Projecten per jaar
Vingerafdruk
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Projecten
- 1 Afgelopen
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FWOSB78: Structurele en functionele karakterisering van het lipide fosfatase Synaptojanin 1 en zijn validatie als nieuwe drug target voor epilepsie
1/11/19 → 31/10/23
Project: Fundamenteel
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Structural and functional insights in Synaptojanin1 and its implication in disease
Martin, E., Paesmans, J., Berghmans, M., Galicia Diaz Santana, C. & Versées, W., 13 mei 2024, (Unpublished).Onderzoeksoutput: Poster
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EndophilinA-dependent coupling between activity-induced calcium influx and synaptic autophagy is disrupted by a Parkinson-risk mutation
Bademosi, A. T., Decet, M., Kuenen, S., Calatayud, C., Swerts, J., Gallego, S. F., Schoovaerts, N., Karamanou, S., Louros, N., Martin, E., Sibarita, J-B., Vints, K., Gounko, N. V., Meunier, F. A., Economou, A., Versées, W., Rousseau, F., Schymkowitz, J., Soukup, S-F. & Verstreken, P., 3 mei 2023, In: Neuron. 111, 9, blz. 1402-1422.e13 21 blz.Onderzoeksoutput: Article › peer review
Open AccessBestand11 Citaten (Scopus)52 Downloads (Pure) -
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New structural and functional insights in Synj1 and its implication in disease.
Martin, E., Paesmans, J., Galicia Diaz Santana, C. & Versées, W., 21 mei 2021.Onderzoeksoutput: Poster
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A structure of substrate-bound Synaptojanin1 provides new insights in its mechanism and the effect of disease mutations
Paesmans, J., Martin, E., Deckers, B., Berghmans, M., Sethi, R., Loeys, Y., Pardon, E., Steyaert, J., Verstreken, P., Galicia, C. & Versées, W., 22 dec 2020, In: eLife. 9, blz. 1-27 27 blz., e64922.Onderzoeksoutput: Article › peer review
Open AccessBestand9 Citaten (Scopus)121 Downloads (Pure)
Datasets
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Crystal structure of the 5-phosphatase domain of Synaptojanin1 in complex with a nanobody
Paesmans, J. (Creator), Versées, W. (Supervisor), Galicia Diaz Santana, C. (Creator) & Martin, E. (Creator), Protein Data Bank in Europe, 30 dec 2020
DOI: 10.2210/pdb7A0V/pdb
Dataset
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Crystal structure of the 5-phosphatase domain of Synaptojanin1 bound to its substrate diC8-PI(3,4,5)P3 in complex with a nanobody.
Paesmans, J. (Creator), Versées, W. (Supervisor), Galicia Diaz Santana, C. (Creator) & Martin, E. (Creator), Protein Data Bank in Europe, 30 dec 2020
DOI: 10.2210/pdb7A17/pdb
Dataset
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Synaptojanin1: van structuuropheldering naar geneesmiddelenontwerp
Ella Martin (Speaker) & Wim Versées (Contributor)
17 mei 2023Activiteit: Talk or presentation at a conference
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Cryo-EM Workshop
Ella Martin (Participant)
12 dec 2019 → 13 dec 2019Activiteit: Participation in workshop, seminar
Scriptie
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Cloning, expression and characterization of the Sac1 domain of the synaptic protein Synaptojanin1
Auteur: Boyana, D. S., Martin, E. & Versées, W., 2021Scriptie/Masterproef: Master's Thesis
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Effect of disease-associated mutations on the function of the human synaptic protein Synaptojanin1
Auteur: Berghmans, M., Martin, E., Versées, W., Remaut, H. & Vanderheyden, P., 2020Scriptie/Masterproef: Master's Thesis