Projecten per jaar
Vingerafdruk
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
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HERC66: 3D-CELLMAP: Onthullen van complexe celinteracties in weefsels door middel van 3D super-resolutie proteïne multiplex beeldvorming.
Movahedi, K., Rooman, I., Sermon, K., De Bundel, D., Fioravanti, A., Staels, W., Magez, S., Breckpot, K., De Kock, J., Laoui, D., Goyvaerts, C., Smolders, I., Van Ginderachter, J., Marcelino Rodrigues, R., De Leu, N., van Grunsven, L., Hernot, S., Peeters, E., Vanhaecke, T., De Veirman, K., Ruytinx, J., Van Schependom, J., Kortekaas, I. & Goossens, E.
1/05/24 → 31/05/28
Project: Fundamenteel
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OZR4288: Financiering MZW OZR: Snelle analyse en productie van eiwitten voor klinische translatie met behulp van Biacore en bioreactor systemen.
Devoogdt, N., Hernot, S., De Groof, T., Ballet, S., Stijlemans, B., Massie, A., Rooman, I., Keyaerts, M., Raes, G., De Kock, J., Breckpot, K., De Veirman, K. & Caveliers, V.
24/04/24 → 24/04/28
Project: Fundamenteel
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IOFPOC61: EVOStAR: een strategische toepasbaarheid en bedrijfsplan roadmap voor op EVOZymen-gebaseerde therapieën.
1/01/24 → 30/06/25
Project: Toegepast
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FWOTM1196: ExplorAKUre: Exploreren van genetisch ontwikkelde tyrosine ammonia lyase enzymen als mRNA therapie voor alkaptonurie
1/11/23 → 31/10/27
Project: Fundamenteel
Onderzoeksoutput
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A robust high-throughput screening system to assess bacterial tyrosine ammonia lyase activity in the context of tyrosine inherited metabolic disorders
Nulmans, I., Laga, C. A., Salvi, N. S., Desmet, L., Lequeue, S., Neuckermans, J., Schwaneberg, U. & De Kock, J., 27 sep 2024, In: Scientific reports. 14, 1, 1 blz., 22175.Onderzoeksoutput: Article › peer review
Open Access -
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Carriage of multiple genetic risk factors for MASH stimulates an altered inflammatory secretome in a human stem cell-based in vitro model
Gatzios, A., Rombaut, M., De Kock, J., De Win, D., Heymans, A., Rogiers, V., Rodrigues, R., Boeckmans, J. & Vanhaecke, T., 23 sep 2024, The Liver Meeting: 2024 Abstracts. Wolters Kluwer Health, Vol. 80(Suppl. 1). blz. S35-S35 1 blz. 53Onderzoeksoutput: Meeting abstract (Book)
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Exploring genetic predisposition for anti-MASH drug response in a human stem cell-based in vitro model
Gatzios, A., Rombaut, M., De Kock, J., De Win, D., Heymans, A., Rogiers, V., Rodrigues, R., Boeckmans, J. & Vanhaecke, T., 19 sep 2024, blz. 18. 18 blz.Onderzoeksoutput: Poster
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Hepatic programming of human skin-derived precursor cells into functional hepatocyte-like cells as a novel liver-based in vitro model
Stinckens, M., Rombaut, M., Gatzios, A., Rodrigues, R., Vanhaecke, T. & De Kock, J., 19 sep 2024, (Unpublished).Onderzoeksoutput: Poster
Prijzen
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33. Forschungspreises zur Förderung methodischer Arbeiten mit dem Ziel der Einschränkung und des Ersatzes von Tierversuchen
De Kock, Joery (Recipient), Marcelino Rodrigues, Robim (Recipient), Vanhaecke, Tamara (Recipient) & Rogiers, Vera (Recipient), 2014
Prijs: Prize (including medals and awards)
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FixAKUre: High-throughput screening of a chemical compound library with the aim to identify restabilizing compounds for homogentisate 1,2-dioxygenase enzyme variants in the context of rare disease alkaptonuria
De Kock, Joery (Recipient) & Lequeue, Sien (Recipient), 2022
Prijs: Prize (including medals and awards)
Activiteiten
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Genetic predisposition for anti-MASH drug response: a population-based in vitro study
Alexandra Gatzios (Speaker), Matthias Rombaut (Contributor), Joery De Kock (Contributor), Dinja De Win (Contributor), Anja Heymans (Contributor), Vera Rogiers (Contributor), Robim Marcelino Rodrigues (Contributor), Joost Boeckmans (Contributor) & Tamara Vanhaecke (Contributor)
5 jun 2024Activiteit: Talk or presentation at a conference
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Genetic predisposition for anti-MASH drug response: a population-based in vitro study
Alexandra Gatzios (Speaker), Matthias Rombaut (Contributor), Joery De Kock (Contributor), Dinja De Win (Contributor), Anja Heymans (Contributor), Vera Rogiers (Contributor), Robim Marcelino Rodrigues (Contributor), Joost Boeckmans (Contributor) & Tamara Vanhaecke (Contributor)
25 jun 2024Activiteit: Talk or presentation at a conference
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A stem cell-based in vitro test battery to predict liver steatotic potential of diverse chemicals
Anouk Verhoeven (Speaker), Alexandra Gatzios (Contributor), Robim Marcelino Rodrigues (Contributor), Julen Sanz Serrano (Contributor), Andres Tabernilla Garcia (Contributor), Joery De Kock (Contributor), Mathieu Vinken (Contributor) & Tamara Vanhaecke (Contributor)
4 jun 2024Activiteit: Talk or presentation at a conference
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Human hepatic in vitro models identify ANGPTL4, PDK4 and PLIN2 as potential pro-steatogenic mediators induced by elafibranor
Joost Boeckmans (Speaker), Alexandra Gatzios (Contributor), Anja Heymans (Contributor), Matthias Rombaut (Contributor), Vera Rogiers (Contributor), Joery De Kock (Contributor), Tamara Vanhaecke (Contributor) & Robim Marcelino Rodrigues (Contributor)
9 jun 2022Activiteit: Talk or presentation at a conference
Bestand -
Resmetirom reduces lipid load, restores THRB expression and prevents cell damage in a human stem cell based in vitro MAFLD model.
Alexandra Gatzios (Speaker), Robim Marcelino Rodrigues (Contributor), Joery De Kock (Contributor), Anouk Verhoeven (Contributor), Sara Sepehri (Contributor), Karolien Buyl (Contributor), Matthias Rombaut (Contributor), Vera Rogiers (Contributor), Joost Boeckmans (Contributor) & Tamara Vanhaecke (Contributor)
10 jun 2022Activiteit: Talk or presentation at a conference
Scriptie
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A quest to develop in vitro FAH and SLC7A11 knockout models, and methods to confirm them, in the context of hereditary tyrosinemia type1.
Auteur: Gül, A. & De Kock, J., 2024Begeleider: Del'Haye, G. (Advisor)
Scriptie/Masterproef: Master's Thesis
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Bepaling van de specifieke activiteit van cyclotron geproduceerd F18-fluoride en F18-gemerkt radiofarmacon
Auteur: Deprez, M., Caveliers, V., Blykers, A., De Kock, J. & Vander Heyden, Y., 10 jun 2015Scriptie/Masterproef: Master's Thesis
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Bijdrage tot het hepatisch herprogrammeren van humane huid-afgeleide hepatische progenitor cellen (hSKP-HPC) into human skin-derived hepatocytes (hSKP-HEP)
Auteur: Carini, L., Vanhaecke, T. & De Kock, J., 2023Begeleider: Vanhaecke, T. (Promotor)
Scriptie/Masterproef: Master's Thesis
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Development of a biosensor based high throughput screenings assay in the context of engineering human tyrosine ammonia lyase (TAL) enzymes to treat inborn errors of tyrosine metabolism.
Auteur: Soto, C., De Kock, J. & Desmet, L., 2024Scriptie/Masterproef: Master's Thesis
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Evaluatie van de efficiëntie van CRE mRNA-geïnduceerde recombinase in humane huidafgeleide mesenchymale stamcellen.
Auteur: Rombaut, M., Vanhaecke, T., De Kock, J. & Neuckermans, J., 2018Begeleider: Vanhaecke, T. (Promotor)
Scriptie/Masterproef: Master's Thesis