Projecten per jaar
Persoonlijk profiel
Expertise
- Fundamental Research in Eukaryotic Gene Expression. Protein-DNA interaction. Protein Structure and Action. (X-ray crystallography) Antibody Engineering. Protein engineering. (Site directed mutagenesis/Enzym kinetics).
- Cloning and production of recombinant antibody fragments derived from camelidae
Vingerafdruk
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Projecten
- 51 Afgelopen
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IOFPOC51: IOF POC Project SYNALI : Ontwikkeling en toepassing van een Synthetische Nanobody Bibliotheek
Devoogdt, N. (Administrative Promotor), Muyldermans, S. (Co-Promoter), Sterckx, Y. (Co-Promoter) & Caljon, G. (Co-Promoter)
1/01/22 → 25/04/25
Project: Toegepast
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SRP50: SRP-Onderzoekszwaartepunt: Exploiting Peptides: Protein Binders, Modulators and Inhibitors for Imaging and Therapy [Exploit-PeptIT]
Ballet, S. (Administrative Promotor), Caveliers, V. (Co-Promoter), Hernot, S. (Co-Promoter), Versées, W. (Co-Promoter), Vinken, M. (Co-Promoter), Muyldermans, S. (Co-Promoter), Devoogdt, N. (Co-Promoter), Bridoux, J. (Medewerker) & Martin, C. (Medewerker)
1/03/19 → 30/09/25
Project: Fundamenteel
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FWOAL879: 'Nanobody'-gebaseerde inhibitoren van connexine hemikanalen en pannexine kanalen als nieuwe therapeutica voor de behandeling van inflammatoire aandoeningen in de lever en het cardiovasculair systeem.
Vinken, M. (Administrative Promotor), Muyldermans, S. (Co-Promoter) & Kwak, B. R. (Co-Promoter)
1/01/18 → 31/12/21
Project: Fundamenteel
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ANI192: Evaluatie van het theranostic potentieel van Nanobodies tegen Acute myeloïde leukemie stamcel Markers
Muyldermans, S. (Administrative Promotor), Romao, E. (Medewerker) & Devoogdt, N. (Co-Promoter)
1/10/17 → 14/11/18
Project: Fundamenteel
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FWOAL856: ERA-NET NEURON cofund JTC 2016: 'Ruggenmerg herstelling door endogene stamcellen uit de spinale niche'
Muyldermans, S. (Administrative Promotor)
1/07/17 → 30/06/19
Project: Fundamenteel
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Allosteric inhibition of trypanosomatid pyruvate kinases by a camelid single-domain antibody
Pinto Torres, J. E., Claes, M., Hendrickx, R., Yuan, M., Smiejkowska, N., Van Wielendaele, P., Hacisuleyman, A., De Winter, H., Muyldermans, S., Michels, P. A. M., Walkinshaw, M. D., Versées, W., Caljon, G., Magez, S. & Sterckx, Y.G.-J., 31 mrt. 2025, In: eLife. 13, 27 blz.Onderzoeksoutput: Article › peer review
Open AccessBestand36 Downloads (Pure) -
Evidence for a model of conformational change by the Plasmodium falciparum circumsporozoite protein during sporozoite development in the mosquito host through the use of camelid single-domain antibodies.
Geens, R., De Vocht, L., Aguirre-Botero, M. C., Vincke, C., Romão, E., Magez, S., Muyldermans, S., Amino, R. & Sterckx, Y.G.-J., jun. 2025, In: Infection and Immunity. 93, 6, 19 blz., e0008125.Onderzoeksoutput: Article › peer review
Open AccessBestand7 Downloads (Pure) -
Integrating in vitro screening in drug development to reduce animal use: a case approach
Van Campenhout, R., De Groof, T., Kadam, P., Kwak, B. R., Muyldermans, S., Devoogdt, N. & Vinken, M., 15 sep. 2025. 1 blz.Onderzoeksoutput: Poster
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Nanobody-based Pannexin1 channel inhibitors increase survival after cardiac ischemia/reperfusion
Rusiecka, O. M., Molica, F., Clochard, L., Van Campenhout, R., De Groof, T., Bes, V., Devoogdt, N., Muyldermans, S., Vinken, M. & Kwak, B. R., 2025, In: Cell and Tissue Research. 402, 1, blz. 121-137 17 blz.Onderzoeksoutput: Article › peer review
Open Access1 Citaat (Scopus) -
Nanobody-based pannexin1 channel inhibitors reduce inflammation in acute liver injury
Van Campenhout, R., De Groof, T., Kadam, P., Kwak, B. R., Muyldermans, S., Devoogdt, N. & Vinken, M., 9 mei 2025. 1 blz.Onderzoeksoutput: Poster
Datasets
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Nanobody-based pannexin1 channel inhibitors reduce inflammation in acute liver injury
Van Campenhout, R. (Creator), De Groof, T. (Creator), Kadam, P. (Researcher), Muyldermans, S. (Supervisor), Devoogdt, N. (Supervisor) & Vinken, M. (Supervisor), Journal of Nanobiotechnology, 2023
DOI: 10.1186/s12951-023-02137-1
Dataset
Prijzen
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ESMI presentation award for best oral presentation
Bridoux, J. (Recipient), Broos, K. (Recipient), Lecocq, Q. (Recipient), Crauwels, M. (Recipient), Martin, C. (Recipient), Cleeren, F. (Recipient), Kondrashov, M. (Recipient), Ballet, S. (Recipient), Bormans, G. (Recipient), Schou, M. (Recipient), Elmore, C. (Recipient), Raes, G. (Recipient), Breckpot, K. (Recipient), Muyldermans, S. (Recipient), Devoogdt, N. (Recipient), Keyaerts, M. (Recipient), Caveliers, V. (Recipient) & Xavier, C. (Recipient), 17 jan. 2020
Prijs: Prize (including medals and awards)
Activiteiten
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Development and testing of nanobody-based drug candidates for the treatment of liver inflammation
Peeters, D. (Presenter), De Groof, T. (Contributor), Kadam, P. (Contributor), Kwak, B. R. (Contributor), Muyldermans, S. (Contributor), Devoogdt, N. (Contributor), Vinken, M. (Contributor) & Van Campenhout, R. (Contributor)
15 mei 2025Activiteit: Talk or presentation at a conference
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Nanobody-based pannexin1 channel inhibitors reduce inflammation in acute liver injury
Van Campenhout, R. (Speaker), De Groof, T. (Contributor), Kadam, P. (Contributor), Kwak, B. R. (Contributor), Muyldermans, S. (Contributor), Devoogdt, N. (Contributor) & Vinken, M. (Contributor)
24 jul. 2024 → 31 jul. 2024Activiteit: Talk or presentation at a conference
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Nanobody-based Panx1 channel inhibitors reduce inflammation in acute liver injury
Peeters, D. (Presenter), De Groof, T. (Contributor), Kadam, P. (Contributor), Kwak, B. R. (Contributor), Muyldermans, S. (Contributor), Devoogdt, N. (Contributor), Van Campenhout, R. (Contributor) & Vinken, M. (Contributor)
7 okt. 2024Activiteit: Talk or presentation at a conference
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Biomolecules (Tijdschrift)
Devoogdt, N. (Editor), Muyldermans, S. (Editor), De Groof, T. (Editor) & Hernot, S. (Editor)
2021 → …Activiteit: Editorial activity
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Immuno-PET imaging using the hPD-L1 Nanobody: Radiolabelling strategies
Bridoux, J. (Speaker), Broos, K. (Contributor), Lecocq, Q. (Contributor), Crauwels, M. (Contributor), Martin, C. (Contributor), Cleeren, F. (Contributor), Krivoshapov, M. (Speaker), Ballet, S. (Speaker), Bormans, G. (Speaker), Raes, G. (Speaker), Breckpot, K. (Speaker), Muyldermans, S. (Speaker), Schou, M. (Speaker), Elmore, C. (Speaker), Devoogdt, N. (Speaker), Caveliers, V. (Speaker), Keyaerts, M. (Speaker) & Xavier, C. (Speaker)
14 jan. 2020Activiteit: Talk or presentation at a conference
Scriptie
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Bead based immunoassay of HER2 ECD domain using nanobodies
Adaga, E. ((PhD) Student), Muyldermans, S. (Promotor), De Pauw, P. (Co-promotor) & Devoogdt, N. (Jury), 1 sep. 2015Scriptie/Masterproef: Master's Thesis
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Conversion of Nanobodies to Fluorescent probes with conserved size and functionality
Nguyen, T. N. H. ((PhD) Student), Xavier, C. (Jury), Muyldermans, S. (Promotor) & Pauw, De, P. (Advisor), 5 sep. 2014Scriptie/Masterproef: Master's Thesis
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Development of novel fluorescent reporters for Sulfolobus acidocaldarius and their application to build a biosensor strain
Linussio, J. ((PhD) Student), Peeters, E. (Promotor), Willaert, R. (Jury) & Muyldermans, S. (Jury), Sybers, D. (Advisor), 27 jun. 2016Scriptie/Masterproef: Master's Thesis
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Diagnostic potential of a Nanobody directed against Trypanosoma congolense fructose-1,6-bisphosphate aldolase
Lee, F. ((PhD) Student), Muyldermans, S. (Jury), Van Ginderachter, J. (Jury), Sterckx, Y. (Co-promotor) & Magez, S. (Promotor), jun. 2016Scriptie/Masterproef: Master's Thesis
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Effect of different characteristics of radiometal labelled nanobodies on the kidney retention
Crauwels, M. ((PhD) Student), Xavier, C. (Promotor), Muyldermans, S. (Promotor) & Devoogdt, N. (Co-promotor), 26 okt. 2020Scriptie/Masterproef: Doctoral Thesis