A retrospective analysis: follow up with 18F-fluoro-2-deoxy-d-glucose-positron emission tomography/computed tomography in oro- and hypopharyngeal squamous cell carcinoma patients

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Samenvatting

Objective
This study evaluated the significance of positron emission tomography/computed tomography (PET/CT) in detecting recurrences or other primary malignancies in patients treated for oro- and hypopharyngeal squamous cell carcinoma.

Method
A retrospective analysis of the follow up of 132 patients was performed and 370 PET/CT scans were assessed for their accuracy.

Results
All asymptomatic clinical occult recurrences were detected by PET/CT and accounted for 28 per cent of recurrences. Asymptomatic patients with metastases detected by PET/CT had a significant survival benefit compared to patients diagnosed in a symptomatic stage. For locoregional recurrence, no significant difference in overall survival could be demonstrated. In total, 33 primary malignancies were discovered, of which 48 per cent were first detected by PET/CT. The specificity and negative predictive value of the PET/CT scans had ranges of 85–100 and 83–100 per cent, respectively.

Conclusion
The role of PET/CT scans in detecting primary malignancies, clinical occult recurrences and especially asymptomatic metastases was observed.
Originele taal-2English
Aantal pagina's8
TijdschriftThe Journal of Laryngology and Otology
Volume138
Nummer van het tijdschriftS2
DOI's
StatusPublished - 2023

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