TY - JOUR
T1 - Assessment of filling pressures and fluid overload in heart failure
T2 - an updated perspective
AU - Espriella, Rafael De La
AU - Cobo, Marta
AU - Santas, Enrique
AU - Verbrugge, Frederik H
AU - Fudim, Marat
AU - Girerd, Nicolas
AU - Miñana, Gema
AU - Luis Górriz, José
AU - Bayés-Genís, Antoni
AU - Núñez, Julio
N1 - Copyright © 2022 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.
PY - 2023/1
Y1 - 2023/1
N2 - Congestion plays a major role in the pathogenesis, presentation, and prognosis of heart failure and is an important therapeutic target. However, its severity and organ and compartment distribution vary widely among patients, illustrating the complexity of this phenomenon. Although clinical symptoms and signs are useful to assess congestion and manage volume status in individual patients, they have limited sensitivity and do not allow identification of congestion phenotype. This leads to diagnostic uncertainty and hampers therapeutic decision-making. The present article provides an updated overview of circulating biomarkers, imaging modalities (ie, cardiac and extracardiac ultrasound), and invasive techniques that might help clinicians to identify different congestion profiles and guide the management strategy in this diverse population of high-risk patients with heart failure.
AB - Congestion plays a major role in the pathogenesis, presentation, and prognosis of heart failure and is an important therapeutic target. However, its severity and organ and compartment distribution vary widely among patients, illustrating the complexity of this phenomenon. Although clinical symptoms and signs are useful to assess congestion and manage volume status in individual patients, they have limited sensitivity and do not allow identification of congestion phenotype. This leads to diagnostic uncertainty and hampers therapeutic decision-making. The present article provides an updated overview of circulating biomarkers, imaging modalities (ie, cardiac and extracardiac ultrasound), and invasive techniques that might help clinicians to identify different congestion profiles and guide the management strategy in this diverse population of high-risk patients with heart failure.
KW - Biomarcadores
KW - Biomarkers
KW - Congestion
KW - Congestión
KW - Medicina de precisión
KW - POCUS
KW - Precision medicine
UR - http://www.scopus.com/inward/record.url?scp=85139861791&partnerID=8YFLogxK
U2 - 10.1016/j.recesp.2022.08.001
DO - 10.1016/j.recesp.2022.08.001
M3 - Article
C2 - 35934293
VL - 76
SP - 47
EP - 57
JO - Revista Española de Cardiología (English version)
JF - Revista Española de Cardiología (English version)
SN - 1885-5857
IS - 1
ER -