Projecten per jaar
Persoonlijk profiel
Expertise
Development of radiopharmaceuticals for PET and radionuclide therapy applications based on camelid single domain antibody fragments (also called VHH or Nanobodies).
Optimization of (automated) radiolabeling procedures, purification methods and formulation. In vitro and in vivo evaluation of new radiopharmaceutical probes in terms of biodistribution, in vivo stability and targeting potential. Translation of preclinically validated tracers to early phase clinical trials, including fulfilling all regulatory requirements.
GMP manufacturing of radiopharmaceuticals.
Vingerafdruk
Verdiep u in de onderzoeksgebieden waarop Vicky Caveliers actief is. Deze onderwerplabels komen uit het werk van deze persoon. Samen vormen ze een unieke vingerafdruk.
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
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OZR4288: Financiering MZW OZR: Snelle analyse en productie van eiwitten voor klinische translatie met behulp van Biacore en bioreactor systemen.
Devoogdt, N., Hernot, S., De Groof, T., Ballet, S., Stijlemans, B., Massie, A., Rooman, I., Keyaerts, M., Raes, G., De Kock, J., Breckpot, K., De Veirman, K. & Caveliers, V.
24/04/24 → 24/04/28
Project: Fundamenteel
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SRP95: Exploitatie van Peptiden als Proteïne Binders, Modulatoren, Inhibitoren en Biomaterialen voor Beeldvorming en Therapie
Ballet, S., Caveliers, V., Hernot, S., Versées, W., Devoogdt, N., Covens, P. & Martin, C.
1/03/24 → 28/02/29
Project: Fundamenteel
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FWOIRI10: Onderzoek op radioactieve kernen aan ISOLDE-CERN, SPIRAL2-GANIL and MEDICIS-CERN
Caveliers, V. & D'Huyvetter, M.
1/01/23 → 31/12/26
Project: Fundamenteel
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HERC59: PET camera voor beeldvorming van kleine proefdieren
Devoogdt, N., Raes, G., Lahoutte, T., Van Ginderachter, J., Caveliers, V., Keyaerts, M., Hernot, S. & D'Huyvetter, M.
1/05/22 → 30/04/26
Project: Fundamenteel
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FWOSB114: Ontwikkeling van een nieuwe chemo-enzymatische strategie voor de generatie van radioactief fluor-gemerkte PET-probes
Declercq, S., Devoogdt, N., Bridoux, J. & Caveliers, V.
1/11/21 → 31/10/26
Project: Fundamenteel
Onderzoeksoutput
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Generic semi-automated radiofluorination strategy for single domain antibodies: [18F]FB-labelled single domain antibodies for PET imaging of fibroblast activation protein-α or folate receptor-α overexpression in cancer
Dierick, H., Navarro, L., Ceuppens, H., Ertveldt, T., Pombo Antunes, A. R., Keyaerts, M., Devoogdt, N., Breckpot, K., D'Huyvetter, M., Lahoutte, T., Caveliers, V. & Bridoux, J., dec 2024, In: EJNMMI Radiopharmacy and Chemistry. 9, 1, 14 blz., 54.Onderzoeksoutput: Article › peer review
Open AccessBestand1 Citaat (Scopus) -
In-hospital production and quality control of radiotracer [68Ga]Ga-NODAGA-Exendin-4 on Trasis EasyOne synthesizer
Van den Block, S., Caveliers, V., Bourgeois, S., Masset, J. & Vriamont, C., 2024, (Unpublished).Onderzoeksoutput: Poster
Bestand47 Downloads (Pure) -
Phase II Trial Assessing the Repeatability and Tumor Uptake of [68Ga]Ga-HER2 Single-Domain Antibody PET/CT in Patients with Breast Carcinoma
Gondry, O., Caveliers, V., Xavier, C., Vanhoeij, M., Verfaillie, G., Fontaine, C., Glorieus, K., De Grève, J., Joris, S., Luyten, I., Zwaenepoel, K., Vandenbroucke, F., Waelput, W., Thyparambil, S., Vaneycken, I., Cousaert, J., Bourgeois, S., Devoogdt, N., Goethals, L., Everaert, H. & 4 anderen, , 1 feb 2024, In: Journal of Nuclear Medicine. 65, 2, blz. 178-184 7 blz.Onderzoeksoutput: Article › peer review
Open AccessBestand9 Citaten (Scopus)43 Downloads (Pure) -
Sustained release of a human pd-l1 single-domain antibody using peptide-based hydrogels
Heremans, J., Maximilian Awad, R., Bridoux, J., Ertveldt, T., Caveliers, V., Madder, A., Hoogenboom, R., Devoogdt, N., Ballet, S., Hernot, S., Breckpot, K. & Martin, C., mrt 2024, In: European Journal of Pharmaceutics and Biopharmaceutics. 196, 196, 21 blz., 114183.Onderzoeksoutput: Article › peer review
Open AccessBestand103 Downloads (Pure) -
A comparison of [68Ga]Ga-NOTA-anti-HER2-sdAb PET/CT with [18F]FDG-PET/CT in breast carcinoma patients.
Gondry, O., Xavier, C., Heemskerk, J., Raes, L. A. J., Debacker, J., De Geeter, F., Fontaine, C., Vanhoeij, M., Aspeslagh, S., Joris, S., De Grève, J., Verfaillie, G., Luyten, I., De Mey, L., Vandenbroucke, F., Waelput, W., Glorieus, K., Bourgeois, S., Cousaert, J., Vaneycken, I. & 5 anderen, , 2023.Onderzoeksoutput: Unpublished abstract
Prijzen
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ESMI presentation award for best oral presentation
Bridoux, Jessica (Recipient), Broos, K. (Recipient), Lecocq, Q. (Recipient), Crauwels, M. (Recipient), Martin, Charlotte (Recipient), Cleeren, F. (Recipient), Kondrashov, M. (Recipient), Ballet, Steven (Recipient), Bormans, G. (Recipient), Schou, M. (Recipient), Elmore, C. (Recipient), Raes, Geert (Recipient), Breckpot, Karine (Recipient), Muyldermans, Serge (Recipient), Devoogdt, Nick (Recipient), Keyaerts, Marleen (Recipient), Caveliers, Vicky (Recipient) & Xavier, C. (Recipient), 17 jan 2020
Prijs: Prize (including medals and awards)
Activiteiten
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PET/CT imaging of high mannose receptor expressing macrophages: first clinical results in cancer and inflammatory disease
Lynn De Mey (Speaker), Odrade Gondry (Contributor), Amelientje Bracke (Contributor), Sophie Bourgeois (Contributor), Hendrik Everaert (Contributor), Lode Goethals (Contributor), Laurens Raes (Contributor), Juanito Gebruers (Contributor), Wim Waelput (Contributor), Vicky Caveliers (Contributor), Jens Debacker (Contributor), Nick Devoogdt (Contributor), Herlinde Dierick (Contributor), Julie Cousaert (Contributor), Nathan De Beule (Contributor), Laura Anna A Kerselaers (Contributor), Marleen Keyaerts (Contributor) & Tony Lahoutte (Contributor)
3 dec 2024Activiteit: Talk or presentation at a conference
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Fully automated production of [18F]FB-labeled single-domain antibodies: the immune-checkpoint TIGIT for PET imaging
Herlinde Dierick (Speaker), Katty Zeven (Contributor), Laurent Navarro (Contributor), Tony Lahoutte (Contributor), Nick Devoogdt (Contributor), Vicky Caveliers (Contributor) & Jessica Bridoux (Contributor)
18 apr 2024 → 21 apr 2024Activiteit: Talk or presentation at a conference
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The future Radiopharmacy: challenge and/or opportunity?
Vicky Caveliers (Speaker)
22 apr 2023Activiteit: Talk or presentation at a conference
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EXPLORING THE POTENTIAL OF [18F]ALF-PSMA-11 FOR PROSTATE CANCER IMAGING (Evenement)
Sarah Piron (Presenter) & Vicky Caveliers (Jury)
13 jan 2023Activiteit: Member of PhD committee
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Site-specifically THP-functionalized hPD-L1 single domain antibody; preliminary data toward kit development
Herlinde Dierick (Speaker), Henri Vincent Baudhuin (Contributor), Vicky Caveliers (Contributor) & Jessica Bridoux (Contributor)
26 mei 2023Activiteit: Talk or presentation at a conference
Knipsels
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Ontwikkeling van nanobodies voor de visualisatie van tumoren.
11/12/17
1 Mediabijdrage
Pers / media: !!Research
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Kikkers gebruiken moleculen als micro-giftanden om roofdieren te vergiftigen
Kim Roelants, Vicky Caveliers, Sophie Hernot & Cindy Peleman
16/11/17
1 Mediabijdrage
Pers / media: !!Research
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Tackling a shortage of PET scientists and improving healthcare
Jessica Bridoux, Vicky Caveliers & Catarina Xavier
1/10/17
1 Mediabijdrage
Pers / media: !!Research
Scriptie
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Amino acids in oncology diagnostics: Development of new PET probes targeting the glutamine transporter ASCT-2
Auteur: Baguet, T., De Vos, F., Van Calenbergh, S. & Caveliers, V., 3 jul 2020Scriptie/Masterproef: Doctoral Thesis
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A multistep manufacturing protocol for the site-specific radiolabeling of a nanobody with [18F]Al.
Auteur: Vanmarcke, S. G., Caveliers, V. & Bridoux, J., 13 jun 2018Scriptie/Masterproef: Master's Thesis
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Analysis of glutamate transporter expression in post mortem tissue of depressed patients
Auteur: Rubbens, N., Demuyser, T., Massie, A., Smolders, I. & Caveliers, V., 2016Begeleider: Demuyser, T. (Promotor)
Scriptie/Masterproef: Master's Thesis
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Analytical method validation of radiopharmaceutical [18F]PSMA-7 in a GMP environment
Auteur: ten Haaf, M. & Caveliers, V., 17 jun 2022Scriptie/Masterproef: Master's Thesis
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Bepaling van de plasmastabiliteit van een synthetisch peptide en preliminair onderzoek naar het minimaliseren van peptide-adsorptie tijdens microdialyse
Auteur: Van den Borre, L., Van Eeckhaut, A., Caveliers, V. & Doktorova, T., 10 jun 2015Scriptie/Masterproef: Master's Thesis