Projecten per jaar
Persoonlijk profiel
Expertise
Expertise: Tumor immunology.
We evaluate the use of single domain antibodies (sdAbs), also known as nanobodies, as targeting moieties for therapeutic and diagnostic applications.
Vingerafdruk
- 1 Soortgelijke profielen
Netwerk
Projecten
- 2 Afgelopen
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FWOSB43: Nanobody gemedieerde beeldvorming en blokkering van de inhiberende receptor LAG-3
Lecocq, Q., Breckpot, K., Devoogdt, N. & Keyaerts, M.
1/01/18 → 31/12/21
Project: Fundamenteel
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ANI173: Nanobody-mediated imaging and blocking of the inhibitory receptor LAG3.
1/10/16 → 30/09/17
Project: Fundamenteel
Onderzoeksoutput
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Targeted radionuclide therapy with low and high-dose Lutetium-177 labeled single domain antibodies induces distinct immune signatures in a mouse melanoma model
Ertveldt, T., De Beck, L., De Ridder, K., Locy, H., De Mey, W., Goyvaerts, C., Lecocq, Q., Ceuppens, H., De Vlaeminck, Y., Awad, R. M., Keyaerts, M., Devoogdt, N., D'Huyvetter, M., Breckpot, K. & Krasniqi, A., 2022, In : Molecular Cancer Therapeutics.Onderzoeksoutput: Article
Open Access -
TNF-α-Secreting Lung Tumor-Infiltrated Monocytes Play a Pivotal Role During Anti-PD-L1 Immunotherapy
De Ridder, K., Locy, H., Piccioni, E., Zuazo, M. I., Awad, R. M., Verhulst, S., Van Bulck, M., De Vlaeminck, Y., Lecocq, Q., Reijmen, E., De Mey, W., De Beck, L., Ertveldt, T., Pintelon, I., Timmermans, J-P., Escors, D., Keyaerts, M., Breckpot, K. & Goyvaerts, C., 14 apr 2022, In : Frontiers in Immunology. 13, blz. 811867 811867.Onderzoeksoutput: Article
Open Access -
Evaluation of single domain antibodies as nuclear tracers for imaging of the immune checkpoint receptor human lymphocyte activation gene-3 in cancer
Lecocq, Q., Debie, P., Puttemans, J., Awad, R. M., De Beck, L., Ertveldt, T., De Vlaeminck, Y., Goyvaerts, C., Raes, G., Keyaerts, M., Breckpot, K. & Devoogdt, N., 2 nov 2021, In : EJNMMI Research. 11, 1, 13 blz., 115.Onderzoeksoutput: Article
Open AccessBestand1 Citaat (Scopus)45 Downloads (Pure) -
Formatting and gene-based delivery of a human PD-L1 single domain antibody for immune checkpoint blockade
Awad, R. M., Lecocq, Q., Zeven, K., Ertveldt, T., De Beck, L., Ceuppens, H., Broos, K., De Vlaeminck, Y., Goyvaerts, C., Verdonck, M., Raes, G., Van Parys, A., Cauwels, A., Keyaerts, M., Devoogdt, N. & Breckpot, K., 10 sep 2021, In : Molecular Therapy: Methods & Clinical Development. 22, 9, blz. 172-182 11 blz., 10.Onderzoeksoutput: Article
Open AccessBestand2 Citaten (Scopus)41 Downloads (Pure) -
Gene-based delivery of human PD-L1 single domain antibody formats for immune checkpoint blockade
Awad, R. M., Lecocq, Q., Zeven, K., Ertveldt, T., De Beck, L., Ceuppens, H., Broos, K., De Vlaeminck, Y., Goyvaerts, C., Verdonck, M., Raes, G., Van Parys, A., Cauwels, A., Keyaerts, M., Devoogdt, N. & Breckpot, K., 22 feb 2021.Onderzoeksoutput: Unpublished abstract
Open AccessBestand28 Downloads (Pure)
Prijzen
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Best Presentation Award @ ORC day 18/11/2019
Quentin Lecocq (Recipient), 18 nov 2019
Prijs: Prize (including medals and awards)
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Certificat of Young Speaker Award
Quentin Lecocq (Recipient), Katrijn Broos (Recipient), Jessica Bridoux (Recipient), Geert Raes (Recipient), Catarina Xavier (Recipient), Nick Devoogdt (Recipient), Marleen Keyaerts (Recipient) & Karine Breckpot (Recipient), 1 feb 2019
Prijs: Prize (including medals and awards)
Bestand -
CIMT Travel Award 2019
Quentin Lecocq (Recipient), 21 mei 2019
Prijs: Prize (including medals and awards)
Bestand -
ESMI presentation award for best oral presentation
Jessica Bridoux (Recipient), Katrijn Broos (Recipient), Quentin Lecocq (Recipient), Maxine Crauwels (Recipient), Charlotte Martin (Recipient), Frederik Cleeren (Recipient), Mikhail Kondrashov (Recipient), Steven Ballet (Recipient), G. Bormans (Recipient), Magnus Schou (Recipient), Chad Elmore (Recipient), Geert Raes (Recipient), Karine Breckpot (Recipient), Serge Muyldermans (Recipient), Nick Devoogdt (Recipient), Marleen Keyaerts (Recipient), Vicky Caveliers (Recipient) & Catarina Xavier (Recipient), 17 jan 2020
Prijs: Prize (including medals and awards)
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Knowledge for Growth 2018 Ghent - poster award
Katrijn Broos (Recipient), Quentin Lecocq (Recipient), Jessica Bridoux (Recipient), Geert Raes (Recipient), Catarina Xavier (Recipient), Marleen Keyaerts (Recipient), Nick Devoogdt (Recipient) & Karine Breckpot (Recipient), 18 mei 2018
Prijs: Prize (including medals and awards)
Activiteiten
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Using the site-specific radiolabeling of a PD-L1 nanobody via maleimide–cysteine chemistry to develop a PET-tracer as screening tool for personalized oncology treatment
Dora Mugoli Chigoho (Speaker), Jessica Bridoux (Speaker), Catarina Xavier (Speaker), Vicky Caveliers (Speaker), Marleen Keyaerts (Speaker), Nick Devoogdt (Speaker), Karine Breckpot (Speaker), Robin Maximilian Awad (Speaker), Quentin Lecocq (Speaker)7 mei 2022Activiteit: Talk or presentation at a conference
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Nanobody-mediated imaging of the immune checkpoint LAG-3
Quentin Lecocq (Speaker)18 jan 2021Activiteit: Talk or presentation at a workshop/seminar
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Noninvasive imaging and inhibition of human programmed death ligand 1 (PD-L1) using nanobody K2 to improve cancer immunotherapy
Robin Maximilian Awad (Contributor), Dora Mugoli Chigoho (Contributor), Katrijn Broos (Contributor), Quentin Lecocq (Contributor), Katty Zeven (Contributor), Thomas Ertveldt (Contributor), Lien De Beck (Contributor), Hannelore Ceuppens (Contributor), Yannick De Vlaeminck (Contributor), Cleo Goyvaerts (Contributor), Steve Schoonooghe (Contributor), Vicky Caveliers (Contributor), Catarina Xavier (Contributor), Jessica Bridoux (Contributor), Geert Raes (Contributor), Marleen Keyaerts (Contributor), Nick Devoogdt (Contributor), Karine Breckpot (Speaker)25 okt 2021 → 26 okt 2021Activiteit: Talk or presentation at a conference
Bestand -
Nanobody-mediated imaging of the immune checkpoint LAG-3
Quentin Lecocq (Speaker)4 feb 2021Activiteit: Talk or presentation at a workshop/seminar
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2020-73
Nick Devoogdt (Supervisor), Karine Breckpot (Contributor), Quentin Lecocq (Contributor)2020Activiteit: Other
Knipsels
Scriptie
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Evaluation of single domain antibodies against the immune checkpoint LAG-3 for noninvasive nuclear imaging and therapy of cancer
Auteur: Devoogdt, N., Zeven, K. & Breckpot, K., 20 jun 2019Begeleider: Lecocq, Q. (Promotor)
Scriptie/masterproef: Master's Thesis
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Nanobody-mediated imaging and blocking of the inhibitory receptor LAG-3
Auteur: Lecocq, Q., Breckpot, K., Devoogdt, N. & Keyaerts, M., 2021Begeleider: Breckpot, K. (Promotor), Devoogdt, N. (Promotor) & Keyaerts, M. (Co-promotor)
Scriptie/masterproef: Doctoral Thesis
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Nanobody-mediated imaging and inhibition of the Immune checkpoint ligand PD-L1
Auteur: Breckpot, K. & Lecocq, Q., 16 jun 2016Begeleider: Devoogdt, N. (Promotor), Keyaerts, M. (Promotor) & Broos, K. (Promotor)
Scriptie/masterproef: Master's Thesis
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Nanobody-mediated imaging and inhibition of the immune checkpoint ligans PD-L1
Auteur: Lecocq, Q., Breckpot, K., Devoogdt, N. & Hernot, S., 16 jun 2016Scriptie/masterproef: Master's Thesis