Projecten per jaar
Persoonlijk profiel
Expertise
- Manufacturing and screening of monoclonal antibodies against human cell membranes and proteins. Sorting cells on FACS-sorter. DNA analysis using gen probes for clinical purposes. Orders for third parties have been executed. Delays may be discussed and depend on the demand.
- Hematology & Immunobiology
- Generation of mouse and human dendritic cells Genetic modification of dendritic cells
- Gene transfer technology (adenovirus, retrovirus, lentivirus) Non viral transfer techniques (RNA electroporation)
Vingerafdruk
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
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VOPPU95: VOPPU95 - Prijs Kankeronderzoek - Wout De Mey
Breckpot, K., Thielemans, K. & de Mey, W.
1/01/21 → 30/06/21
Project: Fundamenteel
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ANI216: Prioritering van neoantigenen door de combinatie van in silico onderzoek en massaspectrometrie.
1/01/19 → 31/12/22
Project: Fundamenteel
Onderzoeksoutput
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An mRNA mix redirects dendritic cells towards an antiviral program, inducing anticancer cytotoxic stem cell and central memory CD8+ T cells
de Mey, W., Locy, H., De Ridder, K., De Schrijver, P., Autaers, D., Lakdimi, A., Esprit, A., Franceschini, L., Thielemans, K., Verdonck, M. & Breckpot, K., 4 mrt 2023, In: Frontiers in Immunology. 14, 10 blz., 1111523.Onderzoeksoutput: Article › peer review
Open AccessBestand6 Citaten (Scopus)31 Downloads (Pure) -
Assessment of Human SARS CoV-2-Specific T-Cell Responses Elicited In Vitro by New Computationally Designed mRNA Immunogens: COVARNA
Esteban, I., Pastor-Quinones, C., Usero, L., Aurrecoechea, E., Franceschini, L., Esprit, A., Gelpi, J. L., Martinez-Jimenez, F., Lopez-Biga, N., Breckpot, K., Thielemans, K., Leal, L., Gomez, C. E., Sistere-Oro, M., Meyerhans, A., Esteban, M., Alonso, M. J., Garcia, F. & Plana, M., 22 dec 2023, In: Vaccines. 12, 1, blz. 15-30 16 blz., 15.Onderzoeksoutput: Article › peer review
Open AccessBestand6 Downloads (Pure) -
Challenges in neoantigen-directed therapeutics
Lybaert, L., Lefever, S., Fant, B., Smits, E., De Geest, B., Breckpot, K., Dirix, L., Feldman, S. A., van Criekinge, W., Thielemans, K., van der Burg, S. H., Ott, P. A. & Bogaert, C., 9 jan 2023, In: Cancer Cell. 41, 1, blz. 15-40 26 blz.Onderzoeksoutput: Article › peer review
Open AccessBestand50 Citaten (Scopus)96 Downloads (Pure) -
Assessing Tumor-Infiltrating Lymphocytes in Breast Cancer: A Proposal for Combining Immunohistochemistry and Gene Expression Analysis to Refine Scoring
Locy, H., Verhulst, S., Cools, W., Waelput, W., Brock, S., Cras, L., Schiettecatte, A., Jonckheere, J., van Grunsven, L. A., Vanhoeij, M., Thielemans, K. & Breckpot, K., 11 feb 2022, In: Frontiers in Immunology. 13, blz. 1-13 13 blz., 794175.Onderzoeksoutput: Article › peer review
Open AccessBestand14 Citaten (Scopus)67 Downloads (Pure) -
A synthetic DNA template for fast manufacturing of versatile single epitope mRNA
de Mey, W., De Schrijver, P., Autaers, D., Pfitzer, L., Fant, B., Locy, H., Esprit, A., Lybaert, L., Bogaert, C., Verdonck, M., Thielemans, K., Breckpot, K. & Franceschini, L., 13 sep 2022, In: Molecular Therapy Nucleic Acids. 29, blz. 943-954 12 blz.Onderzoeksoutput: Article › peer review
Open AccessBestand13 Citaten (Scopus)47 Downloads (Pure)
Datasets
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MOESM2 of Intranodal administration of mRNA encoding nucleoprotein provides cross-strain immunity against influenza in mice
Saelens, X. (Creator), Ysenbaert, T. (Creator), Schepens, B. (Creator), Heirman, C. (Creator), Thielemans, K. (Creator), Christopoulou, I. (Creator), Van Hoecke, L. (Creator) & Aerts, J. L. (Creator), Springer, 1 jan 2019
DOI: 10.6084/m9.figshare.9109040, http://10.1186/s12967-019-1991-3
Dataset
Activiteiten
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Unknown (Externe Organisatie)
Kris Thielemans (Member)
2012 → 2015Activiteit: Membership of external research organisation
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Unknown (Externe Organisatie)
Kris Thielemans (Member)
10 okt 2010 → …Activiteit: Membership of external research organisation
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Unknown (Externe Organisatie)
Kris Thielemans (Member)
2009 → …Activiteit: Membership of external research organisation
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Unknown (Externe Organisatie)
Kris Thielemans (Member)
2009Activiteit: Membership of external research organisation
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Stanford University (Externe Organisatie)
Kris Thielemans (Member)
2008 → …Activiteit: Membership of external research organisation
Knipsels
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Sanofi Podcast: Therapeutic RNA vaccines in cancer immunotherapy
Karine Breckpot & Kris Thielemans
29/03/23
1 Mediabijdrage
Pers / media: !!Public Engagement Activities
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Vlaamse overheid pompt 2 miljoen euro in darmkankervaccin
Karine Breckpot & Kris Thielemans
21/02/20
1 item van Media-aandacht
Pers / media: !!Other
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Vlaamse overheid pompt 2 miljoen euro in darmkankervaccin
Karine Breckpot & Kris Thielemans
21/02/20
1 item van Media-aandacht
Pers / media: !!Other
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Darmkanker - Vlaanderen injecteert 2 miljoen euro
Karine Breckpot & Kris Thielemans
20/02/20
1 item van Media-aandacht
Pers / media: !!Other
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Darmkanker: Vlaanderen injecteert 2 miljoen euro
Karine Breckpot & Kris Thielemans
20/02/20
1 item van Media-aandacht
Pers / media: !!Other
Scriptie
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Plasmid engineering to enhance stability and translatability for MRNA-based immunotherapy
Auteur: Cappelle, C. A., Thielemans, K. & Franceschini, L., 2019Scriptie/Masterproef: Master's Thesis