@article{8a8ce4f308bf481ca86c8cf3ce04b386,
title = "A role for leptin in the systemic inflammatory response syndrome (SIRS) and in immune response, an update.",
abstract = "Leptin was originally identified as an adipocyte-derived cytokine with a key role in the regulation of the energy balance. Subsequent research revealed that leptin's biological action is not restricted to its effects on appetite and food intake, but instead has a much more pleiotropic character. There is now ample evidence that leptin has important functions in reproduction, hematopoiesis, HPA-axis endocrinology and angiogenesis. In this review we have focused on the effects of leptin in the antigen-specific immunity and in the inflammatory effector system.",
keywords = "Adaptation, Physiological, Animals, Anorexia, Anorexia: physiopathology, Humans, Immunity, Immunity: physiology, Inflammation, Inflammation: physiopathology, Leptin, Leptin: physiology, Macrophages, Macrophages: drug effects, Macrophages: physiology, Metallothionein, Metallothionein: biosynthesis, Monocytes, Monocytes: drug effects, Monocytes: physiology, Receptors, Cell Surface, Receptors, Cell Surface: physiology, Receptors, Leptin, Starvation, Starvation: physiopathology, Systemic Inflammatory Response Syndrome, Systemic Inflammatory Response Syndrome: physiopat, T-Lymphocytes, T-Lymphocytes: physiology, alpha-MSH, alpha-MSH: physiology",
author = "W Waelput and P Brouckaert and D Broekaert and J Tavernier",
year = "2006",
month = jan,
language = "English",
volume = "13",
pages = "465--475",
journal = "Current Medicinal Chemistry",
issn = "0929-8673",
publisher = "Bentham Science Publishers",
number = "4",
}