Projecten per jaar
Persoonlijk profiel
Expertise
Dimitri De Bundel is a senior lecturer at the Faculty of Medicine and Pharmacy of Vrije Universiteit Brussel. He graduated as a Pharmacist (summa cum laude, 2004) and obtained a PhD in Pharmaceutical Sciences (2009) at Vrije Universiteit Brussel. He pursued postdoctoral training at Karolinska Institutet (Sweden, 2009-2011) and Institut Génomique Fonctionelle (France, 2011-2014). Dimitri De Bundel is a member of the Experimental Pharmacology research group, which employs a range of behavioural, neurochemical and electrophysiological approaches to study the brain. Through precision pharmacology with modulation of cellular activity in brain regions of interest, he aims to contribute to a better understanding and treatment of memory and mood dysfunction in neurological and psychiatric disorders.
Vingerafdruk
Verdiep u in de onderzoeksgebieden waarop Dimitri De Bundel actief is. Deze onderwerplabels komen uit het werk van deze persoon. Samen vormen ze een unieke vingerafdruk.
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
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ANI409: Evaluatie van het therapeutisch potentieel van psilocybine in een preklinisch model van de ziekte van Alzheimer
1/01/25 → 31/12/27
Project: Fundamenteel
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FWOTM1217: Noradrenerge modulatie van contextueel geheugen coderen via hippocampus astrocyt α1A receptoren.
1/10/24 → 30/09/27
Project: Fundamenteel
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HERC66: 3D-CELLMAP: Onthullen van complexe celinteracties in weefsels door middel van 3D super-resolutie proteïne multiplex beeldvorming.
Movahedi, K., Rooman, I., Sermon, K., De Bundel, D., Fioravanti, A., Staels, W., Magez, S., Breckpot, K., De Kock, J., Laoui, D., Goyvaerts, C., Smolders, I., Van Ginderachter, J., Marcelino Rodrigues, R., De Leu, N., van Grunsven, L., Hernot, S., Peeters, E., Vanhaecke, T., De Veirman, K., Ruytinx, J., Van Schependom, J., Kortekaas, I. & Goossens, E.
1/05/24 → 31/05/28
Project: Fundamenteel
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OZR4299: Bilateral cooperation within the framework of a joint doctoral project: benchfee for joint PhD VUB - UHasselt, MEERT Jessy
22/04/24 → 21/04/28
Project: Fundamenteel
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A Bright Future for Photopharmaceuticals Addressing Central Nervous System Disorders. State of the Art and Challenges Toward Clinical Translation
Ganzoni, R. L. Z., Bournons, S. S., Carreira, E. M., De Bundel, D. & Smolders, I., 5 apr. 2025, In: Medicinal Research Reviews. 45, 5, blz. 1323-1374 52 blz.Onderzoeksoutput: Article › peer review
1 Citaat (Scopus) -
Chemogenetic astrocyte modulation reduces spontaneous hippocampal discharges and metabolite changes in an epilepsy mouse model
Nestor, L., Van Den Herrewegen, Y., Dyer, M., Bossuyt, J., Hendrix, E., Buckinx, A., Bournons, S., Viaene, J., Vander Heyden, Y., Van de Casteele, M., Van Eeckhaut, A., Smolders, I. & De Bundel, D., 25 okt. 2025, In: Epilepsia. blz. 1-16 16 blz.Onderzoeksoutput: Article › peer review
Open Access -
Molecular dynamics study of differential effects of serotonin-2A-receptor (5-HT2AR) modulators
Peeters, J., De Bundel, D. & Vanommeslaeghe, K., sep. 2025, In: PLoS Computational Biology. 21, 9, 22 blz., e1013000.Onderzoeksoutput: Article › peer review
Open Access -
Noradrenergic Agonists as Treatment Opportunity of Radiation-Induced Cognitive Decline
De Bie, I., Primac, I., Berden, L., Peeters, B., Neefs, M., Buset, J., De Bundel, D., Boterberg, T., Vanhove, C., Raedt, R. & Benotmane, M. A., 1 dec. 2025, In: International Journal of Radiation Oncology, Biology, Physics. 123, 5, blz. 1353-1367 15 blz.Onderzoeksoutput: Article › peer review
Open Access -
Photopharmacological activation of adenosine A1 receptor signaling suppresses seizures in a mouse model for temporal lobe epilepsy
Spanoghe, J., Wynendaele, E., Vergaelen, M., De Colvenaer, M., Mariman, T., Vonck, K., Carrette, E., Wadman, W., Craey, E., Larsen, L. E., Sprengers, M., Missinne, J., Van Calenbergh, S., De Spiegeleer, B., De Bundel, D., Smolders, I., Boon, P. & Raedt, R., 10 mei 2025, In: Journal of Controlled Release. 381, 1, blz. 1-33 33 blz., 113626.Onderzoeksoutput: Article › peer review
Open Access
Datasets
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Metabolomics data - "Chemogenetic astrocyte modulation reduces spontaneous hippocampal discharges and metabolite changes in an epilepsy mouse model"
Nestor, L. (Creator), Van Den Herrewegen, Y. (Creator), Dyer, M. (Creator), Bossuyt, J. (Creator), Hendrix, E. (Creator), Buckinx, A. (Creator), Bournons, S. (Creator), Viaene, J. (Creator), Vander Heyden, Y. (Creator), Van De Casteele, M. (Creator), Van Eeckhaut, A. (Creator), Smolders, I. (Creator) & De Bundel, D. (Creator), Zenodo, 2025
Dataset
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Molecular dynamics study of differential effects of serotonin-2A-receptor (5-HT2AR) modulators
Peeters, J. (Creator), De Bundel, D. (Creator) & Vanommeslaeghe, K. (Supervisor), Zenodo, jun. 2025
Dataset
Prijzen
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Hugo d'Haenen Award
De Bundel, Dimitri (Recipient), 2 okt. 2015
Prijs: Prize (including medals and awards)
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Les Grandes Avancées en Biologie-Santé du Pôle RABELAIS 2017
De Bundel, Dimitri (Recipient), 4 mei 2017
Prijs: Prize (including medals and awards)
Activiteiten
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Belgian Society for Neuroscience Meeting 2025
Dimitri De Bundel (Member of programme committee)
20 okt. 2025Activiteit: Participation in conference
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Metabolomic profiling of mouse hippocampus to unravel the effects of chemogenetic modulation of astrocytes in a model for temporal lobe epilepsy
Liam Nestor (Speaker), Yvan Vander Heyden (Contributor), Ann Van Eeckhaut (Contributor), Dimitri De Bundel (Contributor) & Ilse Smolders (Contributor)
11 sep. 2024Activiteit: Talk or presentation at a conference
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Pharmacology of psychedelics: to know what we know and to know what we don't.
Dimitri De Bundel (Speaker)
7 okt. 2024Activiteit: Talk or presentation at a conference
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Unraveling the role of peripheral nerve stimulation in tDCS memory enhancement in a novel rat model. Author: van Boekholdt L, Promotor: McLaughlin M. Katholieke Universiteit Leuven. (Evenement)
Dimitri De Bundel (Jury)
19 jan. 2024Activiteit: Member of PhD committee
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Brain Stimulation (Tijdschrift)
Dimitri De Bundel (Peer reviewer)
31 jan. 2024Activiteit: Publication peer-review
Knipsels
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Muizen dienen 'eerste hulp' toe aan bewusteloze soortgenoten, blijkt uit experiment
9/03/25
1 Mediabijdrage
Pers / media: !!Expert Comment
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Ecstasy for Trauma and Magic Mushrooms for Depression?
10/10/24
1 Mediabijdrage
Pers / media: !!Expert Comment
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Trippen tegen trauma's: zijn psychedelica geneeskrachtig?
4/05/22
1 item van Media-aandacht
Pers / media: !!Research
Scriptie
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Anatomical and functional characterization of the neuromedin U system in mouse brain
Auteur: Kereknaoui, I., De Bundel, D. & Smolders, I., 2021Begeleider: Medrano Moya, M. (Co-promotor) & Allaoui, W. (Advisor)
Scriptie/Masterproef: Master's Thesis
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A road toward photoswitchable cannabinoids as a treatment for focal epilepsy
Auteur: De Bundel, D., Smolders, I. & Tan, S., 2021Scriptie/Masterproef: Master's Thesis
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Assessment of HM3DQ- and HM4DI-DREADD functionality in a model for temporal lobe epilepsy.
Auteur: De Bundel, D., Smolders, I. & Bournons, S., 2019Scriptie/Masterproef: Master's Thesis
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Can we measure release of the gliotransmiter glutamate upon chemogenetic modulation of mouse hippocampal astrocytes?
Auteur: De Mooter, M., Smolders, I., Van Eeckhaut, A. & De Bundel, D., 2021Begeleider: Nestor, L. (Advisor)
Scriptie/Masterproef: Master's Thesis
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Centrale ghreline resistentie heeft geen effect op vrees reacties maar onderdrukt de belonende eigenschappen van voedsel
Auteur: De Bundel, D. & Muylle, K., 2017Scriptie/Masterproef: Master's Thesis