Projecten per jaar
Persoonlijk profiel
Expertise
- Basic and translational research in multiple myeloma
- Research for therapies, targeting the myeloma cell in its microenvironment
- Study of functional interaction between the cancer cell and its microenvironment using microarray, realtime PCR and FACS analysis and westernblotting.
- Investigate the influence of histon deacetylase inhibitors (HDAC-I) in 5TMM models.
Vingerafdruk
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
-
BASGO38: OZR Basisfinanciering voor Grote Onderzoeksgroepen - TORC
1/01/24 → 31/12/29
Project: Fundamenteel
-
SRP84: SRP-Onderzoekszwaartepunt: PACT: multi-omics Profilering van T-cellen om Adoptieve Cel Therapie te verbeteren
Vanderkerken, K., Breckpot, K. & Menu, E.
1/11/22 → 31/10/27
Project: Fundamenteel
-
FWOAL1045: Gepersonaliseerde therapie gericht tegen het AXL eiwit voor de behandeling van acute myeloide leukemie en multipel myeloom
De Veirman, K., Devoogdt, N. & Vanderkerken, K.
1/01/22 → 31/12/25
Project: Fundamenteel
-
AIIFUND22: Een nieuwe strategie in het uitroeien van residuele kankercellen in multipel myeloom.
Vanderkerken, K. & De Veirman, K.
28/09/17 → …
Project: Fundamenteel
Onderzoeksoutput
-
Correction to: Bortezomib-releasing silica-collagen xerogels for local treatment of osteolytic bone- and minimal residual disease in multiple myeloma (Journal of Hematology & Oncology, (2024), 17, 1, (128), 10.1186/s13045-024-01636-4)
Hose, D., Ray, S., Rößler, S., Thormann, U., Schnettler, R., de Veirman, K., Khassawna, T. E., Heiss, C., Hild, A., Zahner, D., Alagboso, F., Henss, A., Beck, S., Emde-Rajaratnam, M., Burhenne, J., Bamberger, J., Menu, E., de Bruyne, E., Gelinsky, M., Kampschulte, M., & 6 anderen , 24 jan. 2025, In: Journal of Hematology & Oncology. 18, 1, 1 blz., 11.Onderzoeksoutput: Comment/debate
Open Access -
Targeting MAT2A alters the methylation landscape and DNA damage response in Multiple Myeloma, revealing novel combination strategies.
Van Hemelrijck, L. A., Wang, Y., Muylaert, C., Olsen, C., De Veirman, K., Vanderkerken, K., Menu, E. & De Bruyne, E., 7 feb. 2025. 1 blz.Onderzoeksoutput: Poster
-
The de novo DNA methyltransferase 3B is a novel epigenetic regulator of MYC in multiple myeloma, representing a promising therapeutic target to counter relapse
Muylaert, C., Van Hemelrijck, L. A., Van der Vreken, A., Heestermans, R., Satilmis, H., Verheye, E., Alaterre, E., Olsen, C., De Beule, N., De Veirman, K., Menu, E., Vanderkerken, K., Moreaux, J. & De Bruyne, E., 17 apr. 2025, In: Journal of Experimental & Clinical Cancer Research. 44, 1, 18 blz., 125.Onderzoeksoutput: Article › peer review
Open Access1 Citaat (Scopus) -
Activated cDCs by anti-CD40 agonist therapy induce anti-tumor effectsin Multiple Myeloma
Verheye, E., Kancheva, D., Satilmis, H., Vandewalle, N., Fan, R., Bardet, P., Clappaert, E., Vanderkerken, K., De Veirman, K. & Laoui, D., 2024, (Unpublished).Onderzoeksoutput: Poster
-
Adrenergic signaling activates the tumor immune microenvironment in Multiple Myeloma
Satilmis, H., Verheye, E., Vandewalle, N., De Bruyne, E., Menu, E., Vanderkerken, K. & De Veirman, K., 30 mei 2024, (Unpublished).Onderzoeksoutput: Poster
Datasets
-
Dataset of AXL-specific single domain antibodies show diagnostic potential and anti-tumor activity in Acute Myeloid Leukemia
Vandewalle, N. (Creator), Satilmis, H. (Creator), Verheye, E. (Creator), Wang, Y. (Creator), De Groof, T. (Creator), Bridoux, J. (Creator), Kerre, T. (Creator), De Beule, N. (Creator), De Becker, A. (Creator), De Bruyne, E. (Creator), Menu, E. (Creator), Vanderkerken, K. (Creator), Breckpot, K. (Creator), Devoogdt, N. (Creator) & De Veirman, K. (Creator), Theranostics, 15 apr. 2024
DOI: 10.7150/thno.91456, https://zenodo.org/records/15111364
Dataset
-
A single-cell transcriptomic map of the murine and human multiple myeloma immune microenvironment across disease stages
Laoui, D. (Creator), Kancheva, D. (Creator), Satilmis, H. (Creator), Vandewalle, N. (Creator), Fan, R. (Creator), Bardet, P. (Creator), Clappaert, E. (Creator), Verstaen, K. (Creator), De Becker, A. (Creator), Vanderkerken, K. (Creator) & De Veirman, K. (Creator), NCBI Gene Expression Omnibus, 14 nov. 2024
Dataset
Prijzen
-
Award of the Association for International Cancer Research
Vanderkerken, Karin (Recipient), 2004
Prijs: Prize (including medals and awards)
-
Best Poster Presentation BHS 2025
Van Hemelrijck, Lien Ann (Recipient), Wang, Yanmeng (Recipient), Muylaert, Catharina (Recipient), Olsen, Catharina (Recipient), De Veirman, Kim (Recipient), Vanderkerken, Karin (Recipient), Menu, Eline (Recipient) & De Bruyne, Elke (Recipient), 7 feb. 2025
Prijs: Prize (including medals and awards)
-
Hilde Bruers Award
Vanderkerken, Karin (Recipient), 29 feb. 2008
Prijs: Prize (including medals and awards)
-
Junior Award Multiple Myeloma Research Foundation
Vanderkerken, Karin (Recipient), 2001
Prijs: Prize (including medals and awards)
-
Laureaat Belgische Federatie tegen Kanker
Vanderkerken, Karin (Recipient), 2004
Prijs: Prize (including medals and awards)
Activiteiten
-
AXL-specific single domain antibodies show diagnostic potential and anti-tumor activity in Acute Myeloid Leukemia
Niels Vandewalle (Presenter), Hatice Satilmis (Contributor), Emma Verheye (Contributor), Yanmeng Wang (Contributor), Timo De Groof (Contributor), Nathan De Beule (Contributor), Tessa kerre (Contributor), Nathan De Beule (Contributor), Ann De Becker (Contributor), Elke De Bruyne (Contributor), Eline Menu (Contributor), Karin Vanderkerken (Contributor), Karine Breckpot (Contributor), Nick Devoogdt (Contributor) & Kim De Veirman (Contributor)
12 mrt. 2024Activiteit: Talk or presentation at a conference
-
Mapping the immune heterogeneity within the myeloma microenvironment using single-cell transcriptomics
Emma Verheye (Speaker), Rong Fan (Contributor), Hatice Satilmis (Contributor), Niels Vandewalle (Contributor), Pauline Bardet (Contributor), Emile Clappaert (Contributor), Daliya Kancheva (Contributor), Elke De Bruyne (Contributor), Karin Vanderkerken (Contributor), Kim De Veirman (Contributor) & Damya Laoui (Contributor)
3 feb. 2023Activiteit: Talk or presentation at a conference
-
AXL targeting using Bemcentinib increases chemosensitivity in Acute Myeloid Leukemia
Niels Vandewalle (Speaker), Laura Meysman (Contributor), Nathan De Beule (Contributor), Ann De Becker (Contributor), Hatice Satilmis (Contributor), Emma Verheye (Contributor), Rong Fan (Contributor), Elke De Bruyne (Contributor), Eline Menu (Contributor), Karin Vanderkerken (Contributor), Karine Breckpot (Contributor), Nick Devoogdt (Contributor) & Kim De Veirman (Contributor)
3 feb. 2023Activiteit: Talk or presentation at a conference
-
Combining dual G9a/DNMTs epigenetic inhibition and immunotherapy to treat metastatic melanoma
Lien De Beck (Speaker), Robin Maximilian Awad (Contributor), Yannick De Vlaeminck (Contributor), Veronica Basso (Contributor), Noelia Casares (Contributor), Stefaan Verhulst (Contributor), Edurne San José-Enériz (Contributor), Kirsten De Ridder (Contributor), Cleo Goyvaerts (Contributor), Ken Maes (Contributor), Karin Vanderkerken (Contributor), Xabier Agirre (Contributor), Filipe Prosper (Contributor), Juan José Lasarte (Contributor), Anna Mondino (Contributor) & Karine Breckpot (Contributor)
11 feb. 2021Activiteit: Talk or presentation at a conference
-
Lunchdebat Gelijkheidsactieplan
Gina Rossi (Participant) & Karin Vanderkerken (Participant)
19 nov. 2019Activiteit: Other