Projecten per jaar
Persoonlijk profiel
Expertise
Stem cell biology. Stem cell in vitro culture, qPCR, immunostaining, microscopy
Vingerafdruk
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Projecten
- 1 Afgelopen
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FWOTM1016: De impact van recurrente chromosomale afwijkingen op het groeivoordeel en de aanleg tot differentiatie van menselijke pluripotente stamcellen
Krivec, N. (Mandataris), Spits, C. (Administrative Promotor) & Sermon, K. (Co-Promoter)
1/11/20 → 31/10/24
Project: Fundamenteel
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1q gain bypasses the selective barrier against aneuploidy in RPE differentiation via wild-type co-culture rescue
Couvreu De Deckersberg, E., Lei, Y., Krivec, N., Huyghebaert, A., Duong, M. C., Janssens, C., Regin, M., Tsuiko, O., Movahedi, K., Verhulst, S., van Grunsven, L. A., Sermon, K., Al Delbany, D. & Spits, C., 25 nov. 2025, In: Nature Communications. 16, 1, 15 blz., 11627.Onderzoeksoutput: Article › peer review
Open Access -
Aneuploidy as a first genetic hit that enhances the tumorigenic capacity of differentiated human pluripotent stem cells
Al Delbany, D., Mampay, M., Srinivasan, A. N., Krivec, N., Huyghebaert, A., Movahedi, K. & Spits, C., 12 jun. 2025.Onderzoeksoutput: Poster
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Aneuploidy as a first genetic hit that enhances the tumorigenic capacity of differentiated human pluripotent stem cells
Al Delbany, D., Mampay, M., Srinivasan, A. N., Krivec, N., Huyghebaert, A., Movahedi, K. & Spits, C., 11 apr. 2025, (Unpublished).Onderzoeksoutput: Poster
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Aneuploidy as a first genetic hit that enhances the tumorigenic capacity of differentiated human pluripotent stem cells
Al Delbany, D., Mampay, M., Srinivasan, A. N., Krivec, N., Huyghebaert, A., Duong, M. C., Sarkar, A., Brock, S., Movahedi, K. & Spits, C., 28 nov. 2025.Onderzoeksoutput: Poster
Open Access -
A novel liver organoid model using directed mutagenesis to study the oncogenic potential of human pluripotent stem cell-derived hepatocytes
Huyghebaert, A., Al Delbany, D., Krivec, N., van Grunsven, L. A. & Spits, C., 11 apr. 2025, (Unpublished).Onderzoeksoutput: Poster
Datasets
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De Novo Cancer Mutations Frequently Associate with Recurrent Chromosomal Abnormalities during Long-Term Human Pluripotent Stem Cell Culture
Spits, C. (Creator), Al Delbany, D. (Creator), Ghosh, M. (Creator), Krivec, N. (Creator), Huyghebaert, A. (Creator), Regin, M. (Creator), Duong, C. M. (Creator), Lei, Y. (Creator), Sermon, K. (Creator) & Olsen, C. (Creator), VUB Institutional Data Repository, 15 okt. 2025
Dataset
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Loss of 18q Alters TGFβ Signalling Affecting Anteroposterior Neuroectodermal Fate in Human Embryonic Stem Cells
Spits, C. (Creator), Lei, Y. (Creator), Regin, M. (Creator), Krivec, N. (Creator), Huyghebaert, A. (Creator), Couvreu De Deckersberg, E. (Creator), Sermon, K. (Creator), Al Delbany, D. (Creator), Duong, C. M. (Creator) & Janssens, C. (Creator), VUB Institutional Data Repository, 10 okt. 2025
Dataset
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SALL3 mediates the loss of neuroectodermal differentiation potential in human embryonic stem cells with chromosome 18q loss (OPEN)
Spits, C. (Creator), Lei, Y. (Creator), Al Delbany, D. (Creator), Krivec, N. (Creator), Regin, M. (Creator), Couvreu De Deckersberg, E. (Creator), Janssens, C. (Creator), Ghosh, M. (Creator) & Sermon, K. (Creator), VUB Institutional Data Repository, 10 okt. 2025
Dataset
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SALL3 mediates the loss of neuroectodermal differentiation potential in human embryonic stem cells with chromosome 18q loss (RESTRICTED)
Spits, C. (Creator), Lei, Y. (Creator), Al Delbany, D. (Creator), Krivec, N. (Creator), Regin, M. (Creator), Couvreu De Deckersberg, E. (Creator), Janssens, C. (Creator), Ghosh, M. (Creator) & Sermon, K. (Creator), VUB Institutional Data Repository, 10 okt. 2025
Dataset
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Gain of 1q confers an MDM4-driven growth advantage to undifferentiated and differentiating hESC while altering their differentiation capacity
Spits, C. (Creator), Krivec, N. (Creator), Al Delbany, D. (Creator), Regin, M. (Creator), Lei, Y. (Creator), Sermon, K. (Creator), Couvreu De Deckersberg, E. (Creator), van Grunsven, L. (Creator) & Verhulst, S. (Creator), VUB Institutional Data Repository, 9 mei 2025
Dataset
Activiteiten
- 1 Talk or presentation at a conference
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SALL3 drives selective growth advantage and modulates pluripotency in hPSCs with chromosome 18q loss
Duong, C. M. (Presenter), Krivec, N. (Contributor), Al Delbany, D. (Contributor), Huyghebaert, A. (Contributor) & Spits, C. (Contributor)
28 nov. 2025Activiteit: Talk or presentation at a conference
Scriptie
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Study the effect of chromosomal abnormalities on the neuroectoderm differentiation of hESCs in two and three-dimensional culture systems
Asadi, R. ((PhD) Student), Al Delbany, D. (Co-promotor), Krivec, N. (Co-promotor) & Spits, C. (Promotor), 28 jul. 2024Scriptie/Masterproef: Master's Thesis