Projecten per jaar
Persoonlijk profiel
Expertise
Development of radiopharmaceuticals for PET and radionuclide therapy applications based on camelid single domain antibody fragments (also called VHH or Nanobodies).
Optimization of (automated) radiolabeling procedures, purification methods and formulation. In vitro and in vivo evaluation of new radiopharmaceutical probes in terms of biodistribution, in vivo stability and targeting potential. Translation of preclinically validated tracers to early phase clinical trials, including fulfilling all regulatory requirements.
GMP manufacturing of radiopharmaceuticals.
Vingerafdruk
Verdiep u in de onderzoeksgebieden waarop Vicky Caveliers actief is. Deze onderwerplabels komen uit het werk van deze persoon. Samen vormen ze een unieke vingerafdruk.
- 1 Soortgelijke profielen
Netwerk
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
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IOF3018: GEAR: TOPGUN: Ontwikkeling van Peptidomimetische Theranostica en GMP productie platform
Ballet, S., Caveliers, V., Martin, C. & Barlow, T.
1/01/21 → 31/12/25
Project: Toegepast
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FWOAL926: Moleculaire engineering van peptide gebaseerde hydrogelen voor vertraagde medicijnafgifte
Hoogenboom, R., Ballet, S., Martin, C. & Caveliers, V.
1/01/19 → 31/12/22
Project: Fundamenteel
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OZR3002: Toekenning EU-Beurs: EU-Cofinanciering B2b categorie Vicky Caveliers
18/10/16 → 18/10/20
Project: Fundamenteel
Onderzoeksoutput
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68Ga-Labeling: Laying the Foundation for an Anti-Radiolytic Formulation for NOTA-sdAb PET Tracers
Baudhuin, H., Cousaert, J., Vanwolleghem, P., Raes, G., Caveliers, V., Keyaerts, M., Lahoutte, T. & Xavier, C., 1 jan 2021, In : Pharmaceuticals. 14, 5, 16 blz., 448.Onderzoeksoutput: Article
Open Access -
Immunogenicity Risk Profile of Nanobodies
Ackaert, C., Smiejkowska, N., Xavier, C., Sterckx, Y. G. J., Denies, S., Stijlemans, B., Elkrim, Y., Devoogdt, N., Caveliers, V., Lahoutte, T., Muyldermans, S., Breckpot, K. & Keyaerts, M., 9 mrt 2021, In : Frontiers in Immunology. 12, 15 blz., 632687.Onderzoeksoutput: Article
Open AccessBestand15 Citaten (Scopus)76 Downloads (Pure) -
Lyophilization of NOTA-sdAbs: First step towards a cold diagnostic kit for 68Ga-labeling
Baudhuin, H., Van Bockstal, P-J., De Beer, T., Vaneycken, I., Bridoux, J., Raes, G., Caveliers, V., Keyaerts, M., Devoogdt, N., Lahoutte, T. & Xavier, C., sep 2021, In : European Journal of Pharmaceutics and Biopharmaceutics. 166, blz. 194-204 11 blz.Onderzoeksoutput: Article
Open AccessBestand14 Downloads (Pure) -
Phase I trial of 131I-GMIB-Anti-HER2-VHH1, a new promising candidate for HER2-targeted radionuclide therapy in breast cancer patients
D'Huyvetter, M., De Vos, J., Caveliers, V., Vaneycken, I., Heemskerk, J., Duhoux, F. P., Fontaine, C., Vanhoeij, M., Windhorst, A. D., van der Aa, F., Hendrikse, N. H., Eersels, J. L. E., Everaert, H., Gykiere, P., Devoogdt, N., Raes, G., Lahoutte, T. & Keyaerts, M., 1 aug 2021, In : Journal of Nuclear Medicine. 62, 8, blz. 1097-1105 9 blz.Onderzoeksoutput: Article
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Site-Specific Radiolabeling of a Human PD-L1 Nanobody via Maleimide-Cysteine Chemistry
Chigoho, D. M., Lecocq, Q., Awad, R. M., Breckpot, K., Devoogdt, N., Keyaerts, M., Caveliers, V., Xavier, C. & Bridoux, J., 8 jun 2021, In : Pharmaceuticals. 14, 6, 11 blz., 550.Onderzoeksoutput: Article
Open AccessBestand2 Citaten (Scopus)10 Downloads (Pure)
Prijzen
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ESMI presentation award for best oral presentation
Jessica Bridoux (Recipient), Katrijn Broos (Recipient), Quentin Lecocq (Recipient), Maxine Crauwels (Recipient), Charlotte Martin (Recipient), Frederik Cleeren (Recipient), Mikhail Kondrashov (Recipient), Steven Ballet (Recipient), G. Bormans (Recipient), Magnus Schou (Recipient), Chad Elmore (Recipient), Geert Raes (Recipient), Karine Breckpot (Recipient), Serge Muyldermans (Recipient), Nick Devoogdt (Recipient), Marleen Keyaerts (Recipient), Vicky Caveliers (Recipient) & Catarina Xavier (Recipient), 17 jan 2020
Prijs: Prize (including medals and awards)
Activiteiten
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Noninvasive imaging and inhibition of human programmed death ligand 1 (PD-L1) using nanobody K2 to improve cancer immunotherapy
Robin Maximilian Awad (Contributor), Dora Mugoli Chigoho (Contributor), Katrijn Broos (Contributor), Quentin Lecocq (Contributor), Katty Zeven (Contributor), Thomas Ertveldt (Contributor), Lien De Beck (Contributor), Hannelore Ceuppens (Contributor), Yannick De Vlaeminck (Contributor), Cleo Goyvaerts (Contributor), Steve Schoonooghe (Contributor), Vicky Caveliers (Contributor), Catarina Xavier (Contributor), Jessica Bridoux (Contributor), Geert Raes (Contributor), Marleen Keyaerts (Contributor), Nick Devoogdt (Contributor), Karine Breckpot (Speaker)25 okt 2021 → 26 okt 2021Activiteit: Talk or presentation at a conference
Bestand -
Immuno-PET imaging using the hPD-L1 Nanobody: Radiolabelling strategies
Jessica Bridoux (Speaker), Katrijn Broos (Contributor), Quentin Lecocq (Contributor), Maxine Crauwels (Contributor), Charlotte Martin (Contributor), Frederik Cleeren (Contributor), Mikhail Krivoshapov (Speaker), Steven Ballet (Speaker), G. Bormans (Speaker), Geert Raes (Speaker), Karine Breckpot (Speaker), Serge Muyldermans (Speaker), Magnus Schou (Speaker), Chad Elmore (Speaker), Nick Devoogdt (Speaker), Vicky Caveliers (Speaker), Marleen Keyaerts (Speaker), Catarina Xavier (Speaker)14 jan 2020Activiteit: Talk or presentation at a conference
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2020-74
Tony Lahoutte (Supervisor), Vicky Caveliers (Contributor), Catarina Xavier (Contributor), Jessica Bridoux (Contributor), Herlinde Dierick (Contributor)2020Activiteit: Other
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Preclinical development with Nanobodies with a focus on ovarian cancer
Vicky Caveliers (Speaker)1 mei 2019Activiteit: Talk or presentation at a conference
Knipsels
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Ontwikkeling van nanobodies voor de visualisatie van tumoren.
11/12/17
1 Mediabijdrage
Pers / media: !!Research
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Kikkers gebruiken moleculen als micro-giftanden om roofdieren te vergiftigen
Kim Roelants, Vicky Caveliers, Sophie Hernot & Cindy Peleman
16/11/17
1 Mediabijdrage
Pers / media: !!Research
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Tackling a shortage of PET scientists and improving healthcare
Jessica Bridoux, Vicky Caveliers & Catarina Xavier
1/10/17
1 Mediabijdrage
Pers / media: !!Research
Scriptie
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Amino acids in oncology diagnostics: Development of new PET probes targeting the glutamine transporter ASCT-2
Auteur: Baguet, T., De Vos, F., Van Calenbergh, S. & Caveliers, V., 3 jul 2020Scriptie/masterproef: Doctoral Thesis
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A multistep manufacturing protocol for the site-specific radiolabeling of a nanobody with [18F]Al.
Auteur: Vanmarcke, S. G., Caveliers, V. & Bridoux, J., 13 jun 2018Scriptie/masterproef: Master's Thesis
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Analysis of glutamate transporter expression in post mortem tissue of depressed patients
Auteur: Rubbens, N., Demuyser, T., Massie, A., Smolders, I. & Caveliers, V., 2016Begeleider: Demuyser, T. (Promotor)
Scriptie/masterproef: Master's Thesis
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Bepaling van de plasmastabiliteit van een synthetisch peptide en preliminair onderzoek naar het minimaliseren van peptide-adsorptie tijdens microdialyse
Auteur: Van den Borre, L., Van Eeckhaut, A., Caveliers, V. & Doktorova, T., 10 jun 2015Scriptie/masterproef: Master's Thesis
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Bepaling van de specifieke activiteit van cyclotron geproduceerd F18-fluoride en F18-gemerkt radiofarmacon
Auteur: Deprez, M., Caveliers, V., Blykers, A., De Kock, J. & Vander Heyden, Y., 10 jun 2015Scriptie/masterproef: Master's Thesis