Advances in ultra‐high‐pressure and multi‐dimensional liquid chromatography instrumentation and workflows

Jelle De Vos, Dwight Stoll, Stephan Buckenmaier, Sebastiaan Eeltink, James Grinias

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Samenvatting

The present contribution discusses recent advances in ultra‐high‐pressure liquid chromatography (UHPLC) and multi‐dimensional liquid chromatography (MDLC) technology. First, new developments in UHPLC column technology and system design are highlighted. The latter includes a description of a novel injector concept enabling method speed‐up, emerging detectors, and instrument diagnostics approaches. Next, online MDLC workflows are reviewed and advances in modulation technology are highlighted. Finally, key applications published in 2020 are reviewed.
Originele taal-2English
Pagina's (van-tot)171-192
Aantal pagina's22
TijdschriftAnalytical Science Advances
Volume2
Nummer van het tijdschrift3-4
Vroegere onlinedatum16 mrt 2021
DOI's
StatusPublished - 9 apr 2021

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