Persoonlijk profiel
Expertise
- Dr. Gutierrez research focuses on the study of cell signaling with an emphasis in proteins post-translational modifications such as phosphorylation and ubiquitination
Expertise
Dr. Gutierrez is an expert in the cell division cycle
Expertise
Dr. Gutierrez is an expert in Cancer Biology
Opleiding / Academische kwalificatie
Molecular and Cellular Biology, post-doc, Cell Signaling in Normal, Stem, and Cancer Human Cells, Sanford Burnham Prebys Medical Discovery Institute
Datum van toekenning: 28 feb. 2012
Molecular and Cell Biology, PhD, Roles and Regulations of RINGO/Speedy during Xenopus laevis oocytes meiotic maturation, European Molecular Bioogy Laboratory (EMBL)
1 sep. 2000 → 31 aug. 2004
Datum van toekenning: 1 jul. 2004
Vingerafdruk
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Projecten
- 4 Afgelopen
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FWOTM858: Co-inhibitie van Serine-Threonine-Tyrosine Kinase 1 en Epidermale Groeifactor Receptor als een verbeterde doelgerichte therapie in niet-kleincellige longkanker.
De Grève, J. (Administrative Promotor), Teugels, E. (CoI (Co-Promotor)), Gutierrez Gonzalez, G. (CoI (Co-Promotor)) & Eggermont, C. (!!On behalf of)
1/10/17 → 30/09/21
Project: Fundamenteel
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IRP9_a: Interdisciplinair Netwerk voor Fundamenteel en Medische Onderzoek naar Longkanker
De Grève, J. (Administrative Promotor), Ballet, S. (Co-Promoter) & Gutierrez Gonzalez, G. (Co-Promoter)
1/07/16 → 30/06/21
Project: Fundamenteel
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FWOAL711: Het deubiquitinating enzyme USP13 als een specifiek therapeutisch mikpunt in glioblastoma
Gutierrez Gonzalez, G. (Administrative Promotor)
1/01/14 → 31/12/16
Project: Fundamenteel
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OZR2339: Functie en rol van het APC/C in neurale stamceldifferentiatie
Gutierrez Gonzalez, G. (Administrative Promotor) & Snyder, E. (Medewerker)
1/03/12 → 1/03/16
Project: Fundamenteel
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Protein kinase Sut1 from the Crenarchaeon Sulfolobus acidocaldarius displays tyrosine phsophorylation activity
Maklad, H. R. M. A., Pyr dit Ruys, S., Bervoets, I., Vertommen, D., Gutierrez, G. J., Vranken, W., Siebers, B. & Peeters, E., 14 jan. 2024, Biorxiv, 23 blz.Onderzoeksoutput: Voordruk
Open Access -
Inhibition of PLK1 Destabilizes EGFR and Sensitizes EGFR-Mutated Lung Cancer Cells to Small Molecule Inhibitor Osimertinib
Eggermont, C., Gutierrez, G. J., De Grève, J. & Giron, P., mei 2023, In: Cancers. 15, 9, 2589.Onderzoeksoutput: Article › peer review
Open AccessBestand6 Citaten (Scopus)91 Downloads (Pure) -
The EGFR-STYK1-FGF1 axis sustains functional drug tolerance to EGFR inhibitors in EGFR-mutant non-small cell lung cancer
Eggermont, C., Giron, P., Noeparast, M., Vandenplas, H., Aza-Blanc, P., Gutierrez, G. J. & De Grève, J., 15 jul. 2022, In: Cell & Death Disease. 13, 7, 11 blz., 611.Onderzoeksoutput: Article › peer review
Open AccessBestand9 Citaten (Scopus)153 Downloads (Pure) -
Structure-Activity Relationship (SAR) Study of Spautin-1 to Entail the Discovery of Novel NEK4 Inhibitors
Elsocht, M., Giron, P., Maes, L., Versées, W., Gutierrez, G. J., De Grève, J. & Ballet, S., 2 jan. 2021, In: International Journal of Molecular Sciences. 22, 2, blz. 1-40 40 blz., 635.Onderzoeksoutput: Article › peer review
Open AccessBestand7 Citaten (Scopus)327 Downloads (Pure) -
Targeting USP13 mediated drug tolerance increases the efficacy of EGFR inhibition of mutant EGFR in Non-Small Cell Lung Cancer
Giron, P., Eggermont, C., Noeparast, A., Vandenplas, H., Teugels, E., Forsyth, R., De Wever, O., Aza-Blanc, P., Gutierrez, G. J. & De Grève, J., 15 mei 2021, In: International Journal of Cancer. 148, 10, blz. 2579-2593 15 blz.Onderzoeksoutput: Article › peer review
Open Access20 Citaten (Scopus)
Activiteiten
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PhD defense Hassan Maklad - Phosphorylation of transcription factors as a signal transduction mechanism in the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius (Evenement)
Loris, R. (Jury), Maklad, H. R. M. A. (Presenter), Peeters, E. (Supervisor), Maes, D. (Chair), Gutierrez Gonzalez, G. (Jury), Roovers, M. (Jury) & Quax, T. (Jury)
5 sep. 2020Activiteit: Member of PhD committee
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Subhash Medhi
Gutierrez Gonzalez, G. (Supervisor)
1 mrt. 2014 → 1 sep. 2014Activiteit: Hosting an academic visitor
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Genes & Cancer (Tijdschrift)
Gutierrez Gonzalez, G. (Peer reviewer)
1 jan. 2012 → …Activiteit: Publication peer-review
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Wiley Encyclopedia of Chemical Biology (Tijdschrift)
Gutierrez Gonzalez, G. (Peer reviewer)
1 jan. 2012 → …Activiteit: Publication peer-review
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The FASEB Journal (Tijdschrift)
Gutierrez Gonzalez, G. (Peer reviewer)
1 jan. 2012 → …Activiteit: Publication peer-review
Scriptie
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Characterization of a novel transcription factor implicated in heat shock response in Sulfolobus acidocaldarius
De Koning, E. ((PhD) Student), Peeters, E. (Promotor), Hernalsteens, J.-P. (Jury) & Gutierrez Gonzalez, G. (Jury), Lemmens, L. (Advisor), 24 jun. 2016Scriptie/Masterproef: Master's Thesis
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Nanog in stem cells
Gutierrez Gonzalez, G. (Promotor) & Gryp, J. ((PhD) Student), 1 sep. 2013Scriptie/Masterproef: Master's Thesis