Combineren van gerichte radionuclide therapie en kanker immuun therapie om precisie geneeskunde te bevorderen door innovatie.

Breckpot, Karine (Administrative Promotor)
Devoogdt, Nick (Co-Promoter)
D'Huyvetter, Matthias (Co-Promoter)
Keyaerts, Marleen (Co-Promoter)
Ertveldt, Thomas (Mandataris)

4 Poster
4 Article
2 Patent
1 PhD Thesis

4 resultaten

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2023
Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine
Ertveldt, T., Meulewaeter, S., De Vlaeminck, Y., Olarte, O., Broos, K., Van Calenbergh, S., Bourgeois, S., Deprez, J., Heremans, Y., Goyvaerts, C., Staels, W., De Smedt, S., Dewitte, H., Devoogdt, N., Keyaerts, M., Verbeke, R., Barbé, K., Lentacker, I. & Breckpot, K., 9 okt. 2023, In: Theranostics. 13, 15, blz. 5483-5500 18 blz.
Onderzoeksoutput: Article › peer review

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11 Citaten (Scopus)

80 Downloads (Pure)
Targeted α-Therapy Using 225Ac Radiolabeled Single-Domain Antibodies Induces Antigen-Specific Immune Responses and Instills Immunomodulation Both Systemically and at the Tumor Microenvironment
Ertveldt, T., Krasniqi, A., Ceuppens, H., Puttemans, J., Dekempeneer, Y., De Jonghe, K., de Mey, W., Lecocq, Q., De Vlaeminck, Y., Awad, R. M., Goyvaerts, C., De Veirman, K., Morgenstern, A., Bruchertseifer, F., Keyaerts, M., Devoogdt, N., D'Huyvetter, M. & Breckpot, K., 1 mei 2023, In: Journal of Nuclear Medicine. 64, 5, blz. 751-758 8 blz.
Onderzoeksoutput: Article › peer review

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25 Citaten (Scopus)

177 Downloads (Pure)
2022
Targeted radionuclide therapy with low and high-dose Lutetium-177 labeled single domain antibodies induces distinct immune signatures in a mouse melanoma model
Ertveldt, T., De Beck, L., De Ridder, K., Locy, H., De Mey, W., Goyvaerts, C., Lecocq, Q., Ceuppens, H., De Vlaeminck, Y., Awad, R. M., Keyaerts, M., Devoogdt, N., D'Huyvetter, M., Breckpot, K. & Krasniqi, A., jul. 2022, In: Molecular Cancer Therapeutics. 21, 7, blz. 1136-1148 13 blz.
Onderzoeksoutput: Article › peer review

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16 Citaten (Scopus)

131 Downloads (Pure)
2021
CS1-specific single-domain antibodies labeled with Actinium-225 prolong survival and increase CD8+ T cells and PD-L1 expression in Multiple Myeloma
De Veirman, K., Puttemans, J., Krasniqi, A., Ertveldt, T., Hanssens, H., Romao, E., Hose, D., Goyvaert, C., Vlummens, P., Muyldermans, S., Breckpot, K., Bruchertseifer, F., Morgenstern, A., D'Huyvetter, M. & Devoogdt, N., 2021, In: Oncoimmunology. 10, 1, 11 blz., 2000699.
Onderzoeksoutput: Article › peer review

Open Access
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19 Citaten (Scopus)

82 Downloads (Pure)