Projecten per jaar
Persoonlijk profiel
Expertise
After I obtained my Master degree at Vrije Universiteit Brussels, faculty Medicine & Pharmacy, I was selected as a PhD candidate at the lab of Molecular Oncology under supervision of Prof. Dr. Ilse Rooman. Here I finished my master thesis, which was focused on pancreatic acinar dedifferentiation. Currently, I perform a PhD study aiming to establish patient-derived organoids as a reliable and efficient model to study fundamental biology of pancreatic cancer. Extensive tissue characterization and sequencing methods clarify whether these models are suitable to ensure patient identity.
My PhD project is sponsored by Innoser NV - a biomedical CRO service - located both in Belgium and The Netherlands. I am working on their PDXO project aiming to develop an innovative platform to test oncological drugs in a preclinical setting.
Opleiding / Academische kwalificatie
Pancreatic cancer, Masters degree, Vrije Universiteit Brussel
Datum van toekenning: 30 jun 2019
Externe posities
Employee, Innoser NV
1 sep 2019 → …
Vingerafdruk
Verdiep u in de onderzoeksgebieden waarop Ellis Michiels actief is. Deze onderwerplabels komen uit het werk van deze persoon. Samen vormen ze een unieke vingerafdruk.
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
Projecten
- 1 Afgelopen
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ANI356: Ruimtelijke kartering van subtypes van pancreaskanker en hun micro-omgevingsniches
1/11/23 → 31/10/24
Project: Fundamenteel
Onderzoeksoutput
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High-resolution and quantitative spatial analysis reveal intra-ductal phenotypic and functional diversification in pancreatic cancer
Michiels, E., Madhloum, H., Van Lint, S., Messaoudi, N., Kunda, R., Martens, S., Giron, P., Olsen, C., Lefesvre, P., Dusetti, N., El Mohajer, L., Tomasini, R., Hawinkels, L. J., Ahsayni, F., Nicolle, R., Arsenijevic, T., Bouchart, C., Van Laethem, J-L. & Rooman, I., jan 2024, In: Journal of pathology. 262, 1, blz. 76-89 14 blz.Onderzoeksoutput: Article › peer review
Open AccessBestand5 Citaten (Scopus)30 Downloads (Pure) -
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Spatial transcriptomic analysis of human Pancreatic Basal Cells reveals PTGES as a potential target for the Basal-Like subtype of Pancreatic Ductal Adenocarcinoma.
Van den Bossche, J-L., Van der Vliet, M., Coolens, K., Michiels, E., Houbracken, I., Baldan, J. & Rooman, I., 18 apr 2024, (Unpublished).Onderzoeksoutput: Poster
Datasets
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Dataset for 'High-resolution and quantitative spatial analysis reveal intra-ductal phenotypic and functional diversification in pancreatic cancer'
Michiels, E. (Creator) & Rooman, I. (Creator), VUB Institutional Data Repository, 19 mrt 2025
Dataset
Prijzen
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Best oral presentation award: In situ detection of KRAS(G12D) mutations in the spatial context of pancreatic cancer subtypes
Michiels, Ellis (Recipient), 11 okt 2022
Prijs: Prize (including medals and awards)
Activiteiten
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A newly identified basal-luminal stratification of human pancreatic ducts is differentially recapitulated in pancreatic cancers
Jan-Lars Van den Bossche (Speaker), Melissa Van der Vliet (Contributor), Ellis Michiels (Contributor), Oier Azurmendi Senar (Contributor), Zeynep Hazal Madran (Contributor), Silke Van Lint (Contributor), Katarina Coolens (Speaker), Montserrat Nacher (Contributor), Tatjana Arsenijevic (Contributor), Pierre Lefesvre (Contributor), Meritxell Rovira (Contributor), Eduard Montanya (Contributor), Jean-Luc Van Laethem (Contributor), Jonathan Baldan (Contributor), Isabelle Houbracken (Contributor) & Ilse Rooman (Contributor)
23 okt 2024Activiteit: Talk or presentation at a conference
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High resolution and quantitative intra-ductal spatial analysis reveals phenotypic and functional diversification in pancreatic cancer
Ellis Michiels (Speaker), Ilse Rooman (Contributor), Nouredin Messaoudi (Contributor), Hediel Madhloum (Contributor), Silke Christophe Van Lint (Contributor), Philippe Giron (Contributor), Catharina Olsen (Contributor), Nelson Dusetti (Contributor) & Jean-Luc Van Laethem (Contributor)
30 apr 2023Activiteit: Talk or presentation at a conference
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Spatial profiling reveals phenotypic diversification at single pancreatic tumor duct level
Ellis Michiels (Speaker) & Ilse Rooman (Speaker)
22 dec 2022Activiteit: Talk or presentation at a conference
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Doctoral Derby: The pre-selection trajectory
Ellis Michiels (Participant)
1 mrt 2022 → 31 mrt 2022Activiteit: Participating in or organizing a public lecture/debate
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Charity Quiz PhD United
Ellis Michiels (Organiser), Margo Willems (Organiser), Niels Vandewalle (Organiser) & Catharina Muylaert (Organiser)
14 dec 2022Activiteit: Participating in or organizing a school event
Knipsels
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Setting up a PDXO platform of pancreatic cancer with spatial-omics characterization
27/09/21
1 Mediabijdrage
Pers / media: !!Public Engagement Activities
Scriptie
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MECOM as a transcriptional regulator of pancreatic acinar dedifferentiation
Auteur: Michiels, E., 30 jun 2019Begeleider: Rooman, I. (Promotor)
Scriptie/Masterproef: Master's Thesis