Projecten per jaar
Persoonlijk profiel
Expertise
I am a PhD student currently employed at the Laboratory for Molecular and Cellular Therapy (LMCT, VUB). I have obtained a Master degree in Biomedical Sciences at the Vrije Universiteit Brussel. My PhD project is a joint project between the LMCT and ICMI research groups in which I will focus on the development of an in vivo nanoCAR-T cell therapy.
Vingerafdruk
Verdiep u in de onderzoeksgebieden waarop Fien Meeus actief is. Deze onderwerplabels komen uit het werk van deze persoon. Samen vormen ze een unieke vingerafdruk.
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
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ANI395: CARGO: advancing chimeric antigen receptor T cell therapy using nanobodydisplaying lentiviral vectors
1/11/24 → 31/10/25
Project: Fundamenteel
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IOFPOC42: IOF proof of Concept: Modificatie van T-cellen in situ om de functionaliteit te wijzigen.
Devoogdt, N., Breckpot, K., Meeus, F., De Groof, T. & De Vlaeminck, Y.
1/01/21 → 31/12/22
Project: Toegepast
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FWOSB101: CARGO: bevorderen van chimere antigen receptor T-celtherapie m.b.v. nanobody bevattende lentivirale vectoren.
1/11/20 → 31/10/24
Project: Fundamenteel
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Anti-Idiotypic VHHs and VHH-CAR-T Cells to Tackle Multiple Myeloma: Different Applications Call for Different Antigen-Binding Moieties
Hanssens, H., Meeus, F., Gesquiere, E. L., Puttemans, J., Vlaeminck, Y. D., Veirman, K. D., Breckpot, K. & Devoogdt, N., 22 mei 2024, In: International Journal of Molecular Sciences. 25, 11, 16 blz., 5634.Onderzoeksoutput: Article › peer review
Open AccessBestand2 Downloads (Pure) -
Scrutiny of chimeric antigen receptor activation by the extracellular domain: experience with single domain antibodies targeting multiple myeloma cells highlights the need for case-by-case optimization
Hanssens, H., Meeus, F., De Vlaeminck, Y., Lecocq, Q., Puttemans, J., Debie, P., De Groof, T. W. M., Goyvaerts, C., De Veirman, K., Breckpot, K. & Devoogdt, N., 2024, In: Frontiers in Immunology. 15, 15 blz., 1389018.Onderzoeksoutput: Article › peer review
Open Access -
Development and evaluation of nanobody tracers for noninvasive nuclear imaging of the immune-checkpoint TIGIT
Zeven, K., De Groof, T. W. M., Ceuppens, H., Awad, R. M., Ertveldt, T., de Mey, W., Meeus, F., Raes, G., Breckpot, K. & Devoogdt, N., 20 sep 2023, In: Frontiers in Immunology. 14, 1, 16 blz., 1268900.Onderzoeksoutput: Article › peer review
Open AccessBestand6 Citaten (Scopus)26 Downloads (Pure) -
In vitro modelling of local gene therapy with IL-15/IL-15Rα and a PD-L1 antagonist in melanoma reveals an interplay between NK cells and CD4+ T cells
Awad, R. M., De Vlaeminck, Y., Meeus, F., Ertveldt, T., Zeven, K., Ceuppens, H., Goyvaerts, C., Verdonck, M., Salguero, G., Raes, G., Devoogdt, N. & Breckpot, K., dec 2023, In: Scientific reports. 13, 1, blz. 1-13 13 blz., 18995.Onderzoeksoutput: Article › peer review
Open AccessBestand2 Citaten (Scopus)8 Downloads (Pure) -
Emerging applications of nanobodies in cancer therapy
Awad, R. M., Meeus, F., Ceuppens, H., Ertveldt, T., Hanssens, H., Lecocq, Q., Mateusiak, L., Zeven, K., Valenta, H., De Groof, T. W. M., De Vlaeminck, Y., Krasniqi, A., De Veirman, K., Goyvaerts, C., D'Huyvetter, M., Hernot, S., Devoogdt, N. & Breckpot, K., 2022, In: International review of cell and molecular biology. 369, blz. 143-199 57 blz.Onderzoeksoutput: Scientific review › peer review
Open AccessBestand14 Citaten (Scopus)456 Downloads (Pure)
Activiteiten
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Development of an in vitro hot tumor model for immunotherapeutic drug screening
Robin Maximilian Awad (Presenter), Fien Meeus (Contributor), Yannick De Vlaeminck (Contributor), Nick Devoogdt (Contributor) & Karine Breckpot (Contributor)
21 sep 2022Activiteit: Talk or presentation at a conference
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Human relevant models for drug research and development
Fien Meeus (Speaker), Robin Maximilian Awad (Contributor), Nick Devoogdt (Contributor), Sandra Tuyaerts (Contributor), Cleo Goyvaerts (Contributor), Yannick De Vlaeminck (Contributor), Bart Neyns (Contributor) & Karine Breckpot (Contributor)
8 okt 2021Activiteit: Talk or presentation at a workshop/seminar
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2021-80
Nick Devoogdt (Supervisor), Timo De Groof (Contributor), Fien Meeus (Contributor), Karine Breckpot (Contributor) & Yannick De Vlaeminck (Contributor)
2021 → …Activiteit: Other
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FWO-SB fellowship: CARGO: advancing chimeric antigen receptor T cell therapy using nanobody-displaying lentiviral vectors.
Fien Meeus (Participant) & Fien Meeus (Contributor)
1 nov 2020 → 31 okt 2024Activiteit: Written proposal
Knipsels
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Betaalbare kankerimmunotherapie
Karine Breckpot, Nick Devoogdt, Yannick De Vlaeminck & Fien Meeus
8/02/22
1 item van Media-aandacht
Pers / media: !!Research
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VUB-onderzoek naar gedeeltelijk falen immuuntherapie
Karine Breckpot, Fien Meeus & Yannick De Vlaeminck
3/02/22
1 Mediabijdrage
Pers / media: !!Research
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VUB-onderzoekers en start-up Esobiotec streven naar betaalbare kankerimmunotherapie
Karine Breckpot, Nick Devoogdt, Yannick De Vlaeminck & Fien Meeus
31/01/22
1 Mediabijdrage
Pers / media: !!Research
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VUB-onderzoekers en start-up Esobiotec willen kankerimmunotherapie betaalbaarder maken
Karine Breckpot, Nick Devoogdt, Fien Meeus & Yannick De Vlaeminck
31/01/22
1 item van Media-aandacht
Pers / media: !!Research
Scriptie
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Assessment of antigen-binding domain parameters important for adequate CAR-T-cell activation: evaluating different SLAMF7-targeting nanobodies.
Auteur: Meeus, F., Hanssens, H., De Veirman, K. & Devoogdt, N., 19 jun 2020Begeleider: Hanssens, H. (Advisor)
Scriptie/Masterproef: Master's Thesis