Projecten per jaar
Persoonlijk profiel
Expertise
I performed a PhD in Pharmaceutical Sciences at the MITH laboratory of the Vrije Universiteit Brussel (Brussel, Belgium). I worked on the application of single-domain antibody-based tracer compounds in image-guided cancer surgery. Previously, I studied Pharmaceutical Sciences at this university and obtained a Master of Sciences focussing on Drug Development.
Vingerafdruk
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Projecten
- 2 Afgelopen
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FWOSB74: Intra-operatieve beeldvorming aan de hand van fluorescent- gelabelde nanobodies tijdens prostaat- en baarmoederhalskanker operaties.
Hernot, S. (Administrative Promotor), Devoogdt, N. (Co-Promoter) & Declerck, N. (Mandataris)
1/11/19 → 31/10/23
Project: Fundamenteel
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ANI228: Intraoperatieve beeldvorming bij prostaat- en baarmoederhalskankerchirurgie met fluorescent gelabelde nanobodies
Hernot, S. (Administrative Promotor) & Declerck, N. (CoI (Co-Promotor))
1/10/19 → 31/10/19
Project: Fundamenteel
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A Comparative Study on the Effect of Near-Infrared Fluorescent Dyes on the Pharmacokinetic Behavior of Nanobody-Based Tracers for In Vivo Imaging
Declerck, N. B., Declercq, S., Debie, P., Du Ville, J., Mateusiak, Ł., Saliën, J., Stroet, M. C. M., Luciano, M. P., Li, D.-H., Schnermann, M. J., Smith, B. D. & Hernot, S., 13 nov. 2025, In: Journal of medicinal chemistry. 68, 21, blz. 23472-23484 13 blz.Onderzoeksoutput: Article › peer review
6 Citaten (Scopus) -
Generation and Characterization of Novel Pan-Cancer Anti-uPAR Fluorescent Nanobodies as Tools for Image-Guided Surgery
Mateusiak, Ł., Floru, S., De Groof, T. W. M., Wouters, J., Declerck, N. B., Debie, P., Janssen, S., Zeven, K., Breckpot, K., Puttemans, J., Vincke, C., Devoogdt, N. & Hernot, S., aug. 2024, In: Advanced Science. 11, 30, 11 blz., e2400700.Onderzoeksoutput: Article › peer review
Open AccessBestand9 Citaten (Scopus)98 Downloads (Pure) -
A convenient labeling strategy for the preparation of fluorescent/radioactive sdab-based tracers carrying 99mTc and IRDye800CW for intra-operative decision making
Declerck, N., Huygen, C. M., Mateusiak, L., Stroet, M. & Hernot, S., 18 jan. 2023, (Unpublished).Onderzoeksoutput: Unpublished abstract
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Intra-operative imaging in prostate and cervical cancer surgery using fluorescently-labelled nanobodies
Declerck, N., 2023, (Unpublished) Brussels.Onderzoeksoutput: PhD Thesis
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Intraoperative tumor visualization through a specific fluorescently-labeled anti-uPAR targeting single-domain antibody
Vangeloven, E., Mateusiak, L., Floru, S., De Groof, T., Declerck, N., Wouters, J., Janssen, S., Debie, P., Zeven, K., Vincke, C., Puttemans, J., Stroet, M., Ballet, S., Breckpot, K., Devoogdt, N. & Hernot, S., 2023, (Unpublished).Onderzoeksoutput: Poster
Datasets
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Generation and Characterization of Novel Pan-Cancer Anti-uPAR Fluorescent Nanobodies as Tools for Image-Guided Surgery
Mateusiak, L. (Creator), Floru, S. (Researcher), De Groof, T. (Researcher), Wouters, J. (Researcher), Declerck, N. (Researcher), Debie, P. (Researcher), Janssen, S. (Researcher), Zeven, K. (Researcher), Puttemans, J. (Researcher), Vincke, C. (Researcher), Breckpot, K. (Project Member), Devoogdt, N. (Project Member) & Hernot, S. (Supervisor), Zenodo, 26 mrt. 2025
DOI: https://zenodo.org/records/15089920
Dataset
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In vivo optical imaging using a novel fluorescently-labeled single-domain antibody targeting a universal tumor marker
Mateusiak, L. (Speaker), Floru, S. (Contributor), Wouters, J. (Contributor), De Groof, T. (Contributor), Declerck, N. (Contributor), Janssen, S. (Contributor), Debie, P. (Contributor), Zeven, K. (Contributor), Puttemans, J. (Contributor), Breckpot, K. (Contributor), Devoogdt, N. (Contributor) & Hernot, S. (Contributor)
28 jan. 2023Activiteit: Talk or presentation at a conference
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In vivo optical imaging of glioma using a novel uPAR-targeting fluorescent single-domain antibody
Mateusiak, L. (Speaker), Floru, S. (Contributor), De Groof, T. (Contributor), Declerck, N. (Contributor), Wouters, J. (Contributor), Janssen, S. (Contributor), Debie, P. (Contributor), Zeven, K. (Contributor), Vincke, C. (Contributor), Puttemans, J. (Contributor), Stroet, M. (Contributor), Breckpot, K. (Contributor), Devoogdt, N. (Contributor) & Hernot, S. (Contributor)
16 mrt. 2023Activiteit: Talk or presentation at a conference
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The role of the near-infrared fluorescent dye on the pharmacokinetic behavior of fluorescent nanobody-based tracers for intra-operative cancer imaging
Declerck, N. (Speaker), Declercq, S. (Contributor), Debie, P. (Contributor), Du Ville, J. (Contributor), Mateusiak, L. (Contributor), Stroet, M. (Contributor), Akhtar, R. T. (Contributor), Luciano, M. (Contributor), Li, D.-H. (Contributor), Schnermann, M. J. (Contributor), Smith, B. (Contributor) & Hernot, S. (Contributor)
29 sep. 2022Activiteit: Talk or presentation at a conference
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Bimodal Nb-tracers for rapid and specific pre-and intra-operative cancer imaging
Declerck, N. (Speaker), Huygen, C. M. (Contributor), Mateusiak, L. (Contributor), Debie, P. (Contributor), van Willigen, D. M. (Contributor), van Leeuwen, F. W. B. (Contributor) & Hernot, S. (Speaker)
29 mei 2022 → 3 jun. 2022Activiteit: Talk or presentation at a conference
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Lymphatic mapping and surgical lymphadenectomy guidance using fluorescently labeled mannose-receptor-targeting nanobodies
Mateusiak, L. (Speaker), Debacker, J. (Contributor), Debie, P. (Contributor), Declerck, N. (Contributor), van Willigen, D. M. (Contributor), Raes, G. (Contributor), Mottrie, A. (Contributor), De Sutter, P. (Contributor), van Leeuwen, F. W. B. (Contributor), de Rooster, H. (Contributor) & Hernot, S. (Contributor)
15 mrt. 2022 → 18 mrt. 2022Activiteit: Talk or presentation at a conference
Scriptie
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Hybrid-labeled Nanobodies for intraoperative imaging: evaluation of two different labeling strategies.
Huygen, C. M. ((PhD) Student), Declerck, N. (Advisor) & Hernot, S. (Promotor), 2020Scriptie/Masterproef: Master's Thesis
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System xc- - deficiency does not affect the morphology of striatal medium spiny neurons
Declerck, N. ((PhD) Student) & Massie, A. (Promotor), Massie, A. (Promotor), 2019Scriptie/Masterproef: Master's Thesis