Projecten per jaar
Persoonlijk profiel
Expertise
- Basic and translational research in multiple myeloma
- Research for therapies, targeting the myeloma cell in its microenvironment
- Study of functional interaction between the cancer cell and its microenvironment using microarray, realtime PCR and FACS analysis and westernblotting.
- Investigate the influence of histon deacetylase inhibitors (HDAC-I) in 5TMM models.
Vingerafdruk
Verdiep u in de onderzoeksgebieden waarop Karin Vanderkerken actief is. Deze onderwerplabels komen uit het werk van deze persoon. Samen vormen ze een unieke vingerafdruk.
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
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SRP84: SRP-Onderzoekszwaartepunt: PACT: multi-omics Profilering van T-cellen om Adoptieve Cel Therapie te verbeteren
Vanderkerken, K., Breckpot, K. & Menu, E.
1/11/22 → 31/10/27
Project: Fundamenteel
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FWOAL1045: Gepersonaliseerde therapie gericht tegen het AXL eiwit voor de behandeling van acute myeloide leukemie en multipel myeloom
De Veirman, K., Devoogdt, N. & Vanderkerken, K.
1/01/22 → 31/12/25
Project: Fundamenteel
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EU639: EUTOPIA - Transformatie van onderzoek en innovatie (TRAIN)
1/01/21 → 31/12/23
Project: Fundamenteel
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SRP48: Strategic Research Programme: Cancer Cell Targeting in Myeloma and Melanoma (MyMe)
Vanderkerken, K., Thielemans, K., Vanderkerken, K. & Breckpot, K.
1/11/17 → 31/10/24
Project: Fundamenteel
Onderzoeksoutput
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Metformin confers sensitisation to syrosingopine in multiple myeloma cells by metabolic blockage and inhibition of protein synthesis
Van der Vreken, A., Oudaert, I., Ates, G., Faict, S., Vlummens, P., Satilmis, H., Fan, R., Maes, A., Massie, A., De Veirman, K., De Bruyne, E., Vanderkerken, K. & Menu, E., 28 mrt 2023, In: Journal of pathology. 260, 2, blz. 112-123 12 blz.Onderzoeksoutput: Article › peer review
1 Citaat (Scopus) -
S-adenosylmethionine biosynthesis is a targetable metabolic vulnerability in multiple myeloma
Wang, Y., Muylaert, C., Wyns, A., Vlummens, P., De Veirman, K., Vanderkerken, K., Zaal, E., Berkers, C., Moreaux, J., De Bruyne, E. & Menu, E., 20 jul 2023, (E-pub ahead of print) In: Haematologica.Onderzoeksoutput: Article › peer review
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Targeting DNMT3B impairs multiple myeloma cell proliferation and clonogenic capacity and enhances sensitivity to standard of care agents.
Muylaert, C., Van Hemelrijck, L. A., Alaterre, E., Robert, N., Requirand, G., De Veirman, K., Menu, E., Vanderkerken, K., Moreaux, J. & De Bruyne, E., sep 2023.Onderzoeksoutput: Poster
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Targeting stromal cell sialylation reverses T cell-mediated immunosuppression in the tumor microenvironment
Egan, H., Treacy, O., Lynch, K., Leonard, N. A., O'Malley, G., Reidy, E., O'Neill, A., Corry, S. M., De Veirman, K., Vanderkerken, K., Egan, L. J., Ritter, T., Hogan, A. M., Redmond, K., Peng, L., Che, J., Gatlin, W., Jayaraman, P., Sheehan, M., Canney, A. & 5 anderen, , mei 2023, In: Cell Reports. 42, 5, 1 blz., 112475.Onderzoeksoutput: Article › peer review
Open AccessBestand1 Citaat (Scopus)1 Downloads (Pure) -
Targeting the β2 -adrenergic receptor increases chemosensitivity in multiple myeloma by induction of apoptosis and modulating cancer cell metabolism
Satilmis, H., Verheye, E., Vlummens, P., Oudaert, I., Vandewalle, N., Fan, R., Knight, J., De Beule, N., Ates, G., Massie, A., Moreaux, J., Maes, A., De Bruyne, E., Vanderkerken, K., Menu, E., Sloan, E. & De Veirman, K., jan 2023, In: Journal of pathology. 259, 1, blz. 69–80 12 blz.Onderzoeksoutput: Article › peer review
Open AccessBestand2 Citaten (Scopus)1 Downloads (Pure)
Prijzen
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Award of the Association for International Cancer Research
Vanderkerken, Karin (Recipient), 2004
Prijs: Prize (including medals and awards)
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Hilde Bruers Award
Vanderkerken, Karin (Recipient), 29 feb 2008
Prijs: Prize (including medals and awards)
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Junior Award Multiple Myeloma Research Foundation
Vanderkerken, Karin (Recipient), 2001
Prijs: Prize (including medals and awards)
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Laureaat Belgische Federatie tegen Kanker
Vanderkerken, Karin (Recipient), 2001
Prijs: Prize (including medals and awards)
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Laureaat Belgische Federatie tegen Kanker
Vanderkerken, Karin (Recipient), 2004
Prijs: Prize (including medals and awards)
Activiteiten
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Mapping the immune heterogeneity within the myeloma microenvironment using single-cell transcriptomics
Emma Verheye (Speaker), Rong Fan (Contributor), Hatice Satilmis (Contributor), Niels Vandewalle (Contributor), Pauline Bardet (Contributor), Emile Clappaert (Contributor), Daliya Kancheva (Contributor), Elke De Bruyne (Contributor), Karin Vanderkerken (Contributor), Kim De Veirman (Contributor) & Damya Laoui (Contributor)
3 feb 2023Activiteit: Talk or presentation at a conference
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AXL targeting using Bemcentinib increases chemosensitivity in Acute Myeloid Leukemia
Niels Vandewalle (Speaker), Laura Meysman (Contributor), Nathan De Beule (Contributor), Ann De Becker (Contributor), Hatice Satilmis (Contributor), Emma Verheye (Contributor), Rong Fan (Contributor), Elke De Bruyne (Contributor), Eline Menu (Contributor), Karin Vanderkerken (Contributor), Karine Breckpot (Contributor), Nick Devoogdt (Contributor) & Kim De Veirman (Contributor)
3 feb 2023Activiteit: Talk or presentation at a conference
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Combining dual G9a/DNMTs epigenetic inhibition and immunotherapy to treat metastatic melanoma
Lien De Beck (Speaker), Robin Maximilian Awad (Contributor), Yannick De Vlaeminck (Contributor), Veronica Basso (Contributor), Noelia Casares (Contributor), Stefaan Verhulst (Contributor), Edurne San José-Enériz (Contributor), Kirsten De Ridder (Contributor), Cleo Goyvaerts (Contributor), Ken Maes (Contributor), Karin Vanderkerken (Contributor), Xabier Agirre (Contributor), Filipe Prosper (Contributor), Juan José Lasarte (Contributor), Anna Mondino (Contributor) & Karine Breckpot (Contributor)
11 feb 2021Activiteit: Talk or presentation at a conference
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MCL1 Inhibitors in Multiple Myeloma
Kim De Veirman (Contributor), Karin Vanderkerken (Speaker), Elke De Bruyne (Contributor) & Eline Menu (Contributor)
13 nov 2019Activiteit: Talk or presentation at a conference
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Lunchdebat Gelijkheidsactieplan
Gina Rossi (Participant) & Karin Vanderkerken (Participant)
19 nov 2019Activiteit: Other