Projecten per jaar
Persoonlijk profiel
Expertise
Development of radiopharmaceuticals for PET and radionuclide therapy applications based on camelid single domain antibody fragments (also called VHH or Nanobodies).
Optimization of (automated) radiolabeling procedures, purification methods and formulation. In vitro and in vivo evaluation of new radiopharmaceutical probes in terms of biodistribution, in vivo stability and targeting potential. Translation of preclinically validated tracers to early phase clinical trials, including fulfilling all regulatory requirements.
GMP manufacturing of radiopharmaceuticals.
Vingerafdruk
Verdiep u in de onderzoeksgebieden waarop Vicky Caveliers actief is. Deze onderwerplabels komen uit het werk van deze persoon. Samen vormen ze een unieke vingerafdruk.
- 1 Soortgelijke profielen
Netwerk
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
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FWOIRI10: Onderzoek op radioactieve kernen aan ISOLDE-CERN, SPIRAL2-GANIL and MEDICIS-CERN
Caveliers, V. & D'Huyvetter, M.
1/01/23 → 31/12/26
Project: Fundamenteel
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HERC59: PET camera voor beeldvorming van kleine proefdieren
Devoogdt, N., Raes, G., Lahoutte, T., Van Ginderachter, J., Caveliers, V., Keyaerts, M., Hernot, S. & D'Huyvetter, M.
1/05/22 → 30/04/26
Project: Fundamenteel
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FWOSB114: Ontwikkeling van een nieuwe chemo-enzymatische strategie voor de generatie van radioactief fluor-gemerkte PET-probes
Declercq, S., Devoogdt, N., Bridoux, J. & Caveliers, V.
1/11/21 → 8/02/24
Project: Fundamenteel
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IOF3018: GEAR: TOPGUN: Ontwikkeling van Peptidomimetische Theranostica en GMP productie platform
Ballet, S., Caveliers, V., Martin, C., Barlow, T. & Bridoux, J.
1/01/21 → 31/12/25
Project: Toegepast
Onderzoeksoutput
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A Realistic Multi-region Mouse Kidney Dosimetry Model to Support the Preclinical Evaluation of Potential Nephrotoxicity of Radiopharmaceutical Therapy
Saldarriaga Vargas, C., Struelens, L., D'Huyvetter, M., Caveliers, V. & Covens, P., 2022, In: Journal of Nuclear Medicine.Onderzoeksoutput: Article › peer review
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Assessment of Mouse-Specific Pharmacokinetics in Kidneys Based on 131I Activity Measurements Using Micro-SPECT
Saldarriaga Vargas, C., Struelens, L., D'Huyvetter, M., Caveliers, V. & Covens, P., 23 feb 2022, In: EJNMMI Physics. 9, 21 blz., 13.Onderzoeksoutput: Article › peer review
Open AccessBestand36 Downloads (Pure) -
Assessment of repeatability and uptake quantification of (68)GaNOTA-anti-HER2 sdAb PET/CT in patients with locally advanced or metastatic breast cancer
Gondry, O., Xavier, C., Waelput, W., Al Dabssi, O., Vanhoeij, M., Aspeslagh, S., Joris, S., Fontaine, C., Verfaillie, G., De Greve, J., Glorieus, K., Luyten, I., Vandenbroucke, F., Bourgeois, S., Raes, L., Thyparambil, S., Devoogdt, N., Vaneycken, I., Cousaert, J., Caveliers, V. & 3 anderen, , 15 feb 2022, In: Cancer Research. 82, 4, blz. P3-02-05Onderzoeksoutput: Meeting abstract (Journal)
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Impact of doubling peptide length on in vivo hydrogel stability and sustained drug release
Heremans, J., Chevillard, L., Mannes, M., Mangialetto, J., Leroy, K., White, J. F., Vinken, M., Gardiner, J., Van Mele, B., Van den Brande, N., Hoogenboom, R., Madder, A., Caveliers, V., Megarbane, B., Hernot, S., Ballet, S. & Martin, C., okt 2022, In: Journal of Controlled Release. 350, blz. 514-524 11 blz.Onderzoeksoutput: Article › peer review
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Preclinical evaluation of 225Ac-labeled single-domain antibody for the treatment of HER2pos cancer
Rodak, M., Dekempeneer, Y., Wojewódzka, M., Caveliers, V., Covens, P., Miller, B. W., Sevenois, M. B., Bruchertseifer, F., Morgenstern, A., Lahoutte, T., D'Huyvetter, M. & Pruszynski, M., 2 dec 2022, In: Molecular Cancer Therapeutics. 21, 12, blz. 1835-1845 11 blz.Onderzoeksoutput: Article › peer review
Open Access
Prijzen
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ESMI presentation award for best oral presentation
Bridoux, Jessica (Recipient), Broos, K. (Recipient), Lecocq, Quentin (Recipient), Crauwels, M. (Recipient), Martin, Charlotte (Recipient), Cleeren, F. (Recipient), Kondrashov, M. (Recipient), Ballet, Steven (Recipient), Bormans, G. (Recipient), Schou, M. (Recipient), Elmore, C. (Recipient), Raes, Geert (Recipient), Breckpot, Karine (Recipient), Muyldermans, Serge (Recipient), Devoogdt, Nick (Recipient), Keyaerts, Marleen (Recipient), Caveliers, Vicky (Recipient) & Xavier, Catarina (Recipient), 17 jan 2020
Prijs: Prize (including medals and awards)
Activiteiten
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Preclinical validation of [18F]-FB-(Anti Human PD-L1) Nanobody for PET imaging
Herlinde Dierick (Speaker), Karine Breckpot (Contributor), Nick Devoogdt (Contributor), Marleen Keyaerts (Contributor), Vicky Caveliers (Contributor), Tony Lahoutte (Contributor) & Jessica Bridoux (Contributor)
7 mei 2022Activiteit: Talk or presentation at a conference
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Using the site-specific radiolabeling of a PD-L1 nanobody via maleimide–cysteine chemistry to develop a PET-tracer as screening tool for personalized oncology treatment
Dora Mugoli Chigoho (Speaker), Jessica Bridoux (Speaker), Catarina Xavier (Speaker), Vicky Caveliers (Speaker), Marleen Keyaerts (Speaker), Nick Devoogdt (Speaker), Karine Breckpot (Speaker), Robin Maximilian Awad (Speaker) & Quentin Lecocq (Speaker)
7 mei 2022Activiteit: Talk or presentation at a conference
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Noninvasive imaging and inhibition of human programmed death ligand 1 (PD-L1) using nanobody K2 to improve cancer immunotherapy
Robin Maximilian Awad (Contributor), Dora Mugoli Chigoho (Contributor), Katrijn Broos (Contributor), Quentin Lecocq (Contributor), Katty Zeven (Contributor), Thomas Ertveldt (Contributor), Lien De Beck (Contributor), Hannelore Ceuppens (Contributor), Yannick De Vlaeminck (Contributor), Cleo Goyvaerts (Contributor), Steve Schoonooghe (Contributor), Vicky Caveliers (Contributor), Catarina Xavier (Contributor), Jessica Bridoux (Contributor), Geert Raes (Contributor), Marleen Keyaerts (Contributor), Nick Devoogdt (Contributor) & Karine Breckpot (Speaker)
25 okt 2021 → 26 okt 2021Activiteit: Talk or presentation at a conference
Bestand -
Immuno-PET imaging using the hPD-L1 Nanobody: Radiolabelling strategies
Jessica Bridoux (Speaker), Katrijn Broos (Contributor), Quentin Lecocq (Contributor), Maxine Crauwels (Contributor), Charlotte Martin (Contributor), Frederik Cleeren (Contributor), Mikhail Krivoshapov (Speaker), Steven Ballet (Speaker), G. Bormans (Speaker), Geert Raes (Speaker), Karine Breckpot (Speaker), Serge Muyldermans (Speaker), Magnus Schou (Speaker), Chad Elmore (Speaker), Nick Devoogdt (Speaker), Vicky Caveliers (Speaker), Marleen Keyaerts (Speaker) & Catarina Xavier (Speaker)
14 jan 2020Activiteit: Talk or presentation at a conference
Knipsels
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Ontwikkeling van nanobodies voor de visualisatie van tumoren.
11/12/17
1 Mediabijdrage
Pers / media: !!Research
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Kikkers gebruiken moleculen als micro-giftanden om roofdieren te vergiftigen
Kim Roelants, Vicky Caveliers, Sophie Hernot & Cindy Peleman
16/11/17
1 Mediabijdrage
Pers / media: !!Research
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Tackling a shortage of PET scientists and improving healthcare
Jessica Bridoux, Vicky Caveliers & Catarina Xavier
1/10/17
1 Mediabijdrage
Pers / media: !!Research
Scriptie
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Amino acids in oncology diagnostics: Development of new PET probes targeting the glutamine transporter ASCT-2
Auteur: Baguet, T., De Vos, F., Van Calenbergh, S. & Caveliers, V., 3 jul 2020Scriptie/Masterproef: Doctoral Thesis
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A multistep manufacturing protocol for the site-specific radiolabeling of a nanobody with [18F]Al.
Auteur: Vanmarcke, S. G., Caveliers, V. & Bridoux, J., 13 jun 2018Scriptie/Masterproef: Master's Thesis
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Analysis of glutamate transporter expression in post mortem tissue of depressed patients
Auteur: Rubbens, N., Demuyser, T., Massie, A., Smolders, I. & Caveliers, V., 2016Begeleider: Demuyser, T. (Promotor)
Scriptie/Masterproef: Master's Thesis
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Bepaling van de plasmastabiliteit van een synthetisch peptide en preliminair onderzoek naar het minimaliseren van peptide-adsorptie tijdens microdialyse
Auteur: Van den Borre, L., Van Eeckhaut, A., Caveliers, V. & Doktorova, T., 10 jun 2015Scriptie/Masterproef: Master's Thesis
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Bepaling van de specifieke activiteit van cyclotron geproduceerd F18-fluoride en F18-gemerkt radiofarmacon
Auteur: Deprez, M., Caveliers, V., Blykers, A., De Kock, J. & Vander Heyden, Y., 10 jun 2015Scriptie/Masterproef: Master's Thesis