Projecten per jaar
Vingerafdruk
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
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IOF3035: B-LIVER 2.0 (Brusselse Alliantie voor Leveronderzoek & Valorisatie)
Vanhaecke, T., van Grunsven, L., De Kock, J., Vinken, M., Reynaert, H. & Van Goethem, F.
1/01/25 → 31/12/29
Project: Toegepast
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HERC66: 3D-CELLMAP: Onthullen van complexe celinteracties in weefsels door middel van 3D super-resolutie proteïne multiplex beeldvorming.
Movahedi, K., Rooman, I., Sermon, K., De Bundel, D., Fioravanti, A., Staels, W., Magez, S., Breckpot, K., De Kock, J., Laoui, D., Goyvaerts, C., Smolders, I., Van Ginderachter, J., Marcelino Rodrigues, R., De Leu, N., van Grunsven, L., Hernot, S., Peeters, E., Vanhaecke, T., De Veirman, K., Ruytinx, J., Van Schependom, J., Kortekaas, I. & Goossens, E.
1/05/24 → 31/05/28
Project: Fundamenteel
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OZR4288: Financiering MZW OZR: Snelle analyse en productie van eiwitten voor klinische translatie met behulp van Biacore en bioreactor systemen.
Devoogdt, N., Hernot, S., De Groof, T., Ballet, S., Stijlemans, B., Massie, A., Rooman, I., Keyaerts, M., Raes, G., De Kock, J., Breckpot, K., De Veirman, K. & Caveliers, V.
24/04/24 → 24/04/28
Project: Fundamenteel
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A robust bacterial high-throughput screening assay to identify pharmacological chaperones targeting human homogentisate 1,2-dioxygenase missense variants in alkaptonuria
Lequeue, S., Allach, H., Nulmans, I., Desmet, L., Salvi, N. S., Rombaut, M., Neuckermans, J., Schwaneberg, U., Vanhaecke, T. & Kock, J. D., okt. 2025, In: European Journal of Pharmacology. 1005, 13 blz., 178048.Onderzoeksoutput: Article › peer review
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Current state of the treatment landscape of phenylketonuria
Nulmans, I., Lequeue, S., Desmet, L., Neuckermans, J. & De Kock, J., 5 jun. 2025, In: Orphanet Journal of Rare Diseases. 20, 1, blz. 281 16 blz., 281.Onderzoeksoutput: Article › peer review
Open Access3 Citaten (Scopus) -
Development of a human cell-based test system to evaluate the catalytic activity of ammonia lyase enzymes for therapeutic use in aminoacidopathies
Nulmans, I., Salvi, N. & De Kock, J., 5 mrt. 2025, (Unpublished).Onderzoeksoutput: Poster
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Genetic predisposition for hepatic fat accumulation impacts the uptake of fatty acids through fatty acid translocase in a human stem cell-based in vitro model
Gatzios, A., Rombaut, M., De Kock, J., Verhoeven, A., De Win, D., Heymans, A., Rogiers, V., Rodrigues, R., Boeckmans, J. & Vanhaecke, T., 9 mei 2025, (Unpublished). 1 blz.Onderzoeksoutput: Poster
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Genetic predisposition for hepatic fat accumulation impacts the uptake of fatty acids through fatty acid translocase in a human stem cell-based in vitro model
Gatzios, A., Rombaut, M., De Kock, J., Verhoeven, A., De Win, D., Heymans, A., Rogiers, V., Rodrigues, R., Boeckmans, J. & Vanhaecke, T., mei 2025, Abstract Book of EASL Congress 2025. Elsevier, Vol. 82(S1). blz. S585-S586 2 blz. FRI-338Onderzoeksoutput: Meeting abstract (Book)
Open Access
Datasets
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Gene expression profiling of Fah- and Hgd-deficient mouse livers upon short-term nitisinone discontinuation
Neuckermans, J. (Creator), Claes, P. (Researcher), Heymans, A. (Researcher), Colemonts-Vroninks, H. (Project Member), Martens, G. (Project Member), Vanhaecke, T. (Supervisor) & De Kock, J. (Supervisor), NCBI Gene Expression Omnibus, 4 apr. 2023
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE225001
Dataset
Prijzen
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33. Forschungspreises zur Förderung methodischer Arbeiten mit dem Ziel der Einschränkung und des Ersatzes von Tierversuchen
De Kock, Joery (Recipient), Marcelino Rodrigues, Robim (Recipient), Vanhaecke, Tamara (Recipient) & Rogiers, Vera (Recipient), 2014
Prijs: Prize (including medals and awards)
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FixAKUre: High-throughput screening of a chemical compound library with the aim to identify restabilizing compounds for homogentisate 1,2-dioxygenase enzyme variants in the context of rare disease alkaptonuria
De Kock, Joery (Recipient) & Lequeue, Sien (Recipient), 2022
Prijs: Prize (including medals and awards)
Activiteiten
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Hepatic stellate cell activation: Improving models, biomarkers and therapeutic targets. (Evenement)
Vincent Merens (Presenter), Benoit Stijlemans (Jury), Leo van Grunsven (Member), Claudia Spits (Chair), Stefaan Verhulst (Member), Joery De Kock (Jury), Diana Al Delbany (Jury), Charlotte L. Scott (Jury) & Jerome Eeckhout (Jury)
27 okt. 2025Activiteit: Member of PhD committee
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A stem cell-based in vitro test battery to predict liver steatotic potential of diverse chemicals
Anouk Verhoeven (Speaker), Alexandra Gatzios (Contributor), Robim Marcelino Rodrigues (Contributor), Julen Sanz Serrano (Contributor), Andres Tabernilla Garcia (Contributor), Joery De Kock (Contributor), Mathieu Vinken (Contributor) & Tamara Vanhaecke (Contributor)
4 jun. 2024Activiteit: Talk or presentation at a conference
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Genetic predisposition for anti-MASH drug response: a population-based in vitro study
Alexandra Gatzios (Speaker), Matthias Rombaut (Contributor), Joery De Kock (Contributor), Dinja De Win (Contributor), Anja Heymans (Contributor), Vera Rogiers (Contributor), Robim Marcelino Rodrigues (Contributor), Joost Boeckmans (Contributor) & Tamara Vanhaecke (Contributor)
25 jun. 2024Activiteit: Talk or presentation at a conference
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Genetic predisposition for anti-MASH drug response: a population-based in vitro study
Alexandra Gatzios (Speaker), Matthias Rombaut (Contributor), Joery De Kock (Contributor), Dinja De Win (Contributor), Anja Heymans (Contributor), Vera Rogiers (Contributor), Robim Marcelino Rodrigues (Contributor), Joost Boeckmans (Contributor) & Tamara Vanhaecke (Contributor)
5 jun. 2024Activiteit: Talk or presentation at a conference
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Phd defence of Wissal Allaoui "Shedding light on the expression and function of neuromedin U in the brain" (Evenement)
Yvan Vander Heyden (Jury), Joery De Kock (Jury), Henry Heimberg (Jury), I Beets (Jury) & E Seuntjens (Jury)
7 sep. 2023Activiteit: Member of PhD committee
Scriptie
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A quest to develop in vitro FAH and SLC7A11 knockout models, and methods to confirm them, in the context of hereditary tyrosinemia type1.
Auteur: Gül, A. & De Kock, J., 2024Begeleider: Del'Haye, G. (Advisor)
Scriptie/Masterproef: Master's Thesis
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Bepaling van de specifieke activiteit van cyclotron geproduceerd F18-fluoride en F18-gemerkt radiofarmacon
Auteur: Deprez, M., Caveliers, V., Blykers, A., De Kock, J. & Vander Heyden, Y., 10 jun. 2015Scriptie/Masterproef: Master's Thesis
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Bijdrage tot het hepatisch herprogrammeren van humane huid-afgeleide hepatische progenitor cellen (hSKP-HPC) into human skin-derived hepatocytes (hSKP-HEP)
Auteur: Carini, L., Vanhaecke, T. & De Kock, J., 2023Begeleider: Vanhaecke, T. (Promotor)
Scriptie/Masterproef: Master's Thesis
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Casting error prone PCR mutagenesis of 4-hydroxyphenylpyruvate dioxygenase to decrease its sensitivity towards nitisinone
Auteur: Neuckermans, J., De Kock, J. & Cassar, J., 2019Scriptie/Masterproef: Master's Thesis
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Characterization of the cellular damage in the FRG mouse model of hereditary tyrosinemia type 1 after withdrawal of the orphan drug NTBC
Auteur: Neuckermans, J., De Kock, J. & Nysten, L., 2017Scriptie/Masterproef: Master's Thesis