Projecten per jaar
Persoonlijk profiel
Expertise
PhD student with a focus on cell-based cancer (immuno)therapy and targeted cancer imagig. Experienced in nanobody generation, protein expression and purification, (in vivo) molecular nuclear imaging, flow cytometry, radioactive labelings, surface plasmon resonance, cell culture, subcloning and cell-based assays.
Vingerafdruk
Verdiep u in de onderzoeksgebieden waarop Heleen Hanssens actief is. Deze onderwerplabels komen uit het werk van deze persoon. Samen vormen ze een unieke vingerafdruk.
- 1 Soortgelijke profielen
Netwerk
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
Projecten
- 1 Actief
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FWOSB58: Ontwikkeling van een NanoCAR-T cel benadering voor de behandeling van multipel myeloom
Hanssens, H., Devoogdt, N., De Veirman, K. & Breckpot, K.
1/01/19 → 31/12/22
Project: Fundamenteel
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The road to personalized myeloma medicine: Patient-specific single-domain antibodies for anti-idiotypic radionuclide therapy
Puttemans, J., Stijlemans, B., Keyaerts, M., Vander Meeren, S., Renmans, W., Fostier, K., Debie, P., Hanssens, H., Rodak, M., Pruszynski, M., De Veirman, K., Vanderkerken, K., Lahoutte, T., Morgenstern, A., Bruchertseifer, F., Devoogdt, N. & D'Huyvetter, M., jan 2022, In : Molecular Cancer Therapeutics. 21, 1, blz. 159-169 10 blz.Onderzoeksoutput: Article
Open AccessBestand14 Downloads (Pure) -
CS1-specific single-domain antibodies labeled with Actinium-225 prolong survival and increase CD8+ T cells and PD-L1 expression in Multiple Myeloma
De Veirman, K., Puttemans, J., Krasniqi, A., Ertveldt, T., Hanssens, H., Romao, E., Hose, D., Goyvaert, C., Vlummens, P., Muyldermans, S., Breckpot, K., Bruchertseifer, F., Morgenstern, A., D'Huyvetter, M. & Devoogdt, N., 2021, In : Oncoimmunology. 10, 1, 11 blz., 2000699.Onderzoeksoutput: Article
Open Access -
Decorating sdAbs with Chelators: Effect of Conjugation on Biodistribution and Functionality
Baudhuin, H., Puttemans, J., Hanssens, H., Vanwolleghem, P., Hernot, S., Raes, G., Xavier, C., Lahoutte, T. & Debie, P., mei 2021, In : Pharmaceuticals. 14, 5, 19 blz., 407.Onderzoeksoutput: Article
Open Access -
The antigen-binding moiety in the driver's seat of CARs
Hanssens, H., Meeus, F., De Veirman, K., Breckpot, K. & Devoogdt, N., 24 mei 2021, In : Medicinal Research Reviews. 42, 1, blz. 306-342 37 blz.Onderzoeksoutput: Article
Open Access -
The therapeutic potential of Actinium-225-labeled CS1-specific single-domain antibodies for the treatment of Multiple Myeloma
De Veirman, K., Puttemans, J., Krasniqi, A., Hanssens, H., Romao, E., Vlummens, P., Breckpot, K., Hose, D., Bruchertseifer, F., Morgenstern, A., D'Huyvetter, M. & Devoogdt, N., 8 sep 2021, blz. 79-79. 1 blz.Onderzoeksoutput: Unpublished abstract
Activiteiten
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EHA-EBMT 3rd European CAR T-Cell Meeting
Heleen Hanssens (Participant)4 feb 2021 → 6 feb 2021Activiteit: Participation in conference
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VUB Phd Day 2021
Heleen Hanssens (Chair)27 mei 2021Activiteit: Participating in or organizing a public lecture/debate
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Workshop Immuno-Imaging and Molecular Therapy - Hands-on session: Nanobody lead selection analysis
Heleen Hanssens (Speaker), Janik Puttemans (Speaker)5 apr 2019Activiteit: Talk or presentation at a workshop/seminar
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BCLAS Symposium
Heleen Hanssens (Participant)20 mei 2019 → 21 mei 2019Activiteit: Participation in conference
Scriptie
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Assessment of antigen-binding domain parameters important for adequate CAR-T-cell activation: evaluating different SLAMF7-targeting nanobodies.
Auteur: Meeus, F., Hanssens, H., De Veirman, K. & Devoogdt, N., 19 jun 2020Begeleider: Hanssens, H. (Advisor)
Scriptie/masterproef: Master's Thesis
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'Development of a NanoCAR approach for the treatment of multiple myeloma
Auteur: Devoogdt, N., Breckpot, K., De Veirman, K. & Hanssens, H., 2022Scriptie/masterproef: Doctoral Thesis
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Generation and validation of nanobodies targeting brain tumors with aberrant expression of epidermal growth factor receptor and human epidermal growth factor receptor 2
Auteur: Hanssens, H., Devoogdt, N., Muyldermans, S. & Puttemans, J., 13 sep 2018Begeleider: Puttemans, J. (Advisor)
Scriptie/masterproef: Master's Thesis