Projecten per jaar
Vingerafdruk
Verdiep u in de onderzoeksgebieden waarop Ella Martin actief is. Deze onderwerplabels komen uit het werk van deze persoon. Samen vormen ze een unieke vingerafdruk.
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
Projecten
- 1 Afgelopen
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FWOSB78: Structurele en functionele karakterisering van het lipide fosfatase Synaptojanin 1 en zijn validatie als nieuwe drug target voor epilepsie
1/11/19 → 31/10/23
Project: Fundamenteel
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Cryo-EM structures of the MnmE-MnmG complex reveal large conformational changes and provide new insights into the mechanism of tRNA modification
Maes, L., Mares-Mejía, I., Martin, E., Bickel, D., Claeys, S., Vranken, W., Fislage, M., Galicia, C. & Versées, W., 9 sep. 2025, In: Nucleic Acids Research. 53, 16, 17 blz., gkaf824.Onderzoeksoutput: Article › peer review
Open Access -
Discovery and Characterization of a Selective Inhibitor of Synaptojanin1 5-Phosphatase Activity
Martin, E., Giakoumakis, D., Paesmans, J., Bisi, N., Drozdzecki, A., Audenaert, D., Haustraete, J., Verstreken, P., Galicia, C., Ballet, S. & Versées, W., 12 sep. 2025, In: ACS Pharmacology and Translational Science. 8, 9, blz. 2996-3006 11 blz.Onderzoeksoutput: Article › peer review
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Synaptojanin1: From Structural Insights to Therapeutic Targeting
Martin, E., Paesmans, J., Berghmans, M., Giakoumakis, D., Galicia Diaz Santana, C. & Versées, W., 2025.Onderzoeksoutput: Poster
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The presynaptic phosphoinositide phosphatase Synaptojanin1: From structural insights to therapeutic targeting
Martin, E., 2025, Crazy Copy Center Productions. 183 blz.Onderzoeksoutput: PhD Thesis
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Cryo-EM structures of the MnmE-MnmG complex reveal large conformational changes and provide new insights into the mechanism of tRNA modification
Maes, L., Martin, E., Bickel, D., Claeys, S., Vranken, W., Fislage, M., Galicia, C. & Versées, W., 30 nov. 2024Onderzoeksoutput: Other contribution
Datasets
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Discovery and characterization of a selective inhibitor of Synaptojanin1 5-phosphatase activity
Martin, E. (Creator), Giakoumakis, D. (Creator), Paesmans, J. (Creator), Bisi, N. (Creator), Drozdzecki, A. (Creator), Audenaert, D. (Creator), Haustraete, J. (Creator), Verstreken, P. (Creator), Galicia Diaz Santana, C. (Creator), Ballet, S. (Creator) & Versées, W. (Creator), Zenodo, 12 sep. 2025
Dataset
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Crystal structure of the 5-phosphatase domain of Synaptojanin1 bound to its substrate diC8-PI(3,4,5)P3 in complex with a nanobody.
Paesmans, J. (Creator), Versées, W. (Supervisor), Galicia Diaz Santana, C. (Creator) & Martin, E. (Creator), Protein Data Bank in Europe, 30 dec. 2020
DOI: 10.2210/pdb7A17/pdb
Dataset
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Crystal structure of the 5-phosphatase domain of Synaptojanin1 in complex with a nanobody
Paesmans, J. (Creator), Versées, W. (Supervisor), Galicia Diaz Santana, C. (Creator) & Martin, E. (Creator), Protein Data Bank in Europe, 30 dec. 2020
DOI: 10.2210/pdb7A0V/pdb
Dataset
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Synaptojanin1: van structuuropheldering naar geneesmiddelenontwerp
Ella Martin (Speaker) & Wim Versées (Contributor)
17 mei 2023Activiteit: Talk or presentation at a conference
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Cryo-EM Workshop
Ella Martin (Participant)
12 dec. 2019 → 13 dec. 2019Activiteit: Participation in workshop, seminar
Scriptie
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Cloning, expression and characterization of the Sac1 domain of the synaptic protein Synaptojanin1
Auteur: Boyana, D. S., Martin, E. & Versées, W., 2021Scriptie/Masterproef: Master's Thesis
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Effect of disease-associated mutations on the function of the human synaptic protein Synaptojanin1
Auteur: Berghmans, M., Martin, E., Versées, W., Remaut, H. & Vanderheyden, P., 2020Scriptie/Masterproef: Master's Thesis