Projecten per jaar
Persoonlijk profiel
Expertise
Marleen Keyaerts obtained her PhD in preclinical research about molecular imaging and therapy at the ICMI lab of the VUB. She obtained a senior clinical investigator scholarship of the Research Foundation Flanders in 2013. Marleen now combines her clinical work as a nuclear medicine physician with basic and translational research at the ICMI lab. One of her major goals is the clinical translation of new radiopharmaceuticals for imaging and therapy. She also focuses on cancer immunotherapy, with a special interest in immune checkpoint blockade therapy and targeted radionuclide therapy.
Vingerafdruk
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
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HERC59: PET camera voor beeldvorming van kleine proefdieren
Devoogdt, N., Raes, G., Lahoutte, T., Van Ginderachter, J., Caveliers, V., Keyaerts, M., Hernot, S. & D'Huyvetter, M.
1/05/22 → 30/04/26
Project: Fundamenteel
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EUAR14: H2020: Immune-Image
Lahoutte, T., Devoogdt, N. & Keyaerts, M.
1/10/19 → 30/09/24
Project: Toegepast
Onderzoeksoutput
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Accepted poster session at ImmunoRad 2023: Targeted alpha therapy using Actinium-225 radiolabeled single domain antibodies induces antigen-specific immune responses and instills immunomodulation both systemically and at the tumor microenvironment
Ertveldt, T., Krasniqi, A., Ceuppens, H., Puttemans, J., Dekempeneer, Y., De Jonghe, K., de Mey, W., Lecocq, Q., De Vlaeminck, Y., Awad, R. M., Goyvaerts, C., De Veirman, K., Morgenstern, A., Bruchertseifer, F., Keyaerts, M., Devoogdt, N., D'Huyvetter, M. & Breckpot, K., 27 sep 2023.Onderzoeksoutput: Poster
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A comparison of [68Ga]Ga-NOTA-anti-HER2-sdAb PET/CT with [18F]FDG-PET/CT in breast carcinoma patients.
Gondry, O., Xavier, C., Heemskerk, J., Raes, L. A. J., Debacker, J., De Geeter, F., Fontaine, C., Vanhoeij, M., Aspeslagh, S., Joris, S., De Grève, J., Verfaillie, G., Luyten, I., De Mey, L., Vandenbroucke, F., Waelput, W., Glorieus, K., Bourgeois, S., Cousaert, J., Vaneycken, I. & 5 anderen, , 2023.Onderzoeksoutput: Unpublished abstract
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Development and Validation of a Predictive Model for Metastatic Melanoma Patients Treated with Pembrolizumab Based on Automated Analysis of Whole-Body [18F]FDG PET/CT Imaging and Clinical Features
Dirks, I., Keyaerts, M., Dirven, I., Neyns, B. & Vandemeulebroucke, J., 13 aug 2023, In: Cancers. 15, 16, 4083.Onderzoeksoutput: Article › peer review
Open AccessBestand6 Downloads (Pure) -
Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine
Ertveldt, T., Meulewaeter, S., De Vlaeminck, Y., Olarte, O., Broos, K., Van Calenbergh, S., Bourgeois, S., Deprez, J., Heremans, Y., Goyvaerts, C., Staels, W., De Smedt, S., Dewitte, H., Devoogdt, N., Keyaerts, M., Verbeke, R., Barbé, K., Lentacker, I. & Breckpot, K., 9 okt 2023, In: Theranostics. 13, 15, blz. 5483-5500 18 blz.Onderzoeksoutput: Article › peer review
Open AccessBestand13 Downloads (Pure) -
Phase I Study of [68Ga]Ga-Anti-CD206-sdAb for PET/CT Assessment of Protumorigenic Macrophage Presence in Solid Tumors (MMR Phase I)
Gondry, O., Xavier, C., Raes, L., Heemskerk, J., Devoogdt, N., Everaert, H., Breckpot, K., Lecocq, Q., Decoster, L., Fontaine, C., Schallier, D., Aspeslagh, S., Vaneycken, I., Raes, G., Van Ginderachter, J. A., Lahoutte, T., Caveliers, V. & Keyaerts, M., sep 2023, In: Journal of Nuclear Medicine. 64, 9, blz. 1378-1384 7 blz.Onderzoeksoutput: Article › peer review
Open AccessBestand2 Citaten (Scopus)1 Downloads (Pure)
Prijzen
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Alavi-Mandell Award from Journal of Nuclear Medicine
Krasniqi, Ahmet (Recipient), D'Huyvetter, Matthias (Recipient), Devoogdt, Nick (Recipient) & Keyaerts, Marleen (Recipient), 16 apr 2019
Prijs: Prize (including medals and awards)
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Best Poster Award
Awada, Gil (Recipient), Özdemir, Ibrahim (Recipient), Schwarze, Julia Katharina (Recipient), Daeninck, Emma (Recipient), Gondry, Odrade (Recipient), Jansen, Y. (Recipient), Seremet, T. (Recipient), Keyaerts, Marleen (Recipient), Everaert, Hendrik (Recipient) & Neyns, Bart (Recipient), 15 dec 2018
Prijs: Prize (including medals and awards)
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Certificat of Young Speaker Award
Lecocq, Quentin (Recipient), Broos, K. (Recipient), Bridoux, Jessica (Recipient), Raes, Geert (Recipient), Xavier, Catarina (Recipient), Devoogdt, Nick (Recipient), Keyaerts, Marleen (Recipient) & Breckpot, Karine (Recipient), 1 feb 2019
Prijs: Prize (including medals and awards)
Bestand -
ESMI presentation award for best oral presentation
Bridoux, Jessica (Recipient), Broos, K. (Recipient), Lecocq, Quentin (Recipient), Crauwels, M. (Recipient), Martin, Charlotte (Recipient), Cleeren, F. (Recipient), Kondrashov, M. (Recipient), Ballet, Steven (Recipient), Bormans, G. (Recipient), Schou, M. (Recipient), Elmore, C. (Recipient), Raes, Geert (Recipient), Breckpot, Karine (Recipient), Muyldermans, Serge (Recipient), Devoogdt, Nick (Recipient), Keyaerts, Marleen (Recipient), Caveliers, Vicky (Recipient) & Xavier, Catarina (Recipient), 17 jan 2020
Prijs: Prize (including medals and awards)
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Knowledge for Growth 2018 Ghent - poster award
Broos, K. (Recipient), Lecocq, Quentin (Recipient), Bridoux, Jessica (Recipient), Raes, Geert (Recipient), Xavier, Catarina (Recipient), Keyaerts, Marleen (Recipient), Devoogdt, Nick (Recipient) & Breckpot, Karine (Recipient), 18 mei 2018
Prijs: Prize (including medals and awards)
Activiteiten
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The development of radiolabeled nanobodies against the next-generation immune checkpoint TIGIT for non-invasive immune phenotyping of tumors
Katty Zeven (Speaker), Timo De Groof (Contributor), Robin Maximilian Awad (Contributor), Wout De Mey (Contributor), Thomas Ertveldt (Contributor), Hannelore Ceuppens (Contributor), Kevin De Jonghe (Contributor), Geert Raes (Contributor), Marleen Keyaerts (Contributor), Karine Breckpot (Contributor) & Nick Devoogdt (Contributor)
16 mrt 2023Activiteit: Talk or presentation at a conference
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Using the site-specific radiolabeling of a PD-L1 nanobody via maleimide–cysteine chemistry to develop a PET-tracer as screening tool for personalized oncology treatment
Dora Mugoli Chigoho (Speaker), Jessica Bridoux (Speaker), Catarina Xavier (Speaker), Vicky Caveliers (Speaker), Marleen Keyaerts (Speaker), Nick Devoogdt (Speaker), Karine Breckpot (Speaker), Robin Maximilian Awad (Speaker) & Quentin Lecocq (Speaker)
7 mei 2022Activiteit: Talk or presentation at a conference
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The diagnostic utility of 18F-FDG PET/CT in intensive care patients: a retrospective study
Lynn De Mey (Speaker), Jeroen De Filette (Contributor), Duc Nam Nguyen (Contributor), Sophie Bourgeois (Contributor), Amelientje Bracke (Contributor), Marleen Keyaerts (Contributor), Lode Goethals (Contributor), Tony Lahoutte (Contributor) & Hendrik Everaert (Contributor)
7 sep 2022 → 11 sep 2022Activiteit: Talk or presentation at a conference
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Preclinical validation of [18F]-FB-(Anti Human PD-L1) Nanobody for PET imaging
Herlinde Dierick (Speaker), Karine Breckpot (Contributor), Nick Devoogdt (Contributor), Marleen Keyaerts (Contributor), Vicky Caveliers (Contributor), Tony Lahoutte (Contributor) & Jessica Bridoux (Contributor)
7 mei 2022Activiteit: Talk or presentation at a conference
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Nanobody-mediated molecular imaging provides spatiotemporal insight in mRNA-vaccine-induced PD-L1 upregulation
Thomas Ertveldt (Speaker), Sofie Meulewaeter (Speaker), Ine Lentacker (Contributor), Rein Verbeke (Contributor), Stefaan De Smedt (Contributor), Oscar Javier Olarte Rodriguez (Contributor), Kurt Barbé (Contributor), Nick Devoogdt (Contributor), Marleen Keyaerts (Contributor), Heleen Dewitte (Contributor) & Karine Breckpot (Contributor)
19 apr 2021Activiteit: Talk or presentation at a workshop/seminar
Knipsels
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Nanobodies in de strijd tegen kanker
Tony Lahoutte & Marleen Keyaerts
1/09/17
1 Mediabijdrage
Pers / media: !!Research
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VUB-onderzoek naar immuumtherapie voor melanoom ondersteund door Melanoma Research Alliance
Karine Breckpot & Marleen Keyaerts
30/06/17
1 item van Media-aandacht
Pers / media: !!Research
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Team K - De helden in de strijd tegen kanker
Marleen Keyaerts & Kris Thielemans
26/12/15
1 item van Media-aandacht
Pers / media: !!Research
Scriptie
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123I-2-Iodo-Tyrosine, a new tumour imaging agent: biodistribution, dosimetry and initial clinical evaluation in brain tumours
Auteur: Keyaerts, M., Bossuyt, A. & Lahoutte, T., 7 jul 2005Begeleider: Bossuyt, A. (Promotor) & Lahoutte, T. (Advisor)
Scriptie/Masterproef: Master's Thesis
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Development of a circulating tumor cell model in mice
Auteur: Vandereycken, J., Lahoutte, T., Goethals, L. & Keyaerts, M., 10 jun 2015Scriptie/Masterproef: Master's Thesis
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Effectiveness of the implementation of insertion and maintenance bundles in prevention of central line associated bloodstream infections (CLABSI) in patients admitted in a neonatal intensive care unit
Auteur: Leeman, M., Cools, F. & Keyaerts, M., 22 jun 2018Scriptie/Masterproef: Master's Thesis
Bestand -
FDG PET/CT parameters voor de voorspelling van algemene en progressievrije overleving na pembrolizumab-behandeling bij melanoompatienten
Auteur: Özdemir, I., Keyaerts, M., Neyns, B. & Everaert, H., 20 jun 2018Scriptie/Masterproef: Master's Thesis
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Fractional flow reserve and coronary computed tomography angiography in the noninvasive assessment of coronary artery disease
Auteur: Delariviere, E. & Keyaerts, M., jun 2018Scriptie/Masterproef: Master's Thesis