Projecten per jaar
Persoonlijk profiel
Expertise
Development of radiopharmaceuticals for PET and radionuclide therapy applications based on camelid single domain antibody fragments (also called VHH or Nanobodies).
Optimization of (automated) radiolabeling procedures, purification methods and formulation. In vitro and in vivo evaluation of new radiopharmaceutical probes in terms of biodistribution, in vivo stability and targeting potential. Translation of preclinically validated tracers to early phase clinical trials, including fulfilling all regulatory requirements.
GMP manufacturing of radiopharmaceuticals.
Vingerafdruk
Verdiep u in de onderzoeksgebieden waarop Vicky Caveliers actief is. Deze onderwerplabels komen uit het werk van deze persoon. Samen vormen ze een unieke vingerafdruk.
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
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FWOAL1154: VYPER — Viola Yedoensis Peptide asparagine ligase (VyPAL) Enzyme-gemedieerde ontwikkeling van Radiotheranostica
Devoogdt, N., Caveliers, V. & Bridoux, J.
1/01/25 → 31/12/28
Project: Fundamenteel
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OZR4288: Financiering MZW OZR: Snelle analyse en productie van eiwitten voor klinische translatie met behulp van Biacore en bioreactor systemen.
Devoogdt, N., Hernot, S., De Groof, T., Ballet, S., Stijlemans, B., Massie, A., Rooman, I., Keyaerts, M., Raes, G., De Kock, J., Breckpot, K., De Veirman, K. & Caveliers, V.
24/04/24 → 24/04/28
Project: Fundamenteel
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SRP95: Exploitatie van Peptiden als Proteïne Binders, Modulatoren, Inhibitoren en Biomaterialen voor Beeldvorming en Therapie
Ballet, S., Caveliers, V., Hernot, S., Versées, W., Devoogdt, N., Covens, P. & Martin, C.
1/03/24 → 28/02/29
Project: Fundamenteel
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FWOIRI10: Onderzoek op radioactieve kernen aan ISOLDE-CERN, SPIRAL2-GANIL and MEDICIS-CERN
Caveliers, V. & D'Huyvetter, M.
1/01/23 → 31/12/26
Project: Fundamenteel
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HERC59: PET camera voor beeldvorming van kleine proefdieren
Devoogdt, N., Raes, G., Lahoutte, T., Van Ginderachter, J., Caveliers, V., Keyaerts, M., Hernot, S. & D'Huyvetter, M.
1/05/22 → 30/04/26
Project: Fundamenteel
Onderzoeksoutput
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VyPAL2 peptide asparaginyl ligase enables versatile workflows for radiolabeling single-domain antibody-based theranostics
Declercq, S., Chen, W. M., EL SAHILI, ABBAS., Lamouroux, A., Gonzales, I., Martin, C., Ballet, S., Caveliers, V., Devoogdt, N., Lescar, J. & Bridoux, J., 10 dec. 2025, In: Journal of Controlled Release. 388, 17 blz., 114361.Onderzoeksoutput: Article › peer review
Open Access -
[68Ga]Ga-NOTA-anti-HER2-VHH1PET/CT Imaging of brain metastasis: first clinical results in patients with HER2 positive and HER2 negative breast cancer.
De Mey, L., Gondry, O. (redactie), Bourgeois, S. (redactie), Bracke, A. (redactie), Everaert, H. (redactie), Goethals, L. (redactie), Raes, L. (redactie), Caveliers, V. (redactie), Van den Block, S. (redactie), Decoster, L. (redactie), Fontaine, C. (redactie), Devoogdt, N. (redactie), Dierick, H. (redactie), Cousaert, J. (redactie), Lahoutte, T. (redactie) & Keyaerts, M. (redactie), 2024.Onderzoeksoutput: Poster
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Automated radiofluorination of HER2 single domain antibody: the road towards the clinical translation of [18F]FB-HER2 sdAb
Dierick, H., Navarro, L., Van den Block, S., Saliën, J., Lahoutte, T., Caveliers, V. & Bridoux, J., 14 nov. 2024, In: EJNMMI Radiopharmacy and Chemistry. 9, 1, 77 blz., 77.Onderzoeksoutput: Article › peer review
Open AccessBestand7 Downloads (Pure) -
Generic semi-automated radiofluorination strategy for single domain antibodies: [18F]FB-labelled single domain antibodies for PET imaging of fibroblast activation protein-α or folate receptor-α overexpression in cancer
Dierick, H., Navarro, L., Ceuppens, H., Ertveldt, T., Pombo Antunes, A. R., Keyaerts, M., Devoogdt, N., Breckpot, K., D'Huyvetter, M., Lahoutte, T., Caveliers, V. & Bridoux, J., dec. 2024, In: EJNMMI Radiopharmacy and Chemistry. 9, 1, 14 blz., 54.Onderzoeksoutput: Article › peer review
Open AccessBestand8 Citaten (Scopus)54 Downloads (Pure) -
In-hospital production and quality control of radiotracer [68Ga]Ga-NODAGA-Exendin-4 on Trasis EasyOne synthesizer
Van den Block, S., Masset, J., Vriamont, C., Bourgeois, S. & Caveliers, V., 2024, (Unpublished).Onderzoeksoutput: Poster
Bestand72 Downloads (Pure)
Prijzen
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ESMI presentation award for best oral presentation
Bridoux, Jessica (Recipient), Broos, Katrijn (Recipient), Lecocq, Quentin (Recipient), Crauwels, Maxine (Recipient), Martin, Charlotte (Recipient), Cleeren, Frederik (Recipient), Kondrashov, Mikhail (Recipient), Ballet, Steven (Recipient), Bormans, G. (Recipient), Schou, Magnus (Recipient), Elmore, Chad (Recipient), Raes, Geert (Recipient), Breckpot, Karine (Recipient), Muyldermans, Serge (Recipient), Devoogdt, Nick (Recipient), Keyaerts, Marleen (Recipient), Caveliers, Vicky (Recipient) & Xavier, Catarina (Recipient), 17 jan. 2020
Prijs: Prize (including medals and awards)
Activiteiten
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Enzyme-mediated site-specific functionalization in nuclear medicine: indirect strategies to generate single-domain antibody-based radiopharmaceuticals using the VyPAL2 asparaginyl peptide ligase.
Sofie Declercq (Contributor), Wei Min Chen (Contributor), ABBAS EL SAHILI (Contributor), Arthur Lamouroux (Contributor), Ilyana Gonzales (Contributor), Steven Ballet (Contributor), Vicky Caveliers (Contributor), Nick Devoogdt (Contributor), Julien Lescar (Contributor) & Jessica Bridoux (Speaker)
14 mei 2025Activiteit: Talk or presentation at a conference
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Fully automated production of [18F]FB-labeled single-domain antibodies: the immune-checkpoint TIGIT for PET imaging
Herlinde Dierick (Speaker), Katty Zeven (Contributor), Laurent Navarro (Contributor), Tony Lahoutte (Contributor), Nick Devoogdt (Contributor), Vicky Caveliers (Contributor) & Jessica Bridoux (Contributor)
18 apr. 2024 → 21 apr. 2024Activiteit: Talk or presentation at a conference
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PET/CT imaging with [68Ga]Ga-NOTA-anti-HER2-VHH1 in cancer patients with potential HER2 expression: first clinical results.
Lynn De Mey (Speaker), Odrade Gondry (Contributor), Sophie Bourgeois (Contributor), Amelientje Bracke (Contributor), Hendrik Everaert (Contributor), Lode Goethals (Contributor), Laurens Raes (Contributor), Vicky Caveliers (Contributor), Sonja Van den Block (Contributor), Sofie Joris (Contributor), Amy de Haar-Holleman (Contributor), Christel Fontaine (Contributor), Nick Devoogdt (Contributor), Herlinde Dierick (Contributor), Julie Cousaert (Contributor), Tony Lahoutte (Contributor) & Marleen Keyaerts (Contributor)
22 okt. 2024Activiteit: Talk or presentation at a conference
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PET/CT imaging with [68Ga]Ga-NOTA-anti-MMR-VHH2 in patients with NSCLC: Interim results of the MAGMA trial
Lynn De Mey (Speaker), Sophie Bourgeois (Contributor), Amelientje Bracke (Contributor), Hendrik Everaert (Contributor), Lode Goethals (Contributor), Odrade Gondry (Contributor), Jens Debacker (Contributor), Marleen Keyaerts (Contributor), Nick Devoogdt (Contributor), Ramses Forsyth (Contributor), Hanne Locy (Contributor), Laurens Raes (Contributor), Vicky Caveliers (Contributor), Sonja Van den Block (Contributor), Ilse Vaneycken (Contributor), Julie Cousaert (Contributor) & Tony Lahoutte (Contributor)
11 okt. 2024Activiteit: Talk or presentation at a conference
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PET/CT imaging of high mannose receptor expressing macrophages with [68Ga]Ga-NOTA -Anti-MMR-VHH2: an overview of the clinical results
Lynn De Mey (Speaker), Sophie Bourgeois (Contributor), Amelientje Bracke (Contributor), Odrade Gondry (Contributor), Hendrik Everaert (Contributor), Lode Goethals (Contributor), Jens Debacker (Contributor), Marleen Keyaerts (Contributor), Nick Devoogdt (Contributor), Laurens Raes (Contributor), Vicky Caveliers (Contributor), Sonja Van den Block (Contributor), Ilse Vaneycken (Contributor), Julie Cousaert (Contributor), Nathan De Beule (Contributor), Laura Anna A Kerselaers (Contributor), Ramses Forsyth (Contributor), Hanne Locy (Contributor) & Tony Lahoutte (Contributor)
11 okt. 2024Activiteit: Talk or presentation at a conference
Knipsels
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Ontwikkeling van nanobodies voor de visualisatie van tumoren.
11/12/17
1 Mediabijdrage
Pers / media: !!Research
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Kikkers gebruiken moleculen als micro-giftanden om roofdieren te vergiftigen
Kim Roelants, Vicky Caveliers, Sophie Hernot & Cindy Peleman
16/11/17
1 Mediabijdrage
Pers / media: !!Research
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Tackling a shortage of PET scientists and improving healthcare
Jessica Bridoux, Vicky Caveliers & Catarina Xavier
1/10/17
1 Mediabijdrage
Pers / media: !!Research
Scriptie
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Amino acids in oncology diagnostics: Development of new PET probes targeting the glutamine transporter ASCT-2
Auteur: Baguet, T., De Vos, F., Van Calenbergh, S. & Caveliers, V., 3 jul. 2020Scriptie/Masterproef: Doctoral Thesis
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A multistep manufacturing protocol for the site-specific radiolabeling of a nanobody with [18F]Al.
Auteur: Vanmarcke, S. G., Caveliers, V. & Bridoux, J., 13 jun. 2018Scriptie/Masterproef: Master's Thesis
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Analysis of glutamate transporter expression in post mortem tissue of depressed patients
Auteur: Rubbens, N., Demuyser, T., Massie, A., Smolders, I. & Caveliers, V., 2016Begeleider: Demuyser, T. (Promotor)
Scriptie/Masterproef: Master's Thesis
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Analytical method validation of radiopharmaceutical [18F]PSMA-7 in a GMP environment
Auteur: ten Haaf, M. & Caveliers, V., 17 jun. 2022Scriptie/Masterproef: Master's Thesis
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Bepaling van de plasmastabiliteit van een synthetisch peptide en preliminair onderzoek naar het minimaliseren van peptide-adsorptie tijdens microdialyse
Auteur: Van den Borre, L., Van Eeckhaut, A., Caveliers, V. & Doktorova, T., 10 jun. 2015Scriptie/Masterproef: Master's Thesis