Projecten per jaar
Vingerafdruk
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Projecten
- 1 Afgelopen
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Structural and functional insights in Synaptojanin1 and its implication in disease
Martin, E., Paesmans, J., Berghmans, M., Galicia Diaz Santana, C. & Versées, W., 13 mei 2024, (Unpublished).Onderzoeksoutput: Poster
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Allosteric modulation of the GTPase activity of a bacterial LRRK2 homolog by conformation-specific Nanobodies
Leemans, M., Galicia, C., Deyaert, E., Daems, E., Krause, L., Paesmans, J., Pardon, E., Steyaert, J., Kortholt, A., Sobott, F., Klostermeier, D. & Versees, W., 17 apr 2020, In: Biochemical Journal. 477, 7, blz. 1203-1218 16 blz.Onderzoeksoutput: Article › peer review
Open AccessBestand11 Citaten (Scopus)67 Downloads (Pure) -
A structure of substrate-bound Synaptojanin1 provides new insights in its mechanism and the effect of disease mutations
Paesmans, J., Martin, E., Deckers, B., Berghmans, M., Sethi, R., Loeys, Y., Pardon, E., Steyaert, J., Verstreken, P., Galicia, C. & Versées, W., 22 dec 2020, In: eLife. 9, blz. 1-27 27 blz., e64922.Onderzoeksoutput: Article › peer review
Open AccessBestand9 Citaten (Scopus)124 Downloads (Pure) -
Compounds for treatment of intractable epilepsy and doors syndrome
Verstreken, P., Lüthy, K., Versées, W., Fischer, B. & Paesmans, J., 2019, Octrooi Nr. EP3503880Onderzoeksoutput: Patent
Datasets
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Crystal structure of the TLDc domain of Skywalker/TBC1D24 from Drosophila melanogaster
Versées, W. (Project Leader), Fischer, B. (Creator) & Paesmans, J. (Researcher), Protein Data Bank in Europe, 17 jul 2019
DOI: 10.2210/pdb6R82/pdb
Dataset
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Crystal structure of the 5-phosphatase domain of Synaptojanin1 bound to its substrate diC8-PI(3,4,5)P3 in complex with a nanobody.
Paesmans, J. (Creator), Versées, W. (Supervisor), Galicia Diaz Santana, C. (Creator) & Martin, E. (Creator), Protein Data Bank in Europe, 30 dec 2020
DOI: 10.2210/pdb7A17/pdb
Dataset
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Crystal structure of the 5-phosphatase domain of Synaptojanin1 in complex with a nanobody
Paesmans, J. (Creator), Versées, W. (Supervisor), Galicia Diaz Santana, C. (Creator) & Martin, E. (Creator), Protein Data Bank in Europe, 30 dec 2020
DOI: 10.2210/pdb7A0V/pdb
Dataset
Activiteiten
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EMBO Molecular Neurobiology workshop
Jone Paesmans (Speaker), Wim Versees (Contributor), Baptiste Fischer (Contributor), Patrik Verstreken (Contributor) & Kevin Lüthy (Contributor)
8 mei 2018 → 12 mei 2018Activiteit: Talk or presentation at a workshop/seminar
Scriptie
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Karakterisering van domein- en conformatie-specifieke Nanobodies gericht tegen een bacterieel homoloog van het LRRK2-eiwit
Auteur: Paesmans, J., 30 jun 2014Begeleider: Versees, W. (Promotor), Steyaert, J. (Co-promotor), Muyldermans, S. (Jury) & Vanderheyden, P. (Jury)
Scriptie/Masterproef: Master's Thesis
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Unraveling the structure and function of the synaptic proteins TBC1D24 and Synaptojanin1 and their role in neurological disorders
Auteur: Paesmans, J., Versées, W., Ballet, S., Brunner, J., Smolders, I., Greggio, E. & Ismail, S., 29 jun 2021Scriptie/Masterproef: Doctoral Thesis