Projecten per jaar
Persoonlijk profiel
Expertise
Marleen Keyaerts obtained her PhD in preclinical research about molecular imaging and therapy at the ICMI lab of the VUB. She obtained a senior clinical investigator scholarship of the Research Foundation Flanders in 2013. Marleen now combines her clinical work as a nuclear medicine physician with basic and translational research at the ICMI lab. One of her major goals is the clinical translation of new radiopharmaceuticals for imaging and therapy. She also focuses on cancer immunotherapy, with a special interest in immune checkpoint blockade therapy and targeted radionuclide therapy.
Vingerafdruk
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
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OZR4288: Financiering MZW OZR: Snelle analyse en productie van eiwitten voor klinische translatie met behulp van Biacore en bioreactor systemen.
Devoogdt, N. (Administrative Promotor), Hernot, S. (CoI (Co-Promotor)), De Groof, T. (CoI (Co-Promotor)), Ballet, S. (CoI (Co-Promotor)), Stijlemans, B. (CoI (Co-Promotor)), Massie, A. (CoI (Co-Promotor)), Rooman, I. (CoI (Co-Promotor)), Keyaerts, M. (CoI (Co-Promotor)), Raes, G. (CoI (Co-Promotor)), De Kock, J. (CoI (Co-Promotor)), Breckpot, K. (CoI (Co-Promotor)), De Veirman, K. (CoI (Co-Promotor)) & Caveliers, V. (CoI (Co-Promotor))
24/04/24 → 24/04/28
Project: Fundamenteel
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HERC59: PET camera voor beeldvorming van kleine proefdieren
Devoogdt, N. (Administrative Promotor), Raes, G. (Co-Promoter), Lahoutte, T. (Co-Promoter), Van Ginderachter, J. (Co-Promoter), Caveliers, V. (Co-Promoter), Keyaerts, M. (Co-Promoter), Hernot, S. (Co-Promoter) & D'Huyvetter, M. (Co-Promoter)
1/05/22 → 30/04/26
Project: Fundamenteel
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IOFACC9B: Integratie van een multimodale aanpak om de huidige uitdagingen in immuuntherapie aan te pakken (INTEGRAAL)
Lahoutte, T. (Administrative Promotor), Devoogdt, N. (Co-Promoter), Keyaerts, M. (Co-Promoter), Van Ginderachter, J. (Co-Promoter), Laoui, D. (Co-Promoter), Raes, G. (Co-Promoter), Breckpot, K. (Co-Promoter) & Goyvaerts, C. (Co-Promoter)
1/10/22 → 31/03/24
Project: Toegepast
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BRGRD44: Joint R&D 2020: IMPACT : Verkwikkende precisie Medicijnen voor voorspellende beeldvorming van sdAb-basis anti-kanker theranostica
Lahoutte, T. (Administrative Promotor), Keyaerts, M. (Administrative Promotor), Krasniqi, A. (CoI (Co-Promotor)), Breckpot, K. (Administrative Promotor) & Goyvaerts, C. (CoI (Co-Promotor))
1/07/20 → 30/06/24
Project: Toegepast
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IOF3009: GEAR: Integratie van een multimodale aanpak om de huidige uitdagingen in immuuntherapie aan te pakken (INTEGRAAL)
Lahoutte, T. (Administrative Promotor), Devoogdt, N. (Co-Promoter), Keyaerts, M. (Co-Promoter), Van Ginderachter, J. (Co-Promoter), Laoui, D. (Co-Promoter), Raes, G. (Co-Promoter), Breckpot, K. (Co-Promoter), Goyvaerts, C. (Co-Promoter), Raes, G. (Mandataris), Bridoux, J. (Mandataris) & Baudhuin, H. V. (Mandataris)
1/01/20 → 30/06/25
Project: Toegepast
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Efficient α and β- radionuclide therapy targeting fibroblast activation protein-α in an aggressive preclinical mouse tumour model
Ceuppens, H., Pombo Antunes, A. R., Navarro, L., Ertveldt, T., Berdal, M., Nagachinta, S., De Ridder, K., Lahoutte, T., Keyaerts, M., Devoogdt, N., Goyvaerts, C., D'Huyvetter, M. & Breckpot, K., jan. 2025, In: European Journal of Nuclear Medicine and Molecular Imaging. 52, 2, blz. 444-457 14 blz.Onderzoeksoutput: Article › peer review
Open AccessBestand7 Citaten (Scopus)9 Downloads (Pure) -
Immune modulation following α and β- radionuclide therapy targeting fibroblast activation protein-α in a preclinical tumor model
Ceuppens, H., De Ridder, K., Ertveldt, T., Zeven, K., de Mey, W., Pombo Antunes, A. R., Navarro, L., Dumauthioz, N., Lahoutte, T., Debacker, J., Devoogdt, N., Keyaerts, M., D'Huyvetter, M., Goyvaerts, C. & Breckpot, K., 1 dec. 2025, In: Oncoimmunology. 14, 1, 16 blz., 2540054.Onderzoeksoutput: Article › peer review
Open Access -
[68Ga]Ga-NOTA-anti-HER2-VHH1PET/CT Imaging of brain metastasis: first clinical results in patients with HER2 positive and HER2 negative breast cancer.
De Mey, L., Gondry, O. (Redacteur), Bourgeois, S. (Redacteur), Bracke, A. (Redacteur), Everaert, H. (Redacteur), Goethals, L. (Redacteur), Raes, L. (Redacteur), Caveliers, V. (Redacteur), Van den Block, S. (Redacteur), Decoster, L. (Redacteur), Fontaine, C. (Redacteur), Devoogdt, N. (Redacteur), Dierick, H. (Redacteur), Cousaert, J. (Redacteur), Lahoutte, T. (Redacteur) & Keyaerts, M. (Redacteur), 2024.Onderzoeksoutput: Poster
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An interpretable deep learning approach for lesion detection and segmentation on whole-body [18F]FDG PET/CT
Dirks, I., Keyaerts, M., Neyns, B. & Vandemeulebroucke, J., 2 apr. 2024, Proc. SPIE 12926, Medical Imaging 2024: Image Processing. SPIE, Vol. 12926. 10 blz. 1292617. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 12926).Onderzoeksoutput: Conference paper
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Generic semi-automated radiofluorination strategy for single domain antibodies: [18F]FB-labelled single domain antibodies for PET imaging of fibroblast activation protein-α or folate receptor-α overexpression in cancer
Dierick, H., Navarro, L., Ceuppens, H., Ertveldt, T., Pombo Antunes, A. R., Keyaerts, M., Devoogdt, N., Breckpot, K., D'Huyvetter, M., Lahoutte, T., Caveliers, V. & Bridoux, J., dec. 2024, In: EJNMMI Radiopharmacy and Chemistry. 9, 1, 14 blz., 54.Onderzoeksoutput: Article › peer review
Open AccessBestand8 Citaten (Scopus)61 Downloads (Pure)
Datasets
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DataSet-Targeted Radionuclide Therapy with Low and High-Dose Lutetium-177-Labeled Single Domain Antibodies Induces Distinct Immune Signatures in a Mouse Melanoma Model
Ertveldt, T. (Creator), De Beck, L. (Creator), De Ridder, K. (Creator), Locy, H. (Creator), de Mey, W. (Creator), Goyvaerts, C. (Creator), Lecocq, Q. (Creator), Ceuppens, H. (Creator), De Vlaeminck, Y. (Creator), Awad, R. M. (Creator), Keyaerts, M. (Creator), Devoogdt, N. (Creator), D'Huyvetter, M. (Creator), Breckpot, K. (Creator) & Krasniqi, A. (Creator), Zenodo, 16 dec. 2024
Dataset
Prijzen
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Alavi-Mandell Award from Journal of Nuclear Medicine
Krasniqi, A. (Recipient), D'Huyvetter, M. (Recipient), Devoogdt, N. (Recipient) & Keyaerts, M. (Recipient), 16 apr. 2019
Prijs: Prize (including medals and awards)
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Best Poster Award
Awada, G. (Recipient), Özdemir, I. (Recipient), Schwarze, J. K. (Recipient), Daeninck, E. (Recipient), Gondry, O. (Recipient), Jansen, Y. (Recipient), Seremet, T. (Recipient), Keyaerts, M. (Recipient), Everaert, H. (Recipient) & Neyns, B. (Recipient), 15 dec. 2018
Prijs: Prize (including medals and awards)
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Certificat of Young Speaker Award
Lecocq, Q. (Recipient), Broos, K. (Recipient), Bridoux, J. (Recipient), Raes, G. (Recipient), Xavier, C. (Recipient), Devoogdt, N. (Recipient), Keyaerts, M. (Recipient) & Breckpot, K. (Recipient), 1 feb. 2019
Prijs: Prize (including medals and awards)
Bestand -
ESMI presentation award for best oral presentation
Bridoux, J. (Recipient), Broos, K. (Recipient), Lecocq, Q. (Recipient), Crauwels, M. (Recipient), Martin, C. (Recipient), Cleeren, F. (Recipient), Kondrashov, M. (Recipient), Ballet, S. (Recipient), Bormans, G. (Recipient), Schou, M. (Recipient), Elmore, C. (Recipient), Raes, G. (Recipient), Breckpot, K. (Recipient), Muyldermans, S. (Recipient), Devoogdt, N. (Recipient), Keyaerts, M. (Recipient), Caveliers, V. (Recipient) & Xavier, C. (Recipient), 17 jan. 2020
Prijs: Prize (including medals and awards)
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Knowledge for Growth 2018 Ghent - poster award
Broos, K. (Recipient), Lecocq, Q. (Recipient), Bridoux, J. (Recipient), Raes, G. (Recipient), Xavier, C. (Recipient), Keyaerts, M. (Recipient), Devoogdt, N. (Recipient) & Breckpot, K. (Recipient), 18 mei 2018
Prijs: Prize (including medals and awards)
Activiteiten
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Nanobody-based tracers in image-guided surgery applications
Keyaerts, M. (Speaker), Debacker, J. (Speaker) & Hernot, S. (Contributor)
17 mei 2025Activiteit: Talk or presentation at a conference
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Efficient α and β- radionuclide therapy targeting fibroblast activation protein-α in an aggressive preclinical mouse tumour model.
Ceuppens, H. (Speaker), Pombo Antunes, A. R. (Contributor), Navarro, L. (Contributor), Ertveldt, T. (Contributor), Berdal, M. (Contributor), Nagachinta, S. (Contributor), De Ridder, K. (Contributor), Keyaerts, M. (Contributor), Devoogdt, N. (Contributor), Goyvaerts, C. (Contributor), D'Huyvetter, M. (Contributor) & Breckpot, K. (Contributor)
23 okt. 2024Activiteit: Talk or presentation at a conference
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PET/CT imaging with [68Ga]Ga-NOTA-anti-HER2-VHH1 in cancer patients with potential HER2 expression: first clinical results.
De Mey, L. (Speaker), Gondry, O. (Contributor), Bourgeois, S. (Contributor), Bracke, A. (Contributor), Everaert, H. (Contributor), Goethals, L. (Contributor), Raes, L. (Contributor), Caveliers, V. (Contributor), Van den Block, S. (Contributor), Joris, S. (Contributor), de Haar-Holleman, A. (Contributor), Fontaine, C. (Contributor), Devoogdt, N. (Contributor), Dierick, H. (Contributor), Cousaert, J. (Contributor), Lahoutte, T. (Contributor) & Keyaerts, M. (Contributor)
22 okt. 2024Activiteit: Talk or presentation at a conference
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PET/CT imaging of high mannose receptor expressing macrophages: first clinical results in cancer and inflammatory disease
De Mey, L. (Speaker), Gondry, O. (Contributor), Bracke, A. (Contributor), Bourgeois, S. (Contributor), Everaert, H. (Contributor), Goethals, L. (Contributor), Raes, L. (Contributor), Gebruers, J. (Contributor), Waelput, W. (Contributor), Caveliers, V. (Contributor), Debacker, J. (Contributor), Devoogdt, N. (Contributor), Dierick, H. (Contributor), Cousaert, J. (Contributor), De Beule, N. (Contributor), Kerselaers, L. A. A. (Contributor), Keyaerts, M. (Contributor) & Lahoutte, T. (Contributor)
12 mrt. 2024Activiteit: Talk or presentation at a conference
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PET/CT imaging with [68Ga]Ga-NOTA-anti-MMR-VHH2 in patients with NSCLC: Interim results of the MAGMA trial
De Mey, L. (Speaker), Bourgeois, S. (Contributor), Bracke, A. (Contributor), Everaert, H. (Contributor), Goethals, L. (Contributor), Gondry, O. (Contributor), Debacker, J. (Contributor), Keyaerts, M. (Contributor), Devoogdt, N. (Contributor), Forsyth, R. (Contributor), Locy, H. (Contributor), Raes, L. (Contributor), Caveliers, V. (Contributor), Van den Block, S. (Contributor), Vaneycken, I. (Contributor), Cousaert, J. (Contributor) & Lahoutte, T. (Contributor)
11 okt. 2024Activiteit: Talk or presentation at a conference
Knipsels
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VUB-onderzoek naar immuumtherapie voor melanoom ondersteund door Melanoma Research Alliance
30/06/17
1 item van Media-aandacht
Pers / media: !!Research
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Team K - De helden in de strijd tegen kanker
26/12/15
1 item van Media-aandacht
Pers / media: !!Research
Scriptie
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123I-2-Iodo-Tyrosine, a new tumour imaging agent: biodistribution, dosimetry and initial clinical evaluation in brain tumours
Keyaerts, M. ((PhD) Student), Bossuyt, A. (Promotor) & Lahoutte, T. (Advisor), Bossuyt, A. (Promotor) & Lahoutte, T. (Advisor), 7 jul. 2005Scriptie/Masterproef: Master's Thesis
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Development of a circulating tumor cell model in mice
Vandereycken, J. ((PhD) Student), Lahoutte, T. (Promotor), Goethals, L. (Co-promotor) & Keyaerts, M. (Jury), 10 jun. 2015Scriptie/Masterproef: Master's Thesis
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Effectiveness of the implementation of insertion and maintenance bundles in prevention of central line associated bloodstream infections (CLABSI) in patients admitted in a neonatal intensive care unit
Leeman, M. ((PhD) Student), Cools, F. (Promotor) & Keyaerts, M. (Jury), 22 jun. 2018Scriptie/Masterproef: Master's Thesis
Bestand -
FDG PET/CT parameters voor de voorspelling van algemene en progressievrije overleving na pembrolizumab-behandeling bij melanoompatienten
Özdemir, I. ((PhD) Student), Keyaerts, M. (Promotor), Neyns, B. (Promotor) & Everaert, H. (Promotor), 20 jun. 2018Scriptie/Masterproef: Master's Thesis
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Fractional flow reserve and coronary computed tomography angiography in the noninvasive assessment of coronary artery disease
Delariviere, E. ((PhD) Student) & Keyaerts, M. (Jury), jun. 2018Scriptie/Masterproef: Master's Thesis