Projecten per jaar
Persoonlijk profiel
Expertise
Development of radiopharmaceuticals for PET and radionuclide therapy applications based on camelid single domain antibody fragments (also called VHH or Nanobodies).
Optimization of (automated) radiolabeling procedures, purification methods and formulation. In vitro and in vivo evaluation of new radiopharmaceutical probes in terms of biodistribution, in vivo stability and targeting potential. Translation of preclinically validated tracers to early phase clinical trials, including fulfilling all regulatory requirements.
GMP manufacturing of radiopharmaceuticals.
Vingerafdruk
Verdiep u in de onderzoeksgebieden waarop Vicky Caveliers actief is. Deze onderwerplabels komen uit het werk van deze persoon. Samen vormen ze een unieke vingerafdruk.
- 12 Soortgelijke profielen
Netwerk
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
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IOF3018: GEAR: TOPGUN: Ontwikkeling van Peptidomimetische Theranostica en GMP productie platform
Ballet, S., Caveliers, V., Martin, C. & Barlow, T.
1/01/21 → 31/12/25
Project: Toegepast
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FWOAL926: Moleculaire engineering van peptide gebaseerde hydrogelen voor vertraagde medicijnafgifte
Hoogenboom, R., Ballet, S., Martin, C. & Caveliers, V.
1/01/19 → 31/12/22
Project: Fundamenteel
Onderzoeksoutput
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68Ga-Labeling: Laying the Foundation for an Anti-Radiolytic Formulation for NOTA-sdAb PET Tracers
Baudhuin, H., Cousaert, J., Vanwolleghem, P., Raes, G., Caveliers, V., Keyaerts, M., Lahoutte, T. & Xavier, C., 1 jan 2021, In : Pharmaceuticals. 14, 5, 16 blz., 448.Onderzoeksoutput: Article
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Immunogenicity Risk Profile of Nanobodies
Ackaert, C., Smiejkowska, N., Xavier, C., Sterckx, Y. G. J., Denies, S., Stijlemans, B., Elkrim, Y., Devoogdt, N., Caveliers, V., Lahoutte, T., Muyldermans, S., Breckpot, K. & Keyaerts, M., 9 mrt 2021, In : Frontiers in Immunology. 12, 15 blz., 632687.Onderzoeksoutput: Article
Open AccessBestand3 Citaten (Scopus)27 Downloads (Pure) -
Site-Specific Radiolabeling of a Human PD-L1 Nanobody via Maleimide-Cysteine Chemistry
Chigoho, D. M., Lecocq, Q., Awad, R. M., Breckpot, K., Devoogdt, N., Keyaerts, M., Caveliers, V., Xavier, C. & Bridoux, J., 8 jun 2021, In : Pharmaceuticals. 14, 6, blz. 550 550.Onderzoeksoutput: Article
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Anti-human PD-L1 Nanobody for Immuno-PET Imaging. IF(2019) 4,082: Validation of a Conjugation Strategy for Clinical Translation
Bridoux, J., Broos, K., Lecocq, Q., Debie, P., Martin, C., Ballet, S., Raes, G., Neyt, S., Vanhove, C., Breckpot, K., Devoogdt, N., Caveliers, V., Keyaerts, M. & Xavier, C., okt 2020, In : Biomolecules. 10, 10, blz. 1-15 15 blz., 1388.Onderzoeksoutput: Article
Open AccessBestand6 Citaten (Scopus)11 Downloads (Pure) -
Improved Detection of Molecular Markers of Atherosclerotic Plaques Using Sub-Millimeter PET Imaging
Bridoux, J., Neyt, S., Debie, P., Descamps, B., Devoogdt, N., Cleeren, F., Bormans, G., Broisat, A., Caveliers, V., Xavier, C., Vanhove, C. & Hernot, S., 1 apr 2020, In : Molecules. 25, 8, 25081838.Onderzoeksoutput: Article
3 Citaten (Scopus)
Prijzen
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ESMI presentation award for best oral presentation
Jessica Bridoux (Recipient), Katrijn Broos (Recipient), Quentin Lecocq (Recipient), Maxine Crauwels (Recipient), Charlotte Martin (Recipient), Frederik Cleeren (Recipient), Mikhail Kondrashov (Recipient), Steven Ballet (Recipient), G. Bormans (Recipient), Magnus Schou (Recipient), Chad Elmore (Recipient), Geert Raes (Recipient), Karine Breckpot (Recipient), Serge Muyldermans (Recipient), Nick Devoogdt (Recipient), Marleen Keyaerts (Recipient), Vicky Caveliers (Recipient) & Catarina Xavier (Recipient), 17 jan 2020
Prijs: Prize (including medals and awards)
Activiteiten
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2020-74
Tony Lahoutte (Supervisor), Vicky Caveliers (Contributor), Catarina Xavier (Contributor), Jessica Bridoux (Contributor), Herlinde Dierick (Contributor)2020Activiteit: Other
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Immuno-PET imaging using the hPD-L1 Nanobody: Radiolabelling strategies
Jessica Bridoux (Speaker), Katrijn Broos (Contributor), Quentin Lecocq (Contributor), Maxine Crauwels (Contributor), Charlotte Martin (Contributor), Frederik Cleeren (Contributor), Mikhail Krivoshapov (Speaker), Steven Ballet (Speaker), G. Bormans (Speaker), Geert Raes (Speaker), Karine Breckpot (Speaker), Serge Muyldermans (Speaker), Magnus Schou (Speaker), Chad Elmore (Speaker), Nick Devoogdt (Speaker), Vicky Caveliers (Speaker), Marleen Keyaerts (Speaker), Catarina Xavier (Speaker)14 jan 2020Activiteit: Talk or presentation at a conference
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Radiofarmacie
Vicky Caveliers (Speaker)2 mrt 2019Activiteit: Talk or presentation at a workshop/seminar
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2019-68
Vicky Caveliers (Supervisor), Matthias D'Huyvetter (Contributor), Laurent Navarro (Contributor)2019Activiteit: Other
Knipsels
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Ontwikkeling van nanobodies voor de visualisatie van tumoren.
11/12/17
1 Mediabijdrage
Pers / media: !!Research
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Kikkers gebruiken moleculen als micro-giftanden om roofdieren te vergiftigen
Kim Roelants, Vicky Caveliers, Sophie Hernot & Cindy Peleman
16/11/17
1 Mediabijdrage
Pers / media: !!Research
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Tackling a shortage of PET scientists and improving healthcare
Jessica Bridoux, Vicky Caveliers & Catarina Xavier
1/10/17
1 Mediabijdrage
Pers / media: !!Research
Scriptie
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Amino acids in oncology diagnostics: Development of new PET probes targeting the glutamine transporter ASCT-2
Auteur: Baguet, T., De Vos, F., Van Calenbergh, S. & Caveliers, V., 3 jul 2020Scriptie/masterproef: Doctoral Thesis
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A multistep manufacturing protocol for the site-specific radiolabeling of a nanobody with [18F]Al.
Auteur: Vanmarcke, S. G., Caveliers, V. & Bridoux, J., 13 jun 2018Scriptie/masterproef: Master's Thesis
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Analysis of glutamate transporter expression in post mortem tissue of depressed patients
Auteur: Rubbens, N., Demuyser, T., Massie, A., Smolders, I. & Caveliers, V., 2016Begeleider: Demuyser, T. (Promotor)
Scriptie/masterproef: Master's Thesis
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Bepaling van de plasmastabiliteit van een synthetisch peptide en preliminair onderzoek naar het minimaliseren van peptide-adsorptie tijdens microdialyse
Auteur: Van den Borre, L., Van Eeckhaut, A., Caveliers, V. & Doktorova, T., 10 jun 2015Scriptie/masterproef: Master's Thesis
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Bepaling van de specifieke activiteit van cyclotron geproduceerd F18-fluoride en F18-gemerkt radiofarmacon
Auteur: Deprez, M., Caveliers, V., Blykers, A., De Kock, J. & Vander Heyden, Y., 10 jun 2015Scriptie/masterproef: Master's Thesis