Projecten per jaar
Vingerafdruk
Verdiep u in de onderzoeksgebieden waarop Claudia Spits actief is. Deze onderwerplabels komen uit het werk van deze persoon. Samen vormen ze een unieke vingerafdruk.
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
-
-
BASGO23: OZR Basisfinanciering voor Grote Onderzoeksgroepen - GRAD
1/01/24 → 31/12/29
Project: Fundamenteel
-
OZRMETH9: De genetische component in infertiliteit en mislukking van vroege menselijke ontwikkeling
1/01/23 → 31/12/29
Project: Fundamenteel
-
FWOAL1071: Lever en hersen organoïden als modellen voor humane pluripotente stamcel-tumorogenese
1/01/23 → 31/12/26
Project: Fundamenteel
-
FWOAL1040: Chromosomale afwijkingen in retinaal pigment epitheel cellen afgeleid van hPSC
1/01/22 → 31/12/25
Project: Fundamenteel
-
A call to action for deciphering genetic variants in human pluripotent stem cells for cell therapy
Benvenisty, N., Draper, J. S., Gokhale, P. J., Healy, L. E., Hewitt, Z., Hursh, D., Hodgson, A., Ludwig, T., Mah, N., McClelland, S., Mennecozzi, M., Merkle, F. T., Mountford, J. C., Pera, M. F., Prigione, A., Rodriguez, T., Rossi, A., Rouhani, F., Saeb-Parsy, K., Selfa Aspiroz, L., & 4 anderen, 3 apr. 2025, In: Cell Stem Cell. 32, 4, blz. 508-512 5 blz.Onderzoeksoutput: Article › peer review
Open AccessBestand1 Citaat (Scopus)5 Downloads (Pure) -
A novel liver organoid model using directed mutagenesis to study the oncogenic potential of human pluripotent stem cell-derived hepatocytes
Huyghebaert, A., Al Delbany, D., Krivec, N., van Grunsven, L. A. & Spits, C., 11 apr. 2025, (Unpublished).Onderzoeksoutput: Poster
-
Loss of 18q Alters TGFβ Signalling Affecting Anteroposterior Neuroectodermal Fate in Human Embryonic Stem Cells
lei, Y., Duong, C. M., Krivec, N., Janssens, C., Regin, M., Huyghebaert, A., Deckersberg, E. C. D., Sermon, K., Delbany, D. A. & Spits, C., 5 feb. 2025, In: Cell Proliferation. 12 blz., e13813.Onderzoeksoutput: Article › peer review
Open Access -
The interplay between mitochondrial DNA genotypes, female infertility, ovarian response and mutagenesis in oocytes
Van Der Kelen, A., Li Piani, L., Mertens, J., Regin, M., Couvreu De Deckersberg, E., Van De Velde, H., Sermon, K., Tournaye, H., Verpoest, W., Hes, F. J., Blockeel, C. & Spits, C., 2025, In: Human reproduction open. 2025, 1, 13 blz., hoae074.Onderzoeksoutput: Article › peer review
Open Access1 Citaat (Scopus) -
Aneuploidy as a first genetic hit that enhances the tumorigenic capacity of differentiated human pluripotent stem cells.
Al Delbany, D., Myrthe Mampay , Adhithya Narayanan Srinivasan, Krivec, N., Huyghebaert, A., Lei, Y., Sermon, K., Movahedi, K. & Spits, C., 29 nov. 2024, (Unpublished).Onderzoeksoutput: Poster
Datasets
-
Modeling of myogenesis using human embryonic stem cells reveals myotonic dystrophy type 1 specific misregulated cellular processes
Spits, C. (Creator), Gene Expression Omnibus (GEO), 2022
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE160916
Dataset
-
Gains of 20q11.21 in human pluripotent stem cells: Insights from cancer research
Spits, C. (Creator), OSF, 14 nov. 2024
Dataset
-
-
SALL3 mediates the loss of neuroectodermal differentiation potential in human embryonic stem cells with chromosome 18q loss
Spits, C. (Creator) & Lei, Y. (Creator), Open Science Framework, 2024
Dataset
-
De Novo Cancer Mutations Frequently Associate with Recurrent Chromosomal Abnormalities during Long-Term Human Pluripotent Stem Cell Culture
Al Delbany, D. (Creator), Ghosh, M. (Creator), Krivec, N. (Creator), Huyghebaert, A. (Creator), Regin, M. (Creator), Duong, C. M. (Creator), Lei, Y. (Creator), Sermon, K. (Creator), Olsen, C. (Creator) & Spits, C. (Creator), OSF, 2024
Dataset
Activiteiten
-
Regulators of cell fate decisions in human pre-implantation embryos (Evenement)
Luc Leyns (Jury), Marius Regin (Presenter), Karen Sermon (Supervisor) & Claudia Spits (Supervisor)
28 mrt. 2024Activiteit: Member of PhD committee
-
KU Leuven (Externe Organisatie)
Johan De Mey (Chair), Eveline Peeters (Member), Gerard Clarke (Member), Joost Smolders (Member), Joao Sabino (Member), Claudia Spits (Member), Marie Beatrice D'Hooghe (Supervisor), Jeroen Raes (Supervisor) & Lindsay Devolder (Supervisor)
21 nov. 2022Activiteit: Member of PhD committee
-
Aneuploidy induces proteotoxic stress and autophagy-mediated apoptosis in human preimplantation embryos
Marius Regin (Speaker), Yingnan Lei (Contributor), Edouard Couvreu De Deckersberg (Contributor), Yves Guns (Contributor), Pieter Verdyck (Contributor), Greta Verheyen (Contributor), Hilde Van De Velde (Contributor), Claudia Spits (Contributor) & Karen Sermon (Contributor)
26 nov. 2021 → 27 nov. 2021Activiteit: Talk or presentation at a conference
-
Mitochondrial DNA mosaicism in early human development
Joke Mertens (Speaker), Marius Regin (Contributor), Neelke De Munck (Contributor), Edouard Couvreu De Deckersberg (Contributor), Christophe Blockeel (Contributor), Herman Tournaye (Contributor), Hilde Van De Velde (Contributor), Karen Sermon (Contributor) & Claudia Spits (Contributor)
17 sep. 2021Activiteit: Talk or presentation at a conference
-
Shifting the context of differentiation: chromosomal abnormalities in pluripotent stem cells (Evenement)
Luc Leyns (Jury), Alexander Scott Keller (Presenter), Claudia Spits (Supervisor) & Mieke Geens (Supervisor)
14 jul. 2021Activiteit: Member of PhD committee
Knipsels
Scriptie
-
(R)evolution in preimplantation genetic diagnosis : development and clinical application of different approaches to preimplantation genetic diagnosis for monogenic disorders.
Auteur: Spits, C., Liebaers, I., Sermon, K., De Rycke, M., Van Schravendijk, C., Van Der Auwera, B., Geraedts, J., Harper, J., Santalo Pedro, J., De Paepe, A., Legius, E. & Timmerman, V., 4 dec. 2006Begeleider: Liebaers, I. (Promotor), Sermon, K. (Co-promotor), De Rycke, M. (Co-promotor), Van Schravendijk, C. (Jury), Van Der Auwera, B. (Jury), Geraedts, J. (Externe persoon) (Jury), Harper, J. C. (Externe persoon) (Jury), Santalo Pedro, J. (Externe persoon) (Jury), De Paepe, A. (Externe persoon) (Jury), Legius, E. (Externe persoon) (Jury) & Timmerman, V. (Externe persoon) (Jury)
Scriptie/Masterproef: Doctoral Thesis