Onderzoeksoutput

Onderzoeksoutput per jaar 1970 2012 2013 2014 2015 2016 2017 2019 2020 2021 2022 2023 2024 2025

• 10227 Citaties
• 48 h-index
• 257 Article
• 69 Poster
• 33 Chapter
• 9 Meeting abstract (Book)
• 35 Meer
  • 8 Special issue
  • 7 Meeting abstract (Journal)
  • 4 Conference paper
  • 3 Book
  • 3 Editorial
  • 3 Scientific review
  • 3 Other contribution
  • 2 Patent
  • 1 Other scientific journal contribution
  • 1 PhD Thesis

Onderzoeksoutput per jaar

Onderzoeksoutput per jaar

Zoekresultaten

• 2024

  Assessment of connexin43 hemichannel functionality based on cytosolic uptake of Yo-Pro1

  Van Campenhout, R., Sanz-Serrano, J., Cooreman, A., De Vlaeminck, Y., Breckpot, K., Kadam, P., Tabernilla Garcia, A. & Vinken, M., 2024, Assessment of connexin43 hemichannel functionality based on cytosolic uptake of Yo-Pro1. Mammano, F. & Retamal, M. (redactie). Methods in Molecular Biology, Vol. 2801. blz. 75-85

  Onderzoeksoutput: Chapter

• Effects of altered gravity on the liver

  Cools, B. & Vinken, M., 8 jan 2024, (Accepted/In press) Fundamentals of Space Medicine and Clinical Technology. Elsevier, 12 blz.

  Onderzoeksoutput: Chapter › peer review

  • gravity 100%
  • liver 54%
  • microgravity 43%
  • space flight 29%
  • carbohydrate metabolism 24%

• Hepatology during spaceflight

  Cools, B., Helvacıoğlu Akyüz, S. & Vinken, M., 6 dec 2024, Precision Medicine in Space.

  Onderzoeksoutput: Chapter › peer review

• Precision Medicine for Long and Safe Permanence of Humans in Space: Hepatology during spaceflight

  Cools, B., Helvacıoğlu Akyüz, S. & Vinken, M., 30 nov 2024, Academic Press. Krittanawong, C. (redactie). 1 redactie Elsevier, blz. 593-600

  Onderzoeksoutput: Chapter

• The integration of adverse outcome pathways and aggregate exposure pathways for food safety testing purposes: pesticides as a case study: The integration of adverse outcome pathways and aggregate exposure pathways for food safety testing purposes: pesticides as a case study

  Avirvarei, A-C., Callewaert, E., Xiftou, K., Vinken, M. & Sanz-Serrano, J., 9 dec 2024, (Accepted/In press) Chemical contaminants in foods: understanding and managing risks. 59 blz.

  Onderzoeksoutput: Chapter › peer review
• 2021

  Connexin hemichannels

  Vinken, M., 1 mei 2021, Encyclopedia of Molecular Pharmacology 3rd edition. 3 redactie Springer New York, blz. 478-483 6 blz.

  Onderzoeksoutput: Chapter › peer review
• 2020

  Adverse outcome pathways as versatile tools in liver toxicity testing

  Gustafson, E., Gijbels, E., dos Santos Rodrigues, B., Vilas-Boas, V. & Vinken, M., 2020, (Accepted/In press) Methods in Molecular Biology volume xxx: In Silico Methods for Predicting Drug Toxicity. Benfenati, E. (redactie). Springer Protocols

  Onderzoeksoutput: Chapter
• 2019

  Alcohol intake and cancer risk, in: Nutrition and Cancer Prevention.

  Vinken, M., 2019, Molecular Mechanisms to Dietary Recommendations. Ong, T. P. & Moreno, F. S. (redactie). Royal Society of Chemistry, blz. 108-127 19 blz.

  Onderzoeksoutput: Chapter › peer review
• 2016

  Adverse outcome pathways as tools to assess drug-induced toxicity

  Vinken, M., 30 mei 2016, Methods in Molecular Biology: In Silico Methods for Predicting Drug Toxicity. New York: Springer New York, Vol. 1425. blz. 325-337 (Methods in Molecular Biology; vol. 1425).

  Onderzoeksoutput: Chapter

  16 Citaten (Scopus)

• Analysis of Liver Connexin Expression Using Reverse Transcription Quantitative Real-Time Polymerase Chain Reaction

  Maes, M., Willebrords, J., Crespo Yanguas, S., Cogliati, B. & Vinken, M., 22 mei 2016, Gap Junction Protocols. Vinken, M. & Johnstone, S. (redactie). New York: Springer Protocols, blz. 1-19

  Onderzoeksoutput: Chapter › peer review

  • Chain Reaction 100%
  • Complementary DNA 52%
  • Protein 20%
  7 Citaten (Scopus)

• Detection of connexins in liver cells using sodiumdodecylsulfate polyacrylamide gel electrophoresis and immunoblot analysis

  Willebrords, J., Maes, M., Crespo Yanguas, S., Cogliati, B. & Vinken, M., 22 mei 2016, Gap Junction Protocols. Vinken, M. & Johnstone, S. (redactie). New York: Springer Protocols, blz. 37-53

  Onderzoeksoutput: Chapter › peer review

  • connexins 100%
  • hepatocytes 61%
  • polyacrylamide gel electrophoresis 56%
  • proteins 23%
  • chemiluminescence 16%

• Immunohisto- and cytochemistry analysis of connexins

  Cogliati, B., Maes, M., Alves Pereira, I. V., Willebrords, J., da Silva, T. C., Crespo Yanguas, S. & Vinken, M., 22 mei 2016, Gap Junction Protocols. Vinken, M. & Johnstone, S. (redactie). New York: Springer Protocols, blz. 55-70

  Onderzoeksoutput: Chapter › peer review

  • connexins 100%
  • cytochemistry 88%
  • immunohistochemistry 70%
  • protein synthesis 26%
  • proteins 17%
  4 Citaten (Scopus)
• 2015

  Challenging the predictive power and robustness of an adverse outcome pathway construct from bile salt export pump inhibition to cholestatic liver injury

  Vinken, M., Marcelino Rodrigues, R. & Rogiers, V., 2015, Towards the replacement of in vivo repeated dose systemic toxicity . COACH (redactie). France: Mouzet Imprimerie, Vol. 5. blz. 75-76 2 blz.

  Onderzoeksoutput: Chapter › peer review

• DETECTIVE: detection of endpoints and biomarkers for repeated dose toxicity testing using in vitro systems.

  Wink, S., Van De Water, B., Reif, R., Seddik, H., Stöber, R., Agata, W., Hengstler, J. G., Limonciel, A., Jennings, P., Escher, S., Keun, H., Kleinjans, J. C. S., Kopp Schneider, A., Peterson, H., Ringwald, A., Rogiers, V., Sachinidis, A., Albert, S., Vinken, M., Spitkovsky, D. & 1 anderen, Hescheler, J., 2015, Towards the replacement of in vivo repeated dose systemic toxicity testing. COACH. (redactie). France: Mouzet Imprimerie, Vol. 5. blz. 136-165 29 blz.

  Onderzoeksoutput: Chapter › peer review

• Establishment and Characterization of an In Vitro Model of Fas-Mediated Hepatocyte Cell Death

  Vinken, M., Maes, M., Crespo Yanguas, S., Willebrords, J., Vanhaecke, T. & Rogiers, V., 1 jan 2015, Protocol in in vitro hepatocyte research. Vinken, M. & Rogiers, V. (redactie). New York: Springer New York, Vol. 1250. blz. 95-103 8 blz. (Methods in Molecular Biology; vol. 1250).

  Onderzoeksoutput: Chapter › peer review

  1 Citaat (Scopus)

• HeMiBio: hepatic microfluidic bioreactor

  Barbe, L., Collas, P., Dascher-Nadel, C., Generelli, S., van Grunsven, L., Leite, S., Nahmias, Y., Sancho-Bru, P., Verfaillie, C. & Vinken, M., 1 nov 2015, Towards the replacement of in vivo repeated dose systemic toxicity testing. Vol. 5. blz. 114-134

  Onderzoeksoutput: Chapter

• Immortalized human hepatic cell lines for in vitro testing and research purposes.

  Ramboer, E., Vanhaecke, T., Rogiers, V. & Vinken, M., 2015, Protocols in In Vitro Hepatocyte Research. Vinken, M. & Rogiers, V. (redactie). New York: Humana Press, 24 blz. (Methods in Molecular Biology; vol. 1250).

  Onderzoeksoutput: Chapter › peer review

  • Hepatocytes 100%
  • Cell Line 70%
  • In Vitro Techniques 52%
  • human TERT protein 27%
  • Oncogenes 18%
  44 Citaten (Scopus)

• Measurement of apoptotic and necrotic cell death in primary hepatocyte cultures

  Maes, M., Vanhaecke, T., Cogliati, B., Crespo Yanguas, S., Willebrords, J., Rogiers, V. & Vinken, M., 2015, Protocol in in vitro hepatocyte research. Vinken, M. & Rogiers, V. (redactie). New York: Springer New York, Vol. 1250. blz. 349-361 12 blz. (Methods in Molecular Biology; vol. 1250).

  Onderzoeksoutput: Chapter › peer review

  • cell death 100%
  • hepatocytes 95%
  • apoptosis 65%
  • caspase-3 43%
  • hepatotoxicity 43%

• Mode-of-action working group: capturing mode-of-action knowledge

  Landesmann, B. & Vinken, M., 1 nov 2015, Towards the replacement of in vivo repeated dose systemic toxicity testing. Paris: Mouzet Imprimerie, Vol. 5. blz. 296-299

  Onderzoeksoutput: Chapter
• 2014

  Challenging the predictive power and robustness of an adverse outcome pathway construct from bile salt export pump inhibition to cholestatic liver injury

  Vinken, M. & Rogiers, V., 25 aug 2014, Towards the replacement of in vivo repeated dose systemic toxicity testing. France: Mouzet Imprimerie, Vol. 4. blz. 93-96 4 blz.

  Onderzoeksoutput: Chapter › peer review

• DETECTIVE: detection of endpoints and biomarkers for repeated dose toxicity testing using in vitro systems. Towards the replacement of in vivo repeated dose systemic toxicity testing.

  Marcelino Rodrigues, R., Bremer-Hoffmann, S., De Kock, J., Escher, S., Hengstler, J., Jennings, P., Keun, H., Kleinjans, J., Raivo, K., Kopp Schneider, A., Annette, R., Rogiers, V., Sachinidis, A., Albert, S., Spitkovsky, D., Vanhaecke, T., Vinken, M., Van De Water, B. & Hescheler, J., 2014, Towards the Replacement of in vivo Repeated Dose Systemic Toxicity Testing. Mouzet Imprimerie, Vol. 4. blz. 166-185 20 blz.

  Onderzoeksoutput: Chapter

  • Biomarkers 100%
  • In Vitro Techniques 67%
  • Safety 44%

• DETECTIVE: detection of endpoints and biomarkers for repeated dose toxicity using in vitro systems

  Hescheler, J., Sachinidis, A., Hengstler, J., Van De Water, B., Vinken, M., Jennings, P., Kopp Schneider, A. & Nagarajan, P., 1 feb 2014, Towards the replacement of in vivo repeated dose systemic toxicity testing. Mouzet Imprimerie, Vol. 3. blz. 166-185 24 blz.

  Onderzoeksoutput: Chapter › peer review

• Focus on hepatotoxic modes-of-action in SEURAT-1: rationale and strategy

  Vinken, M., Landesmann, B. & Rogiers, V., 25 aug 2014, Towards the replacement of in vivo repeated dose systemic toxicity testing. France: Mouzet Imprimerie, Vol. 4. blz. 114-125 12 blz.

  Onderzoeksoutput: Chapter › peer review

  • Adverse Outcome Pathways 100%
  • Toxicology 38%
  • Pharmacologic Actions 28%
  • Ocular Vision 16%
  • Decision Making 16%

• HeMiBio: hepatic microfluidic bioreactor

  Bavli, D., Dascher-Nadel, C., van Grunsven, L. A., Jaeger, M., Batista Leite, S., Nahmias, Y., Ordovas, L., Prill, S., Sancho-Bru, P., Verfaillie, C. & Vinken, M., 25 aug 2014, Towards the replacement of in vivo repeated dose systemic toxicity testing. France: Mouzet Imprimerie, Vol. 4. 15 blz.

  Onderzoeksoutput: Chapter › peer review

• Investigation of the fibrotic response induced by methotrexate and acetaminophen in the HeMiBio bioreactor

  van Grunsven, L. A., Vinken, M., Sancho-Bru, P., Nahmias, Y. & Verfaillie, C., 25 aug 2014, Towards the replacement of in vivo repeated dose systemic toxicity testing. France: Mouzet Imprimerie, Vol. 4. blz. 96-98 2 blz.

  Onderzoeksoutput: Chapter › peer review

• Measurement of Cytochrome P450 Enzyme Induction and Inhibition in Human Hepatoma Cells

  Marcelino Rodrigues, R., De Kock, J., Doktorova Tatyana, Y., Rogiers, V., Vanhaecke, T., Rogiers, V. (redactie) & Vinken, M. (redactie), 2014, Protocols in In Vitro Hepatocyte Research. Vinken, M. & Rogiers, V. (redactie). New York: Humana Press, blz. 279-286 7 blz. (Methods in Molecular Biology; vol. 1250).

  Onderzoeksoutput: Chapter › peer review

  • Cytochrome P450 100%
  • Detoxification 20%
  • Chemical Compound 20%
  • Drug 19%
  • Cytochrome 16%
  3 Citaten (Scopus)

• Mode-of-action working group: capturing mode-of-action knowledge

  Landesmann, B. & Vinken, M., 25 aug 2014, Towards the replacement of in vivo repeated dose systemic toxicity testing. France: Mouzet Imprimerie, Vol. 4. blz. 318-320 3 blz.

  Onderzoeksoutput: Chapter › peer review
• 2012

  The interplay between epigenetics and gap junctional intercellular communication

  Vinken, M., Rogiers, V. & Vanhaecke, T., 2012, Cellular Response to the Genotoxic Insult. Greim, H. & Albertini, R. J. (redactie). The Royal Society, blz. 293-311 19 blz.

  Onderzoeksoutput: Chapter › peer review
• 2010

  Epigenetically stabilized primary hepatocyte cultures: a potential sensitive screening tool for non-genotoxic carcinogenicity

  Doktorova Tatyana, Y., Vanhaecke, T., Rogiers, V. & Vinken, M., 2 jul 2010, Alternative Technologies to Animal Testing. Maguire, T. & Novik, E. (redactie). Artech House, blz. 133-145 12 blz. (Methods in Bioengineering).

  Onderzoeksoutput: Chapter › peer review

  • carcinogenicity 100%
  • hepatocytes 72%
  • screening 57%
  • histone deacetylase 27%
  • liver 23%
• 2006

  Hepatocytes in suspension

  Elaut, G., Henkens, T., Rogiers, V., Papeleu, P., Snykers, S., Vanhaecke, T., Vinken, M., Phillips, I. (redactie) & Shephard, E. A. (redactie), 1 mei 2006, Cytochrome P450 Protocols. In: Cytochrome P450 Protocls. Series in: Methods in Molecular Biology. Vol. 320, Chap. 29, pp. 255-263, 2006, Vol. 320. blz. 255-263 8 blz. (Methods in Molecular Biology).

  Onderzoeksoutput: Chapter › peer review

  • hepatocytes 100%
  • biotransformation 65%
  • xenobiotics 47%
  • thawing 45%
  • cryopreservation 44%

• Isolation of rat hepatocytes

  Elaut, G., Henkens, T., Rogiers, V., Papeleu, P., Snykers, S., Vanhaecke, T., Vinken, M., Phillips, I. (redactie) & Shephard, E. A. (redactie), 1 mei 2006, Cytochrome P450 Protocols. In: Cytochrome P450 Protocols. Series in: Methods in Molecular Biology. Vol. 320, Chap. 26, pp. 229-246, 2006, Vol. 320. blz. 229-246 17 blz.

  Onderzoeksoutput: Chapter › peer review

  • hepatocytes 100%
  • rats 58%
  • histone deacetylase 30%
  • drug development 28%
  • liver 26%
  87 Citaten (Scopus)

• Rat hepatocyte cultures: conventional monolayer cultures and cocultures with rat liver epithelial cells

  Henkens, T., Vanhaecke, T., Papeleu, P., Elaut, G., Vinken, M., Snykers, S., Rogiers, V., Phillips, I. (redactie) & Shephard, E. A. (redactie), 1 mei 2006, Cytochrome P450 Protocols. Methods in Molecular Biology: Cytochrome P450 Protocols: Second Edition, I.R. Philips and E.A. Shepard (eds), Humana Press Inc., Totowa, NJ, USA, Vol 320, Chapter 27, pp. 239-246, 2006, Vol. 320. blz. 239-246 17 blz.

  Onderzoeksoutput: Chapter › peer review

  • coculture 100%
  • hepatocytes 81%
  • epithelial cells 79%
  • rats 47%
  • xenobiotics 13%

• Rat hepatocytes cultures: collagen gel sandwich and immobilization cultures

  Vinken, M., Elaut, G., Henkens, T., Papeleu, P., Snykers, S., Vanhaecke, T. & Rogiers, V., 1 mei 2006, Cytochrome P450 Protocols. In: Cytochrome P450 Protocols. Series in: Methods in Molecualr Biology. Vol. 320, Chap. 28, pp. 247-254, 2006, Vol. 320. blz. 247-254 8 blz. (Methods in Molecular Biology).

  Onderzoeksoutput: Chapter › peer review

  • sandwiches 100%
  • hepatocytes 77%
  • collagen 75%
  • gels 58%
  • rats 45%
  9 Citaten (Scopus)