Projecten per jaar
Persoonlijk profiel
Expertise
Expertise: Tumor immunology.
We evaluate the use of single domain antibodies (sdAbs), also known as nanobodies, as targeting moieties for therapeutic and diagnostic applications.
Vingerafdruk
- 1 Soortgelijke profielen
Netwerk
Projecten
- 2 Afgelopen
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FWOSB43: Nanobody gemedieerde beeldvorming en blokkering van de inhiberende receptor LAG-3
Lecocq, Q., Breckpot, K., Devoogdt, N. & Keyaerts, M.
1/01/18 → 31/12/21
Project: Fundamenteel
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ANI173: Nanobody-mediated imaging and blocking of the inhibitory receptor LAG3.
1/10/16 → 30/09/17
Project: Fundamenteel
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Emerging applications of nanobodies in cancer therapy
Awad, R. M., Meeus, F., Ceuppens, H., Ertveldt, T., Hanssens, H., Lecocq, Q., Mateusiak, L., Zeven, K., Valenta, H., De Groof, T. W. M., De Vlaeminck, Y., Krasniqi, A., De Veirman, K., Goyvaerts, C., D'Huyvetter, M., Hernot, S., Devoogdt, N. & Breckpot, K., 2022, In: International review of cell and molecular biology. 369, blz. 143-199 57 blz.Onderzoeksoutput: Article › peer review
Bestand1 Citaat (Scopus)99 Downloads (Pure) -
Inhibiting Histone and DNA Methylation Improves Cancer Vaccination in an Experimental Model of Melanoma
De Beck, L., Awad, R. M., Basso, V., Casares, N., De Ridder, K., De Vlaeminck, Y., Gnata, A., Goyvaerts, C., Lecocq, Q., San José-Enériz, E., Verhulst, S., Maes, K., Vanderkerken, K., Agirre, X., Prosper, F., Lasarte, J. J., Mondino, A. & Breckpot, K., 12 mei 2022, In: Frontiers in Immunology. 13, 15 blz., 799636.Onderzoeksoutput: Article › peer review
Open Access -
Targeted alpha therapy using Actinium-225 radiolabeled single domain antibodies induces antigen-specific immune responses and instills immunomodulation both systemically and at the tumor microenvironment
Ertveldt, T., Breckpot, K., Devoogdt, N., Puttemans, J., De Veirman, K., Krasniqi, A., Ceuppens, H., Dekempeneer, Y., De Jonghe, K., de Mey, W., Lecocq, Q., De Vlaeminck, Y., Awad, R. M., Goyvaerts, C., Keyaerts, M., D'Huyvetter, M., Bruchertseifer, F. & Morgenstern, A., 6 dec 2022, (Accepted/In press) Journal of Nuclear Medicine.Onderzoeksoutput: Article › Specialist
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Targeted radionuclide therapy with low and high-dose Lutetium-177 labeled single domain antibodies induces distinct immune signatures in a mouse melanoma model
Ertveldt, T., De Beck, L., De Ridder, K., Locy, H., De Mey, W., Goyvaerts, C., Lecocq, Q., Ceuppens, H., De Vlaeminck, Y., Awad, R. M., Keyaerts, M., Devoogdt, N., D'Huyvetter, M., Breckpot, K. & Krasniqi, A., jul 2022, In: Molecular Cancer Therapeutics. 21, 7, blz. 1136-1148 13 blz.Onderzoeksoutput: Article › peer review
Open AccessBestand4 Downloads (Pure) -
TNF-alpha-Secreting Lung Tumor-Infiltrated Monocytes Play a Pivotal Role During Anti-PD-L1 Immunotherapy
De Ridder, K., Locy, H., Piccioni, E., Zuazo, M. I., Awad, R. M., Verhulst, S., Van Bulck, M., De Vlaeminck, Y., Lecocq, Q., Reijmen, E., De Mey, W., De Beck, L., Ertveldt, T., Pintelon, I., Timmermans, J-P., Escors, D., Keyaerts, M., Breckpot, K. & Goyvaerts, C., 14 apr 2022, In: Frontiers in Immunology. 13, 15 blz., 811867.Onderzoeksoutput: Article › peer review
Open AccessBestand2 Citaten (Scopus)18 Downloads (Pure)
Prijzen
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Best Presentation Award @ ORC day 18/11/2019
Lecocq, Quentin (Recipient), 18 nov 2019
Prijs: Prize (including medals and awards)
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Certificat of Young Speaker Award
Lecocq, Quentin (Recipient), Broos, K. (Recipient), Bridoux, Jessica (Recipient), Raes, Geert (Recipient), Xavier, Catarina (Recipient), Devoogdt, Nick (Recipient), Keyaerts, Marleen (Recipient) & Breckpot, Karine (Recipient), 1 feb 2019
Prijs: Prize (including medals and awards)
Bestand -
CIMT Travel Award 2019
Lecocq, Quentin (Recipient), 21 mei 2019
Prijs: Prize (including medals and awards)
Bestand -
ESMI presentation award for best oral presentation
Bridoux, Jessica (Recipient), Broos, K. (Recipient), Lecocq, Quentin (Recipient), Crauwels, M. (Recipient), Martin, Charlotte (Recipient), Cleeren, F. (Recipient), Kondrashov, M. (Recipient), Ballet, Steven (Recipient), Bormans, G. (Recipient), Schou, M. (Recipient), Elmore, C. (Recipient), Raes, Geert (Recipient), Breckpot, Karine (Recipient), Muyldermans, Serge (Recipient), Devoogdt, Nick (Recipient), Keyaerts, Marleen (Recipient), Caveliers, Vicky (Recipient) & Xavier, Catarina (Recipient), 17 jan 2020
Prijs: Prize (including medals and awards)
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Knowledge for Growth 2018 Ghent - poster award
Broos, K. (Recipient), Lecocq, Quentin (Recipient), Bridoux, Jessica (Recipient), Raes, Geert (Recipient), Xavier, Catarina (Recipient), Keyaerts, Marleen (Recipient), Devoogdt, Nick (Recipient) & Breckpot, Karine (Recipient), 18 mei 2018
Prijs: Prize (including medals and awards)
Activiteiten
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Using the site-specific radiolabeling of a PD-L1 nanobody via maleimide–cysteine chemistry to develop a PET-tracer as screening tool for personalized oncology treatment
Dora Mugoli Chigoho (Speaker), Jessica Bridoux (Speaker), Catarina Xavier (Speaker), Vicky Caveliers (Speaker), Marleen Keyaerts (Speaker), Nick Devoogdt (Speaker), Karine Breckpot (Speaker), Robin Maximilian Awad (Speaker) & Quentin Lecocq (Speaker)
7 mei 2022Activiteit: Talk or presentation at a conference
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Nanobody-mediated imaging of the immune checkpoint LAG-3
Quentin Lecocq (Speaker)
18 jan 2021Activiteit: Talk or presentation at a workshop/seminar
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Nanobody-mediated imaging of the immune checkpoint LAG-3
Quentin Lecocq (Speaker)
4 feb 2021Activiteit: Talk or presentation at a workshop/seminar
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Noninvasive imaging and inhibition of human programmed death ligand 1 (PD-L1) using nanobody K2 to improve cancer immunotherapy
Robin Maximilian Awad (Contributor), Dora Mugoli Chigoho (Contributor), Katrijn Broos (Contributor), Quentin Lecocq (Contributor), Katty Zeven (Contributor), Thomas Ertveldt (Contributor), Lien De Beck (Contributor), Hannelore Ceuppens (Contributor), Yannick De Vlaeminck (Contributor), Cleo Goyvaerts (Contributor), Steve Schoonooghe (Contributor), Vicky Caveliers (Contributor), Catarina Xavier (Contributor), Jessica Bridoux (Contributor), Geert Raes (Contributor), Marleen Keyaerts (Contributor), Nick Devoogdt (Contributor) & Karine Breckpot (Speaker)
25 okt 2021 → 26 okt 2021Activiteit: Talk or presentation at a conference
Bestand -
2020-73
Nick Devoogdt (Supervisor), Karine Breckpot (Contributor) & Quentin Lecocq (Contributor)
2020Activiteit: Other
Knipsels
Scriptie
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Nanobody-mediated imaging and blocking of the inhibitory receptor LAG-3
Auteur: Lecocq, Q., Breckpot, K., Devoogdt, N. & Keyaerts, M., 23 nov 2021Begeleider: Breckpot, K. (Promotor), Devoogdt, N. (Promotor) & Keyaerts, M. (Co-promotor)
Scriptie/Masterproef: Doctoral Thesis
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Nanobody-mediated imaging and inhibition of the Immune checkpoint ligand PD-L1
Auteur: Breckpot, K. & Lecocq, Q., 16 jun 2016Begeleider: Devoogdt, N. (Promotor), Keyaerts, M. (Promotor) & Broos, K. (Promotor)
Scriptie/Masterproef: Master's Thesis
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Nanobody-mediated imaging and inhibition of the immune checkpoint ligans PD-L1
Auteur: Lecocq, Q., Breckpot, K., Devoogdt, N. & Hernot, S., 16 jun 2016Scriptie/Masterproef: Master's Thesis