A novel method of luteal supplementation with recombinant luteinizing hormone when a gonadotropin-releasing hormone agonist is used instead of human chorionic gonadotropin for ovulation triggering: a randomized prospective proof of concept study.

Evangelos Papanikolaou; Willem Verpoest; Mousavi Fatemi; Basil Tarlatzis; Paul Devroey; Herman Tournaye

A novel method of luteal supplementation with recombinant luteinizing hormone when a gonadotropin-releasing hormone agonist is used instead of human chorionic gonadotropin for ovulation triggering: a randomized prospective proof of concept study.

Evangelos Papanikolaou, Willem Verpoest, Mousavi Fatemi, Basil Tarlatzis, Paul Devroey, Herman Tournaye

Onderzoeksoutput: Article › peer review

104 Citaten (Scopus)

Samenvatting

This pilot study investigates the role of luteal supplementation with recombinant LH in an attempt to reverse the poor reproductive outcome previously noticed after GnRH-agonist triggering of final oocyte maturation for IVF. Similar implantation rates were achieved with the novel recombinant LH luteal supplementation scheme compared with the standard luteal P protocol (25.0% vs. 26.7%, respectively). No cases of ovarian hyperstimulation syndrome (OHSS) were noticed in either group.

Originele taal-2	English
Pagina's (van-tot)	1174-1177
Tijdschrift	Fertility and Sterility
Volume	95
Nummer van het tijdschrift	3
Status	Published - mrt 2011

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Citeer dit

Papanikolaou, E., Verpoest, W., Fatemi, M., Tarlatzis, B., Devroey, P., & Tournaye, H. (2011). A novel method of luteal supplementation with recombinant luteinizing hormone when a gonadotropin-releasing hormone agonist is used instead of human chorionic gonadotropin for ovulation triggering: a randomized prospective proof of concept study. Fertility and Sterility, 95(3), 1174-1177.

Papanikolaou, Evangelos ; Verpoest, Willem ; Fatemi, Mousavi ; Tarlatzis, Basil ; Devroey, Paul ; Tournaye, Herman. / A novel method of luteal supplementation with recombinant luteinizing hormone when a gonadotropin-releasing hormone agonist is used instead of human chorionic gonadotropin for ovulation triggering: a randomized prospective proof of concept study. In: Fertility and Sterility. 2011 ; Vol. 95, Nr. 3. blz. 1174-1177.

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abstract = "This pilot study investigates the role of luteal supplementation with recombinant LH in an attempt to reverse the poor reproductive outcome previously noticed after GnRH-agonist triggering of final oocyte maturation for IVF. Similar implantation rates were achieved with the novel recombinant LH luteal supplementation scheme compared with the standard luteal P protocol (25.0% vs. 26.7%, respectively). No cases of ovarian hyperstimulation syndrome (OHSS) were noticed in either group.",

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Papanikolaou, E, Verpoest, W, Fatemi, M, Tarlatzis, B, Devroey, P & Tournaye, H 2011, 'A novel method of luteal supplementation with recombinant luteinizing hormone when a gonadotropin-releasing hormone agonist is used instead of human chorionic gonadotropin for ovulation triggering: a randomized prospective proof of concept study.', Fertility and Sterility, vol. 95, nr. 3, blz. 1174-1177.

A novel method of luteal supplementation with recombinant luteinizing hormone when a gonadotropin-releasing hormone agonist is used instead of human chorionic gonadotropin for ovulation triggering: a randomized prospective proof of concept study. / Papanikolaou, Evangelos; Verpoest, Willem; Fatemi, Mousavi; Tarlatzis, Basil; Devroey, Paul ; Tournaye, Herman.

In: Fertility and Sterility, Vol. 95, Nr. 3, 03.2011, blz. 1174-1177.

Onderzoeksoutput: Article › peer review

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AU - Papanikolaou, Evangelos

AU - Verpoest, Willem

AU - Fatemi, Mousavi

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AU - Devroey, Paul

AU - Tournaye, Herman

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AB - This pilot study investigates the role of luteal supplementation with recombinant LH in an attempt to reverse the poor reproductive outcome previously noticed after GnRH-agonist triggering of final oocyte maturation for IVF. Similar implantation rates were achieved with the novel recombinant LH luteal supplementation scheme compared with the standard luteal P protocol (25.0% vs. 26.7%, respectively). No cases of ovarian hyperstimulation syndrome (OHSS) were noticed in either group.

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KW - agonist triggering

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KW - GnRH-antagonist

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Papanikolaou E, Verpoest W, Fatemi M, Tarlatzis B, Devroey P , Tournaye H. A novel method of luteal supplementation with recombinant luteinizing hormone when a gonadotropin-releasing hormone agonist is used instead of human chorionic gonadotropin for ovulation triggering: a randomized prospective proof of concept study. Fertility and Sterility. 2011 mrt;95(3):1174-1177.