Onderzoeksoutput per jaar
Onderzoeksoutput per jaar
Onderzoeksoutput
- 22 resultaten
Zoekresultaten
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2024
A robust high-throughput screening system to assess bacterial tyrosine ammonia lyase activity in the context of tyrosine inherited metabolic disorders
Nulmans, I., Laga, C. A., Salvi, N. S., Desmet, L., Lequeue, S., Neuckermans, J., Schwaneberg, U. & De Kock, J., 27 sep 2024, In: Scientific reports. 14, 1, 1 blz., 22175.Onderzoeksoutput: Article › peer review
Open Access -
2023
An AAV-mediated liver-directed gene therapy metabolically corrects alkaptonuria in an Hgd deficient mouse model
Lequeue, S., Norman, B. P., Neuckermans, J., Colemonts-Vroninks, H., Hughes, J. H., Claes, P., Heymans, A., Ranganath, L., Gallagher, J., Vanhaecke, T., Bou-Gharios, G. & De Kock, J., 14 aug 2023.Onderzoeksoutput: Poster
Open Access -
Development of a robust high-throughput screenings system for the evaluation of tyrosine ammonia lyases in the context of inborn errors of tyrosine metabolism
Nulmans, I., Laga, C. A., Salvi, N. S., Desmet, L., Lequeue, S., Neuckermans, J. & De Kock, J., 19 sep 2023.Onderzoeksoutput: Poster
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Engineering of triketone-insensitive human 4-hydroxyphenylpyruvate dioxygenase enzymes as basis to develop e new gene therapy for hereditary tyrosinemia type 1
Neuckermans, J., 2023, 258 blz.Onderzoeksoutput: PhD Thesis
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Hereditary Tyrosinemia Type 1 Mice under Continuous Nitisinone Treatment Display Remnants of an Uncorrected Liver Disease Phenotype
Neuckermans, J., Lequeue, S., Claes, P., Heymans, A., Hughes, J. H., Colemonts-Vroninks, H., Marcélis, L., Casimir, G., Goyens, P., Martens, G. A., Gallagher, J. A., Vanhaecke, T., Bou-Gharios, G. & De Kock, J., 11 mrt 2023, In: Genes. 14, 3, 15 blz., 693.Onderzoeksoutput: Article › peer review
Open AccessBestand1 Citaat (Scopus)37 Downloads (Pure) -
2022
A robust bacterial high-throughput screening system to evaluate single nucleotide polymorphisms of human homogentisate 1,2-dioxygenase in the context of alkaptonuria
Lequeue, S., Neuckermans, J., Nulmans, I., Schwaneberg, U., Vanhaecke, T. & De Kock, J., 14 nov 2022, In: Scientific Reports. 12, 1, blz. 1-15 15 blz., 19452.Onderzoeksoutput: Article › peer review
Open AccessBestand2 Citaten (Scopus)37 Downloads (Pure) -
Development of a robust high-throughput screening system for the evaluation of human homogentisate 1,2-dioxygenase missense variants in the context of rare disease alkaptonuria
Lequeue, S., Neuckermans, J., Vanhaecke, T. & De Kock, J., 2022.Onderzoeksoutput: Poster
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Development of a robust high-throughput screening system to evaluate single nucleotide polymorphisms of human homogentisate 1,2-dioxygenase in the context of rare disease alkaptonuria
Lequeue, S., Neuckermans, J., Vanhaecke, T. & De Kock, J., 14 nov 2022.Onderzoeksoutput: Poster
Open Access -
2021
High-throughput quantification of ochronotic pigment formation in Escherichia coli to evaluate the potency of human 4-hydroxyphenylpyruvate dioxygenase inhibitors in multi-well format
Neuckermans, J., Lequeue, S., Mertens, A., Branson, S., Schwaneberg, U. & De Kock, J., jan 2021, In: MethodsX. 8, 11 blz., 101181.Onderzoeksoutput: Article › peer review
Open AccessBestand1 Citaat (Scopus)107 Downloads (Pure) -
Oxidative Stress, Glutathione Metabolism, and Liver Regeneration Pathways Are Activated in Hereditary Tyrosinemia Type 1 Mice upon Short-Term Nitisinone Discontinuation
Colemonts-Vroninks, H., Neuckermans, J., Marcelis, L., Claes, P., Branson, S., Casimir, G., Goyens, P., Martens, G. A., Vanhaecke, T. & De Kock, J., jan 2021, In: Genes. 12, 1, blz. 1-16 16 blz., 3.Onderzoeksoutput: Article › peer review
Open AccessBestand8 Citaten (Scopus)155 Downloads (Pure) -
2020
Directed protein evolution as a tool to innovate gene therapy for hereditary tyrosinemia type 1
Neuckermans, J., Colemonts-Vroninks, H., Marcélis, L., Mertens, A., Schwaneberg, U. & De Kock, J., mrt 2020.Onderzoeksoutput: Poster
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Directed protein evolution as a tool to innovate gene therapy for hereditary tyrosinemia type 1
Neuckermans, J., Colemonts-Vroninks, H., Marcélis, L., Mertens, A., Schwaneberg, U. & De Kock, J., 2020, In: Journal of Hepatology. 73, 1, blz. S543-S543Onderzoeksoutput: Meeting abstract (Journal)
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Impact of nitisinone treatment and discontinuation on the metabolome of wildtype and hereditary tyrosinemia type 1 mice
Colemonts-Vroninks, H., Norman, B., Davison, A., Neuckermans, J., Marcélis, L., Mortier, A., De Bundel, D., Ranganath, L., Martens, G., Vanhaecke, T., Gallagher, J. & De Kock, J., 17 apr 2020, blz. FRI284.Onderzoeksoutput: Poster
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Impact of nitisinone treatment and discontinuation on the metabolome of wild type and hereditary tyrosinemia type 1 mice
Colemonts-Vroninks, H., Norman, B., Davison, A., Neuckermans, J., Marcélis, L., Mortier, A., De Bundel, D., Ranganath, L., Martens, G., Vanhaecke, T., Gallagher, J. & De Kock, J., 2020, In: Journal of Hepatology. 73, 1, blz. S540-S541Onderzoeksoutput: Meeting abstract (Journal)
106 Citaten (Scopus) -
Inflammation Alters the Secretome and Immunomodulatory Properties of Human Skin-Derived Precursor Cells
De Kock, J., Rodrigues, R. M., Branson, S., Verhoye, L., Colemonts-Vroninks, H., Rombaut, M., Boeckmans, J., Neuckermans, J., Lequeue, S., Buyl, K., Merimi, M., Moussa Agha, D., De Boe, V., Lagneaux, L., Meuleman, P., Vanhaecke, T. & Najar, M., 8 apr 2020, In: Cells. 9, 4, 17 blz., 914.Onderzoeksoutput: Article › peer review
Open AccessBestand9 Citaten (Scopus)71 Downloads (Pure) -
2019
A robust bacterial assay for high-throughput screening of human 4-hydroxyphenylpyruvate dioxygenase inhibitors
Neuckermans, J., Mertens, A., Schwaneberg, U. & De Kock, J., 2 okt 2019, In: Scientific Reports. 9, 1, blz. 14145 11 blz., 14145.Onderzoeksoutput: Article › peer review
Open AccessBestand13 Citaten (Scopus)45 Downloads (Pure) -
Evaluation of the efficiency of CRE mRNA-induced recombination in human skin-derived mesenchymal stem cells
Rombaut, M., Colemonts-Vroninks, H., Neuckermans, J., Boeckmans, J., van Grunsven, L. A., Vanhaecke, T. & De Kock, J., 21 nov 2019.Onderzoeksoutput: Poster
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2018
Development of a high-throughput bacterial inhibition assay for human 4-hydroxyphenylpyruvate dioxygenase in the context of tyrosinemia type 1
Neuckermans, J., 2018, (Unpublished).Onderzoeksoutput: Poster
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Human skin-derived mesenchymal stromal cells do not rescue hereditary tyrosinemia type 1 mice after permanent nitisinone withdrawal
Colemonts-Vroninks, H., Laeremans, H., Claes, P., Neuckermans, J., Verhulst, S., van Grunsven, L. A., Martens, G., De Bundel, D., Vanhaecke, T. & De Kock, J., sep 2018, blz. S37-S219.Onderzoeksoutput: Poster
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2017
Establishment of the optimal mRNA electroporation protocol for human skin-derived mesenchymal stem cells
Neuckermans, J., 2017, (Unpublished).Onderzoeksoutput: Other
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ESTABLISHMENT OF THE OPTIMAL MRNA ELECTROPORATION PROTOCOL FOR HUMAN SKIN-DERIVED MESENCHYMAL STEM CELLS
Neuckermans, J., Branson, S., Heirman, C., Vanhaecke, T., Rogiers, V. & De Kock, J., 28 mrt 2017, (Unpublished).Onderzoeksoutput: Poster
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Establishment of the optimal mRNA electroporation protocol for human skin-derived mesenchymal stem cells.
Neuckermans, J., Branson, S., Vanhaecke, T. & De Kock, J., 2017.Onderzoeksoutput: Poster