Samenvatting
Introduction Worldwide neck pain is a common health problem with high socio-economic burden. A high percentage of these patients evolves towards chronic symptoms. Efficacy of treatments for these complaints remains variable. In current literature, changes in muscle morphology (muscle fatty infiltration [FI] and cross-sectional area [CSA]) have been reported in neck pain patients. However, only limited cohorts were investigated, so no strong conclusions could be made.
Purpose To compare alterations in muscle FI and CSA in cervical flexor and extensor musculature in a cohort of patients with chronic whiplash-associated disorders (CWAD II), patients with chronic idiopathic neck pain (CINP) and healthy control subjects.
Materials and Methods MRI was used to bilaterally measure MFI and CSA for both cervical flexor and extensor muscles in 118 female subjects (37 CWAD, 46 CINP, 35 healthy pain-free controls; 18-63 years). Also, lean muscle CSA (mCSA) was calculated by adjusting for the amount of FI in CSA. A random intercept model was used to model the distribution of FI, CSA and mCSA across the different groups at different cervical levels.
Results The CWAD group had a significantly larger muscle FI in some extensor (semispinalis and splenius capitis, trapezius, obliquus capitis inferior) and flexor (sternocleidomastoideus) muscles compared to the CINP and/or control group. A significant larger CSA was found in some extensor (levator scapulae, semispinalis capitis, trapezius) and flexor (longus colli, longus capitis, sternocleidomastoideus) muscles in the control group compared to the CINP and/or CWAD group. Results were still significant for mCSA.
Relevance Morphological changes may play a role in the maintenance of pain in CWAD.
Conclusions Significant differences between groups were found in specific flexor and extensor muscles for FI, CSA and mCSA.
Implications It needs to be taken into account that different treatment protocols are possibly needed in CWAD patients compared to CINP patients.
Purpose To compare alterations in muscle FI and CSA in cervical flexor and extensor musculature in a cohort of patients with chronic whiplash-associated disorders (CWAD II), patients with chronic idiopathic neck pain (CINP) and healthy control subjects.
Materials and Methods MRI was used to bilaterally measure MFI and CSA for both cervical flexor and extensor muscles in 118 female subjects (37 CWAD, 46 CINP, 35 healthy pain-free controls; 18-63 years). Also, lean muscle CSA (mCSA) was calculated by adjusting for the amount of FI in CSA. A random intercept model was used to model the distribution of FI, CSA and mCSA across the different groups at different cervical levels.
Results The CWAD group had a significantly larger muscle FI in some extensor (semispinalis and splenius capitis, trapezius, obliquus capitis inferior) and flexor (sternocleidomastoideus) muscles compared to the CINP and/or control group. A significant larger CSA was found in some extensor (levator scapulae, semispinalis capitis, trapezius) and flexor (longus colli, longus capitis, sternocleidomastoideus) muscles in the control group compared to the CINP and/or CWAD group. Results were still significant for mCSA.
Relevance Morphological changes may play a role in the maintenance of pain in CWAD.
Conclusions Significant differences between groups were found in specific flexor and extensor muscles for FI, CSA and mCSA.
Implications It needs to be taken into account that different treatment protocols are possibly needed in CWAD patients compared to CINP patients.
| Originele taal-2 | English |
|---|---|
| Status | Published - 1 dec 2018 |
| Evenement | 9th biennial congress of the Belgian Back Society - Duur: 1 dec 2018 → … |
Conference
| Conference | 9th biennial congress of the Belgian Back Society |
|---|---|
| Periode | 1/12/18 → … |