Onderzoeksoutput per jaar
Onderzoeksoutput per jaar
Onderzoeksoutput
- 20 resultaten
Zoekresultaten
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2021
Epigenetic reprogramming of malignant plasma cells: the therapeutic potential of RASSF proteins and G9a/GLP targeting in Multiple Myeloma.
De Smedt, E., 2021Onderzoeksoutput: PhD Thesis
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G9a/GLP-targeting in MM promotes autophagy-associated apoptosis and boosts proteasome inhibitor mediated cell death
De Smedt, E., Devin, J., Muylaert, C., Robert, N., Requirand, G., Vlummens, P., Vincent, L., Cartron, G., Maes, K., Moreaux, J. & De Bruyne, E., 24 feb 2021, In: Blood Advances. 5, 9, blz. 2325-2338 14 blz.Onderzoeksoutput: Article › peer review
Open AccessBestand14 Citaten (Scopus)20 Downloads (Pure) -
Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma
Herviou, L., Ovejero, S., Izard, F., Karmous-Gadacha, O., Gourzones, C., Bellanger, C., De Smedt, E., Ma, A., Vincent, L., Cartron, G., Jin, J., De Bruyne, E., Grimaud, C., Julien, E. & Moreaux, J., 16 sep 2021, In: Clinical Epigenetics. 13, 1, 18 blz., 174.Onderzoeksoutput: Article › peer review
Open AccessBestand8 Citaten (Scopus)47 Downloads (Pure) -
2019
Myeloid-derived suppressor cells induce multiple myeloma cell survival by activating the AMPK pathway
De Veirman, K., Menu, E., Maes, K., De Beule, N., De Smedt, E., Maes, A., Vlummens, P., Fostier, K., Kassambara, A., Moreaux, J., Van Ginderachter, J. A., De Bruyne, E., Vanderkerken, K. & Van Valckenborgh, E., 1 feb 2019, In: Cancer Letters. 442, blz. 233-241 9 blz.Onderzoeksoutput: Article › peer review
42 Citaten (Scopus) -
Targeting of the histone methyltransferases G9a and GLP in multiple myeloma
De Smedt, E., Devin, J., Liu, H., Vlummens, P., Maes, K., Maes, A., De Veirman, K., Menu, E., Vanderkerken, K., Moreaux, J. & De Bruyne, E., 2019, In: Belgian Journal of Hematology. blz. 52-52 1 blz., PP17.Onderzoeksoutput: Meeting abstract (Journal)
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The anaphase-promoting complex/cyclosome: a new promising target in diffuse large B-cell lymphoma and mantle cell lymphoma
Maes, A., Maes, K., De Raeve, H., De Smedt, E., Vlummens, P., Szablewski, V., Devin, J., Faict, S., De Veirman, K., Menu, E., Offner, F., Spaargaren, M., Moreaux, J., Vanderkerken, K., Van Valckenborgh, E. & De Bruyne, E., 11 jun 2019, In: British Journal of Cancer. 120, 12, blz. 1137-1146 10 blz.Onderzoeksoutput: Article › peer review
Open Access11 Citaten (Scopus) -
2018
Loss of RASSF4 expression in multiple myeloma promotes RAS-driven malignant progression
De Smedt, E., Maes, K., Verhulst, S., Liu, H., Kassambara, A., Maes, A., Robert, N., Heirman, C., Cakana, A., Hose, D., Breckpot, K., van Grunsven, L. A., De Veirman, K., Menu, E., Vanderkerken, K., Moreaux, J. & De Bruyne, E., mrt 2018, In: Cancer Research. 78, 5, blz. 1155-1168 14 blz.Onderzoeksoutput: Article › peer review
Open Access25 Citaten (Scopus) -
The Epigenome in Multiple Myeloma: Impact on Tumor Cell Plasticity and Drug Response
De Smedt, E., Lui, H., Maes, K., De Veirman, K., Menu, E., Vanderkerken, K. & De Bruyne, E., 11 dec 2018, In: Frontiers in Oncology. 8, DEC, 18 blz., 566.Onderzoeksoutput: Scientific review › peer review
Open Access34 Citaten (Scopus) -
2017
Histone Methyltransferases G9a and GLP; Identification and Validation of Novel Therapeutic Targets for Multiple Myeloma Treatment
De Smedt, E., Devin, J., Liu, H., Maes, A., Maes, K., De Veirman, K., Menu, E., Vanderkerken, K., Moreaux, J. & De Bruyne, E., 2017, In: Blood. 130, blz. 4356-4356Onderzoeksoutput: Meeting abstract (Journal)
Open Access -
The Anaphase Promoting Complex/Cyclosome: A New Promising Target in Mantle Cell Lymphoma and Diffuse Large B Cell Lymphoma
Maes, A., De Smedt, E., De Veirman, K., Maes, K., Menu, E., Van Valckenborgh, E., Vanderkerken, K. & De Bruyne, E., 2017, In: Blood. 130, blz. 2757-2757 1 blz.Onderzoeksoutput: Meeting abstract (Journal)
Open Access -
The anaphase-promoting-complex/cyclosome: a new promising target in mantle cell lymphoma and diffuse large B cell lymphoma
Maes, A., De Smedt, E., De Veirman, K., Maes, K., Menu, E., Van Valckenborgh, E., Vanderkerken, K. & De Bruyne, E., 2017, In: Belgian Journal of Hematology. blz. 16-16 1 blz.Onderzoeksoutput: Meeting abstract (Journal)
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The histone methyltransferases G9a/GLP: new promising targets for the treatment of multiple myeloma
De Smedt, E., Devin, J., Liu, H., Maes, A., Maes, K., De Veirman, K., Menu, E., Moreaux, J. & De Bruyne, E., 2017, In: Belgian Journal of Hematology. blz. 16-16 1 blz.Onderzoeksoutput: Meeting abstract (Journal)
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2016
RAS Association Domain Family Member 4 (RASSF4): A New Potent Tumor Suppressor in Multiple Myeloma
De Smedt, E., Maes, K., Verhulst, S., Lui, H., Kassambara, A., Maes, A., Hose, D., Breckpot, K., Moreaux, J. & De Bruyne, E., 2016, In: Blood. 128, 22, 1 blz., 2057.Onderzoeksoutput: Meeting abstract (Journal)
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SET8 Is a Potential Therapeutic Target in MM
Herviou, L., Izard, F., De Bruyne, E., De Smedt, E., Ma, A., Jin, J., Vanderkerken, K., Julien, E. & Moreaux, J., 2016, In: Blood. 128, 22, 1 blz., 4435.Onderzoeksoutput: Meeting abstract (Journal)
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2015
In vivo treatment with epigenetic modulating agents induces transcriptional alterations associated with prognosis and immunomodulation in multiple myeloma
Maes, K., De Smedt, E., Kassambara, A., Hose, D., Seckinger, A., Van Valckenborgh, E., Menu, E., Klein, B., Vanderkerken, K. & De Bruyne, E., 31 jan 2015, In: Belgian Journal of Hematology.Onderzoeksoutput: Meeting abstract (Journal)
21 Citaten (Scopus) -
RASSF4 functions as a tumor suppressor in Multiple Myeloma
De Smedt, E., Maes, K., Verhulst, S., Heirman, C., Hose, D., Van Valckenborgh, E., Menu, E., Breckpot, K., van Grunsven, L. A., Moreaux, J. & De Bruyne, E., 23 sep 2015, In: Clinical Lymphoma & Myeloma. 15, blz. 227-227 1 blz.Onderzoeksoutput: Meeting abstract (Journal)
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2014
In vivo gene expression profling in the murine 5T33MM model identifies epigenetic-regulated genes predictive for prognosis and drug sensitivity
Maes, K., De Smedt, E., Van Valckenborgh, E., Menu, E., Vanderkerken, K. & De Bruyne, E., 30 jan 2014, In: Belgian Journal of Hematology.Onderzoeksoutput: Meeting abstract (Journal)
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In vivo treatment withepigenetic modulating agents induces transcriptional alterations associated with prognosis and immunomodulation in multiple myeloma
Maes, K., De Smedt, E., Kassambara, A., Hose, D., Seckinger, A., Van Valckenborgh, E., Menu, E., Klein, B., Vanderkerken, K., Moreaux, J. & De Bruyne, E., 26 dec 2014, In: Oncotarget. 6, 5, blz. 3319-3334 15 blz.Onderzoeksoutput: Article › peer review
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The in vivo Transcriptional Response Towards Epigenetic Modulating Agents in Multiple Myeloma
Maes, K., De Smedt, E., Kassambara, A., Hose, D., Seckinger, A., Van Valckenborgh, E., Menu, E., Klein, B., Vanderkerken, K., Moreaux, J. & De Bruyne, E., 6 dec 2014, In: Blood. 124, 21, blz. 3375 1 blz.Onderzoeksoutput: Conference paper
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The role of DNA damage and repair in decitabine-mediated apoptosis in multiple myeloma.
Maes, K., De Smedt, E., Lemaire, M., De Raeve, H., Menu, E., Van Valckenborgh, E., Mcclue, S., Vanderkerken, K. & De Bruyne, E., 22 mrt 2014, In: Oncotarget. 5, 10, blz. 3115-3129 15 blz.Onderzoeksoutput: Article › peer review
47 Citaten (Scopus)