Projecten per jaar
Vingerafdruk
Verdiep u in de onderzoeksgebieden waarop Nico De Leu actief is. Deze onderwerplabels komen uit het werk van deze persoon. Samen vormen ze een unieke vingerafdruk.
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
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FWOTM1255: MACBETh: Ontrafelen van de rol van MACrofagen in BETa cel (re)generatie.
Willems, L. (Mandataris), De Leu, N. (Administrative Promotor), Staels, W. (CoI (Co-Promotor)) & Van Ginderachter, J. (CoI (Co-Promotor))
1/11/24 → 31/10/28
Project: Fundamenteel
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HERC66: 3D-CELLMAP: Onthullen van complexe celinteracties in weefsels door middel van 3D super-resolutie proteïne multiplex beeldvorming.
Movahedi, K. (Administrative Promotor), Rooman, I. (CoI (Co-Promotor)), Sermon, K. (CoI (Co-Promotor)), De Bundel, D. (CoI (Co-Promotor)), Fioravanti, A. (CoI (Co-Promotor)), Staels, W. (CoI (Co-Promotor)), Magez, S. (CoI (Co-Promotor)), Breckpot, K. (CoI (Co-Promotor)), De Kock, J. (CoI (Co-Promotor)), Laoui, D. (CoI (Co-Promotor)), Goyvaerts, C. (CoI (Co-Promotor)), Smolders, I. (CoI (Co-Promotor)), Van Ginderachter, J. (CoI (Co-Promotor)), Marcelino Rodrigues, R. (CoI (Co-Promotor)), De Leu, N. (CoI (Co-Promotor)), van Grunsven, L. (CoI (Co-Promotor)), Hernot, S. (CoI (Co-Promotor)), Peeters, E. (CoI (Co-Promotor)), Vanhaecke, T. (CoI (Co-Promotor)), De Veirman, K. (CoI (Co-Promotor)), Ruytinx, J. (CoI (Co-Promotor)), Van Schependom, J. (CoI (Co-Promotor)), Kortekaas, I. (CoI (Co-Promotor)) & Goossens, E. (CoI (Co-Promotor))
1/05/24 → 31/05/28
Project: Fundamenteel
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FWOAL1090: Gebruik van vasculaire signalen om de functionele maturatie van iPSC-afgeleide betacellen te verbeteren.
De Leu, N. (Administrative Promotor)
1/01/23 → 31/12/26
Project: Fundamenteel
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FWOTM1142: Het ontraadselen van de betrokkenheid van ijzermetabolisme in beta cel differentiatie, maturatie en functie
Staels, W. (Administrative Promotor), De Leu, N. (Co-Promoter), Heimberg, H. (Co-Promoter) & Van Mulders, A. (Mandataris)
1/11/22 → 31/10/26
Project: Fundamenteel
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OZR4199: OZR opvangmandaat post doc Willems Lien
Willems, L. (Administrative Promotor) & De Leu, N. (Administrative Promotor)
1/11/23 → 31/10/24
Project: Fundamenteel
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A new postnatal role for Neurogenic3 in ∂-cells
Coenen, S., van den Ameele, J. (Contributor), Kellens, Y. (Contributor), Pierreux, J. (Contributor), Van Mulders, A. (Contributor), Degroote, L. (Contributor), Bourgeois, S. (Contributor), Willems, L. (Contributor), Heremans, Y. (Contributor), De Leu, N. (Contributor) & Staels, W. (Contributor), 22 okt. 2025, (Unpublished).Onderzoeksoutput: Poster
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Combination therapy of low-dose anti-CD3 with GLP1-E2 delays and reduces type 1 diabetes onset in non-obese diabetic mice
Degroote, L., Bourgeois, S. (Contributor), Van Mulders, A. (Contributor), Pierreux, J. (Contributor), Coenen, S. (Contributor), Willems, L. (Contributor), Heremans, Y. (Contributor), Staels, W. (Contributor) & De Leu, N. (Contributor), 22 okt. 2025, (Unpublished).Onderzoeksoutput: Unpublished abstract
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Iron deficiency induces maturation-dependent loss of pancreatic β-cells
Staels, W., Mulders, A. V., Willems, L., Coenen, S., Bourgeois, S., Yi, X., Tong, Y., Ates, G., Massie, A., Pierreux, J., Degroote, L., Sawatani, T., Vinci, C., Leuckx, G., Heremans, Y., Carlotti, F., Koning, E. D., Scharfmann, R., Cnop, M. & Leu, N. D., 4 jun. 2025, 70 blz.Onderzoeksoutput: Other contribution
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Verapamil and low-dose anti-mouse thymocyte globulin combination therapy stably reverses recent-onset type 1 diabetes in NOD mice by acting on the beta cell and immune axes.
Degroote, L., Martens, P.-J., Viaene, M., Heremans, Y., Leuckx, G., Geukens, N., De Leu, N., Staels, W., Mathieu, C. & Gysemans, C., okt. 2025, In: Diabetologia. 68, 10, blz. 2263-2276 14 blz.Onderzoeksoutput: Article › peer review
Open Access2 Citaten (Scopus) -
A critical role for iron import through the transferrin receptor in developing ß-cells
Van Mulders, A., Staels, W., Willems, L., Coenen, S., Bourgeois, S., Ye, X., Tong, Y., Leuckx, G., Heremans, Y., De Koning, E., Carlotti, F., Scharfmann, R., Cnop, M. & De Leu, N., 16 nov. 2024, blz. 486. 487 blz.Onderzoeksoutput: Unpublished abstract
Prijzen
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Belgian Endocrine Society, annual lecture
De Leu, N. (Recipient), 2015
Prijs: National/international honour
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Belgian Endocrine Society Annual Lecture Award
De Leu, N. (Recipient), 2015
Prijs: Prize (including medals and awards)
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McKinsey and Company Scientific Award
De Leu, N. (Recipient), 2015
Prijs: Prize (including medals and awards)
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Novo Nordisk prijs voor Diabetologie
De Leu, N. (Recipient), 2018
Prijs: National/international honour
Activiteiten
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Targeting system xc- to simultaneously tackle the metabolic and neurological comorbidities of diet-induced obesity
Walckiers, J. (Speaker), Dalmas, E. (Contributor), Vanonckelen, O. (Contributor), Mackens, L. (Contributor), Van Mulders, A. (Contributor), Dreessen, T. (Contributor), Staels, W. (Contributor), De Leu, N. (Contributor), Ates, G. (Contributor) & Massie, A. (Contributor)
20 okt. 2025Activiteit: Talk or presentation at a conference
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Biomarkers of beta cell loss, dysglycemia and responsiveness to immune intervention in (a)symptomatic type 1 diabetes (Evenement)
Desouter, A. (Presenter) & De Leu, N. (Jury)
23 sep. 2025Activiteit: Membership of peer-review panel or committee
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Duct cells in development, regeneration, and transplantation:charting a path to new islets (Evenement)
Balak, J. (Presenter) & De Leu, N. (Jury)
16 mei 2025Activiteit: Membership of peer-review panel or committee
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Combination therapy of low-dose anti-CD3 with GLP1-E2 delays and reduces type 1 diabetes in non-obese diabetic mice
Degroote, L. (Speaker), Bourgeois, S. (Contributor), Van Mulders, A. (Contributor), Pierreux, J. (Contributor), Willems, L. (Contributor), Coenen, S. (Contributor), Heremans, Y. (Contributor), Staels, W. (Contributor) & De Leu, N. (Contributor)
22 okt. 2025Activiteit: Talk or presentation at a conference
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Iron deficiency induces maturation-dependent loss of pancreatic β-cells
Van Mulders, A. (Speaker), Willems, L. (Contributor), Coenen, S. (Contributor), Bourgeois, S. (Contributor), Heremans, Y. (Contributor), Degroote, L. (Contributor), Pierreux, J. (Contributor), De Leu, N. (Contributor) & Staels, W. (Contributor)
25 okt. 2025Activiteit: Talk or presentation at a conference
Scriptie
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Can beta cell injury induce homing of an intravenous injected stem cell line, seRM26, to pancreas?
De Leu, N. ((PhD) Student) & Heimberg, H. (Promotor), Heimberg, H. (Promotor), 2005Scriptie/Masterproef: Master's Thesis