Projecten per jaar
Persoonlijk profiel
Expertise
After I obtained my Master degree at Vrije Universiteit Brussels, faculty Medicine & Pharmacy, I was selected as a PhD candidate at the lab of Molecular Oncology under supervision of Prof. Dr. Ilse Rooman. Here I finished my master thesis, which was focused on pancreatic acinar dedifferentiation. Currently, I perform a PhD study aiming to establish patient-derived organoids as a reliable and efficient model to study fundamental biology of pancreatic cancer. Extensive tissue characterization and sequencing methods clarify whether these models are suitable to ensure patient identity.
My PhD project is sponsored by Innoser NV - a biomedical CRO service - located both in Belgium and The Netherlands. I am working on their PDXO project aiming to develop an innovative platform to test oncological drugs in a preclinical setting.
Opleiding / Academische kwalificatie
Pancreatic cancer, Masters degree, Dermining the role of a potential regulator of pancreatic acinar dedifferentiation in vivo, Vrije Universiteit Brussel
Datum van toekenning: 30 jun. 2019
Externe posities
Employee, Innoser NV
1 sep. 2019 → …
Vingerafdruk
Verdiep u in de onderzoeksgebieden waarop Ellis Michiels actief is. Deze onderwerplabels komen uit het werk van deze persoon. Samen vormen ze een unieke vingerafdruk.
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
Projecten
- 1 Afgelopen
-
ANI356: Ruimtelijke kartering van subtypes van pancreaskanker en hun micro-omgevingsniches
Rooman, I. (Administrative Promotor) & Michiels, E. (PI (Promotor, Principal Investigator))
1/11/23 → 31/10/24
Project: Fundamenteel
-
Spatial map of native duct cell populations in human pancreas and their representation in pancreatic cancers
Van den Bossche, J.-L., Van der Vliet, M., Michiels, E., Azurmendi Senar, O., Madran, Z., Coolens, K., Van Lint, S., Nacher, M., Arsenijevic, T., Messaoudi, N., Lefesvre, P., Montanya, E., Rovira, M., Van Laethem, J.-L., Baldan, J., Houbracken, I. & Rooman, I., 19 jan. 2025, Biorxiv, 31 blz.Onderzoeksoutput: Voordruk
Open AccessBestand9 Downloads (Pure) -
-
High-resolution and quantitative spatial analysis reveal intra-ductal phenotypic and functional diversification in pancreatic cancer
Michiels, E., Madhloum, H., Van Lint, S., Messaoudi, N., Kunda, R., Martens, S., Giron, P., Olsen, C., Lefesvre, P., Dusetti, N., El Mohajer, L., Tomasini, R., Hawinkels, L. J., Ahsayni, F., Nicolle, R., Arsenijevic, T., Bouchart, C., Van Laethem, J.-L. & Rooman, I., jan. 2024, In: Journal of pathology. 262, 1, blz. 76-89 14 blz.Onderzoeksoutput: Article › peer review
Open AccessBestand5 Citaten (Scopus)56 Downloads (Pure) -
-
Datasets
-
Dataset for 'High-resolution and quantitative spatial analysis reveal intra-ductal phenotypic and functional diversification in pancreatic cancer'
Michiels, E. (Creator) & Rooman, I. (Creator), VUB Institutional Data Repository, 19 mrt. 2025
Dataset
Prijzen
-
Best oral presentation award: In situ detection of KRAS(G12D) mutations in the spatial context of pancreatic cancer subtypes
Michiels, Ellis (Recipient), 11 okt. 2022
Prijs: Prize (including medals and awards)
Activiteiten
-
Spatial map of native duct cell populations in human pancreas and their representation in pancreatic cancers
Van den Bossche, J.-L. (Invited speaker), Van der Vliet, M. (Contributor), Michiels, E. (Contributor), Azurmendi Senar, O. (Contributor), Madran, Z. H. (Contributor), Van Lint, S. (Contributor), Coolens, K. (Contributor), Nacher, M. (Contributor), Arsenijevic, T. (Contributor), Lefesvre, P. (Contributor), Rovira, M. (Contributor), Montanya, E. (Contributor), Laethem, Van, J.-L. (Contributor), Baldan, J. (Contributor), Houbracken, I. (Contributor) & Rooman, I. (Contributor)
14 jun. 2025Activiteit: Talk or presentation at a conference
-
Spatial map of native duct cell populations in human pancreas and their representation in pancreatic cancers
Van den Bossche, J.-L. (Speaker), Van der Vliet, M. (Contributor), Michiels, E. (Contributor), Azurmendi Senar, O. (Contributor), Van Lint, S. (Contributor), Madran, Z. H. (Contributor), Coolens, K. (Contributor), Nacher, M. (Contributor), Arsenijevic, T. (Contributor), Lefesvre, P. (Contributor), Rovira, M. (Contributor), Montanya, E. (Contributor), Van Laethem, J.-L. (Contributor), Baldan, J. (Contributor), Houbracken, I. (Contributor) & Rooman, I. (Contributor)
4 jul. 2025Activiteit: Talk or presentation at a conference
-
A newly identified basal-luminal stratification of human pancreatic ducts is differentially recapitulated in pancreatic cancers
Van den Bossche, J.-L. (Speaker), Van der Vliet, M. (Contributor), Michiels, E. (Contributor), Azurmendi Senar, O. (Contributor), Madran, Z. H. (Contributor), Van Lint, S. (Contributor), Coolens, K. (Speaker), Nacher, M. (Contributor), Arsenijevic, T. (Contributor), Lefesvre, P. (Contributor), Rovira, M. (Contributor), Montanya, E. (Contributor), Van Laethem, J.-L. (Contributor), Baldan, J. (Contributor), Houbracken, I. (Contributor) & Rooman, I. (Contributor)
23 okt. 2024Activiteit: Talk or presentation at a conference
-
High resolution and quantitative intra-ductal spatial analysis reveals phenotypic and functional diversification in pancreatic cancer
Michiels, E. (Speaker), Rooman, I. (Contributor), Messaoudi, N. (Contributor), Madhloum, H. (Contributor), Van Lint, S. C. (Contributor), Giron, P. (Contributor), Olsen, C. (Contributor), Dusetti, N. (Contributor) & Van Laethem, J.-L. (Contributor)
30 apr. 2023Activiteit: Talk or presentation at a conference
-
In situ detection of KRAS(G12D) mutations in the spatial context of pancreatic cancer subtypes
Michiels, E. (Speaker), Rooman, I. (Contributor), Messaoudi, N. (Contributor), Olsen, C. (Contributor), Giron, P. (Contributor), Lefesvre, P. (Contributor) & Frederix, K. (Contributor)
8 okt. 2022 → 11 okt. 2022Activiteit: Talk or presentation at a conference
Knipsels
-
Setting up a PDXO platform of pancreatic cancer with spatial-omics characterization
27/09/21
1 Mediabijdrage
Pers / media: !!Public Engagement Activities
Scriptie
-
MECOM as a transcriptional regulator of pancreatic acinar dedifferentiation
Auteur: Michiels, E., 30 jun. 2019Begeleider: Rooman, I. (Promotor)
Scriptie/Masterproef: Master's Thesis