Projecten per jaar
Persoonlijk profiel
Expertise
Marius Regin graduated in Biomedical Sciences at the VUB in june 2018 with great distinction. During his master thesis at REGE he validated and implemented simultaneous genomic and transcriptomic sequencing of single human embryonic stem cells. Immediately after obtaining his master degree he started his PhD project under supervision of Prof. Sermon and Prof. Spits on the search for the origin of chromosomal abnormalities in human preimplantation embryos. Furthermore, he has ongoing collaborations with the KU Leuven and the Karolinska Institutet (Sweden).
Vingerafdruk
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Projecten
- 1 Afgelopen
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FWOTM968: De zoektocht naar de oorsprong van chromosomale afwijkingen in menselijke pre-implantatie-embryo's
Sermon, K., Spits, C. & Regin, M.
1/10/19 → 31/10/23
Project: Fundamenteel
Onderzoeksoutput
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Children born after assisted reproduction more commonly carry a mitochondrial genotype associating with low birthweight
Spits, C., Mertens, J., Belva, F., van Montfoort, A. PA., Regin, M., Zambelli, F., Seneca, S., Couvreu De Deckersberg, E., Bonduelle, M-L., Tournaye, H., Stouffs, K., Barbé, K., Smeets, B., Van De Velde, H., Sermon, K. & Blockeel, C., 9 feb 2024, In: Nature Communications. 15, 1, 16 blz., 1232 .Onderzoeksoutput: Article › peer review
Open AccessBestand2 Citaten (Scopus)6 Downloads (Pure) -
De Novo Cancer Mutations Frequently Associate with Recurrent Chromosomal Abnormalities during Long-Term Human Pluripotent Stem Cell Culture
Delbany, D. A., Ghosh, M. S., Krivec, N., Huyghebaert, A., Regin, M., Duong, M. C., Lei, Y., Sermon, K., Olsen, C. & Spits, C., 21 aug 2024, In: Cells. 13, 16, 12 blz., 1395.Onderzoeksoutput: Article › peer review
Open AccessBestand3 Downloads (Pure) -
Gain of 1q confers an MDM4-driven growth advantage to undifferentiated and differentiating hESC while altering their differentiation capacity
Krivec, N., Couvreu De Deckersberg, E., Lei, Y., Al Delbany, D., Regin, M., Verhulst, S., van Grunsven, L. A., Sermon, K. & Spits, C., 21 nov 2024, In: Cell Death and Disease. 15, 14 blz., 852.Onderzoeksoutput: Article › peer review
Open Access -
Regulators of cell fate decisions in human pre-implantation embryos
Regin, M., 2024, Crazy Copy Center Productions. 195 blz.Onderzoeksoutput: PhD Thesis
Open AccessBestand292 Downloads (Pure) -
SALL3 mediates the loss of neuroectodermal differentiation potential in human embryonic stem cells with chromosome 18q loss
Spits, C., Lei, Y., Al Delbany, D., Krivec, N., Regin, M., Couvreu De Deckersberg, E., Janssens, C., Ghosh, M. & Sermon, K., 9 apr 2024, In: Stem Cell Reports. 19, 4, blz. 562-578 17 blz.Onderzoeksoutput: Article › peer review
Open Access4 Citaten (Scopus)
Datasets
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De Novo Cancer Mutations Frequently Associate with Recurrent Chromosomal Abnormalities during Long-Term Human Pluripotent Stem Cell Culture
Al Delbany, D. (Creator), Ghosh, M. (Creator), Krivec, N. (Creator), Huyghebaert, A. (Creator), Regin, M. (Creator), Duong, C. M. (Creator), Lei, Y. (Creator), Sermon, K. (Creator), Olsen, C. (Creator) & Spits, C. (Creator), OSF, 2024
Dataset
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Lineage segregation in human pre-implantation embryos is specified by YAP1 and TEAD1
Spits, C. (Creator), Verloes, A. (Creator), Regin, M. (Creator) & Van De Velde, H. (Creator), OSF, 11 dec 2024
DOI: 10.17605/OSF.IO/NUHZM, https://osf.io/nuhzm/
Dataset
Activiteiten
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Regulators of cell fate decisions in human pre-implantation embryos (Evenement)
Luc Leyns (Jury), Marius Regin (Presenter), Karen Sermon (Supervisor) & Claudia Spits (Supervisor)
28 mrt 2024Activiteit: Member of PhD committee
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Aneuploidy induces proteotoxic stress and autophagy-mediated apoptosis in human preimplantation embryos
Marius Regin (Speaker), Edouard Couvreu De Deckersberg (Contributor), Yves Guns (Contributor), Pieter Verdyck (Contributor), Greta Verheyen (Contributor), Hilde Van De Velde (Contributor), Claudia Spits (Contributor) & Karen Sermon (Contributor)
1 jul 2021Activiteit: Talk or presentation at a conference
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Mitochondrial DNA mosaicism in early human development
Joke Mertens (Speaker), Marius Regin (Contributor), Neelke De Munck (Contributor), Edouard Couvreu De Deckersberg (Contributor), Christophe Blockeel (Contributor), Herman Tournaye (Contributor), Hilde Van De Velde (Contributor), Karen Sermon (Contributor) & Claudia Spits (Contributor)
17 sep 2021Activiteit: Talk or presentation at a conference
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Aneuploidy induces proteotoxic stress and autophagy-mediated apoptosis in human preimplantation embryos
Marius Regin (Speaker), Yingnan Lei (Contributor), Edouard Couvreu De Deckersberg (Contributor), Yves Guns (Contributor), Pieter Verdyck (Contributor), Greta Verheyen (Contributor), Hilde Van De Velde (Contributor), Claudia Spits (Contributor) & Karen Sermon (Contributor)
26 nov 2021 → 27 nov 2021Activiteit: Talk or presentation at a conference
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Genomics and Embryo Selection in Assisted Reproduction
Marius Regin (Participant)
12 sep 2019 → 14 sep 2019Activiteit: Participation in workshop, seminar