An unexpected complication of chronic myelomonocytic leukemia: severe renal failure due to malignant tubulo-interstitial cell infiltration

Jerrold Spapen, Karel Fostier, Hendrik De Raeve, Peter Janssens, Herbert Spapen

Onderzoeksoutput: Articlepeer review

Samenvatting

Acute renal failure may complicate the course of a hematologic malignancy but is a highly unusual finding in patients with chronic myelomonocytic leukemia. Kidney biopsy is rarely performed in this setting, and the pathologic substrate underlying kidney injury is not well identified. We present a case of a biopsy-proven acute tubulo-interstitial nephritis due to massive infiltration of neoplastic myelomonocytic cells. Since the leukemic process involving the kidney may respond favorably to treatment, a renal biopsy should be considered in any patient presenting with unexplained severe or evolving kidney disease.

Originele taal-2English
Pagina's (van-tot)1-4
Aantal pagina's4
TijdschriftInternational Journal of Nephrology and Renovascular Disease
Volume9
DOI's
StatusPublished - 2016

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