonduelle (Contributor), Herman Tournaye (Contributor), Katrien Stouffs (Contributor), Kurt Barbé (Contributor), Hubert J M Smeets (Contributor), Hilde Van De Velde (Contributor), Karen Sermon (Contributor), Christophe Blockeel (Contributor) & Claudia Spits (Contributor)
30 jun 2021Activiteit: Talk or presentation at a conference
Knipsels
Scriptie
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(R)evolution in preimplantation genetic diagnosis : development and clinical application of different approaches to preimplantation genetic diagnosis for monogenic disorders.
Auteur: Spits, C., Liebaers, I., Sermon, K., De Rycke, M., Van Schravendijk, C., Van Der Auwera, B., Geraedts, J., Harper, J., Santalo Pedro, J., De Paepe, A., Legius, E. & Timmerman, V., 4 dec 2006Begeleider: Liebaers, I. (Promotor), Sermon, K. (Co-promotor), De Rycke, M. (Co-promotor), Van Schravendijk, C. (Jury), Van Der Auwera, B. (Jury), Geraedts, J. (Externe persoon) (Jury), Harper, J. (Externe persoon) (Jury), Santalo Pedro, J. (Externe persoon) (Jury), De Paepe, A. (Externe persoon) (Jury), Legius, E. (Externe persoon) (Jury) & Timmerman, V. (Externe persoon) (Jury)
Scriptie/Masterproef: Doctoral Thesis