Clinical utility of coronary CT angiography to guide PCI: a survey among P4 investigators

Nikolaos Stalikas; Frederic Bouisset; Takuya Mizukami; Atomu Tajima; Daniel Munhoz; Kazumaza Ikeda; Jeroen Sonck; Eric Wyffels; Adriaan Wilgenhof; Patricio Astudillo; Daniela Trabattoni; Piero Montorsi; Carlo Zivelonghi; Pierfranscesco Agostoni; Benjamin Scott; Paul Vermeersch; Emanuele Gallinoro; Giovanni Monizzi; Daniele Andreini; Bert Vandeloo; Stijn Lochy; Jean-Francois Argacha; Nicolaj Brejnholt Støttrup; Michael Maeng; Thomas Engstrøm; Ketina Arslani; Niels Thue Olsen; Hirohiko Ando; Tetsuya Amano; Hirofumi Ohashi; Allen Jeremias; Ziad Ali; Evan Shlofmitz; Koshiro Sakai; James C Spratt; Emmanouil S Brilakis; Yader Sandoval; Giulio Stefanini; Alan Bagnall; Ian Purcell; István Ferenc Edes; Bernard De Bruyne; Carlos Collet

doi:10.1007/s10554-025-03323-y

Clinical utility of coronary CT angiography to guide PCI: a survey among P4 investigators

Nikolaos Stalikas, Frederic Bouisset, Takuya Mizukami, Atomu Tajima, Daniel Munhoz, Kazumaza Ikeda, Jeroen Sonck, Eric Wyffels, Adriaan Wilgenhof, Patricio Astudillo, Daniela Trabattoni, Piero Montorsi, Carlo Zivelonghi, Pierfranscesco Agostoni, Benjamin Scott, Paul Vermeersch, Emanuele Gallinoro, Giovanni Monizzi, Daniele Andreini, Bert VandelooStijn Lochy, Jean-Francois Argacha, Nicolaj Brejnholt Støttrup, Michael Maeng, Thomas Engstrøm, Ketina Arslani, Niels Thue Olsen, Hirohiko Ando, Tetsuya Amano, Hirofumi Ohashi, Allen Jeremias, Ziad Ali, Evan Shlofmitz, Koshiro Sakai, James C Spratt, Emmanouil S Brilakis, Yader Sandoval, Giulio Stefanini, Alan Bagnall, Ian Purcell, István Ferenc Edes, Bernard De Bruyne, Carlos Collet

Onderzoeksoutput: Article › peer review

Samenvatting

BACKGROUND: Coronary CT Angiography (CTA) is increasingly being used to plan percutaneous coronary intervention (PCI), offering detailed pre-procedural anatomical and physiological insights. The Precise Procedural and PCI Plan (P4) study evaluates the efficacy of CT- versus intravascular ultrasound-guided PCI. The aim of this study was to assess the utility of various CT-guided PCI tools and strategies as perceived by experienced operators within the context of the P4 study.

METHODS: A cross-sectional survey was conducted among 25 operators who participate in the P4 trial from multiple international centers. Participants were asked to evaluate the utility of pre-procedural CTA planning, physiological information with virtual PCI, and online guidance. The survey included multiple-choice, Likert scale, and ranking questions.

RESULTS: Most respondents valued pre-procedural planning highly (average score 2.83/3), particularly for the assessment of plaque composition and calcium characterization. Plaque composition evaluation, including calcium analysis, was ranked as the most valued factor, with an average usefulness score of 6.13/7. Calcium arc information was rated as the most useful component of calcium analysis (4/5 rating). The survey highlighted the importance of myocardial mass at risk assessment in bifurcation PCI and pointed to the anticipation of calcium density as a key future aspect of CT-guided PCI procedures.

CONCLUSIONS: The integration of CT-guided PCI promises to refine procedural planning and to pave the way for a new standard of care in patients with stable CAD.

Originele taal-2	English
Tijdschrift	The International Journal of Cardiovascular Imaging
Vroegere onlinedatum	19 feb. 2025
DOI's	https://doi.org/10.1007/s10554-025-03323-y
Status	E-pub ahead of print - 19 feb. 2025

Bibliografische nota

Publisher Copyright:
© The Author(s), under exclusive licence to Springer Nature B.V. 2025.

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10.1007/s10554-025-03323-y

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Stalikas, N., Bouisset, F., Mizukami, T., Tajima, A., Munhoz, D., Ikeda, K., Sonck, J., Wyffels, E., Wilgenhof, A., Astudillo, P., Trabattoni, D., Montorsi, P., Zivelonghi, C., Agostoni, P., Scott, B., Vermeersch, P., Gallinoro, E., Monizzi, G., Andreini, D., ... Collet, C. (2025). Clinical utility of coronary CT angiography to guide PCI: a survey among P4 investigators. The International Journal of Cardiovascular Imaging. Online publicatie vooraf. https://doi.org/10.1007/s10554-025-03323-y

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title = "Clinical utility of coronary CT angiography to guide PCI: a survey among P4 investigators",

abstract = "BACKGROUND: Coronary CT Angiography (CTA) is increasingly being used to plan percutaneous coronary intervention (PCI), offering detailed pre-procedural anatomical and physiological insights. The Precise Procedural and PCI Plan (P4) study evaluates the efficacy of CT- versus intravascular ultrasound-guided PCI. The aim of this study was to assess the utility of various CT-guided PCI tools and strategies as perceived by experienced operators within the context of the P4 study.METHODS: A cross-sectional survey was conducted among 25 operators who participate in the P4 trial from multiple international centers. Participants were asked to evaluate the utility of pre-procedural CTA planning, physiological information with virtual PCI, and online guidance. The survey included multiple-choice, Likert scale, and ranking questions.RESULTS: Most respondents valued pre-procedural planning highly (average score 2.83/3), particularly for the assessment of plaque composition and calcium characterization. Plaque composition evaluation, including calcium analysis, was ranked as the most valued factor, with an average usefulness score of 6.13/7. Calcium arc information was rated as the most useful component of calcium analysis (4/5 rating). The survey highlighted the importance of myocardial mass at risk assessment in bifurcation PCI and pointed to the anticipation of calcium density as a key future aspect of CT-guided PCI procedures.CONCLUSIONS: The integration of CT-guided PCI promises to refine procedural planning and to pave the way for a new standard of care in patients with stable CAD.",

author = "Nikolaos Stalikas and Frederic Bouisset and Takuya Mizukami and Atomu Tajima and Daniel Munhoz and Kazumaza Ikeda and Jeroen Sonck and Eric Wyffels and Adriaan Wilgenhof and Patricio Astudillo and Daniela Trabattoni and Piero Montorsi and Carlo Zivelonghi and Pierfranscesco Agostoni and Benjamin Scott and Paul Vermeersch and Emanuele Gallinoro and Giovanni Monizzi and Daniele Andreini and Bert Vandeloo and Stijn Lochy and Jean-Francois Argacha and St{\o}ttrup, {Nicolaj Brejnholt} and Michael Maeng and Thomas Engstr{\o}m and Ketina Arslani and Olsen, {Niels Thue} and Hirohiko Ando and Tetsuya Amano and Hirofumi Ohashi and Allen Jeremias and Ziad Ali and Evan Shlofmitz and Koshiro Sakai and Spratt, {James C} and Brilakis, {Emmanouil S} and Yader Sandoval and Giulio Stefanini and Alan Bagnall and Ian Purcell and Edes, {Istv{\'a}n Ferenc} and {De Bruyne}, Bernard and Carlos Collet",

note = "Publisher Copyright: {\textcopyright} The Author(s), under exclusive licence to Springer Nature B.V. 2025.",

year = "2025",

month = feb,

day = "19",

doi = "10.1007/s10554-025-03323-y",

language = "English",

journal = "The International Journal of Cardiovascular Imaging",

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Stalikas, N, Bouisset, F, Mizukami, T, Tajima, A, Munhoz, D, Ikeda, K, Sonck, J, Wyffels, E, Wilgenhof, A, Astudillo, P, Trabattoni, D, Montorsi, P, Zivelonghi, C, Agostoni, P, Scott, B, Vermeersch, P, Gallinoro, E, Monizzi, G, Andreini, D, Vandeloo, B , Lochy, S , Argacha, J-F, Støttrup, NB, Maeng, M, Engstrøm, T, Arslani, K, Olsen, NT, Ando, H, Amano, T, Ohashi, H, Jeremias, A, Ali, Z, Shlofmitz, E, Sakai, K, Spratt, JC, Brilakis, ES, Sandoval, Y, Stefanini, G, Bagnall, A, Purcell, I, Edes, IF, De Bruyne, B & Collet, C 2025, 'Clinical utility of coronary CT angiography to guide PCI: a survey among P4 investigators', The International Journal of Cardiovascular Imaging. https://doi.org/10.1007/s10554-025-03323-y

TY - JOUR

T1 - Clinical utility of coronary CT angiography to guide PCI

T2 - a survey among P4 investigators

AU - Stalikas, Nikolaos

AU - Bouisset, Frederic

AU - Mizukami, Takuya

AU - Tajima, Atomu

AU - Munhoz, Daniel

AU - Ikeda, Kazumaza

AU - Sonck, Jeroen

AU - Wyffels, Eric

AU - Wilgenhof, Adriaan

AU - Astudillo, Patricio

AU - Trabattoni, Daniela

AU - Montorsi, Piero

AU - Zivelonghi, Carlo

AU - Agostoni, Pierfranscesco

AU - Scott, Benjamin

AU - Vermeersch, Paul

AU - Gallinoro, Emanuele

AU - Monizzi, Giovanni

AU - Andreini, Daniele

AU - Vandeloo, Bert

AU - Lochy, Stijn

AU - Argacha, Jean-Francois

AU - Støttrup, Nicolaj Brejnholt

AU - Maeng, Michael

AU - Engstrøm, Thomas

AU - Arslani, Ketina

AU - Olsen, Niels Thue

AU - Ando, Hirohiko

AU - Amano, Tetsuya

AU - Ohashi, Hirofumi

AU - Jeremias, Allen

AU - Ali, Ziad

AU - Shlofmitz, Evan

AU - Sakai, Koshiro

AU - Spratt, James C

AU - Brilakis, Emmanouil S

AU - Sandoval, Yader

AU - Stefanini, Giulio

AU - Bagnall, Alan

AU - Purcell, Ian

AU - Edes, István Ferenc

AU - De Bruyne, Bernard

AU - Collet, Carlos

PY - 2025/2/19

Y1 - 2025/2/19

N2 - BACKGROUND: Coronary CT Angiography (CTA) is increasingly being used to plan percutaneous coronary intervention (PCI), offering detailed pre-procedural anatomical and physiological insights. The Precise Procedural and PCI Plan (P4) study evaluates the efficacy of CT- versus intravascular ultrasound-guided PCI. The aim of this study was to assess the utility of various CT-guided PCI tools and strategies as perceived by experienced operators within the context of the P4 study.METHODS: A cross-sectional survey was conducted among 25 operators who participate in the P4 trial from multiple international centers. Participants were asked to evaluate the utility of pre-procedural CTA planning, physiological information with virtual PCI, and online guidance. The survey included multiple-choice, Likert scale, and ranking questions.RESULTS: Most respondents valued pre-procedural planning highly (average score 2.83/3), particularly for the assessment of plaque composition and calcium characterization. Plaque composition evaluation, including calcium analysis, was ranked as the most valued factor, with an average usefulness score of 6.13/7. Calcium arc information was rated as the most useful component of calcium analysis (4/5 rating). The survey highlighted the importance of myocardial mass at risk assessment in bifurcation PCI and pointed to the anticipation of calcium density as a key future aspect of CT-guided PCI procedures.CONCLUSIONS: The integration of CT-guided PCI promises to refine procedural planning and to pave the way for a new standard of care in patients with stable CAD.

AB - BACKGROUND: Coronary CT Angiography (CTA) is increasingly being used to plan percutaneous coronary intervention (PCI), offering detailed pre-procedural anatomical and physiological insights. The Precise Procedural and PCI Plan (P4) study evaluates the efficacy of CT- versus intravascular ultrasound-guided PCI. The aim of this study was to assess the utility of various CT-guided PCI tools and strategies as perceived by experienced operators within the context of the P4 study.METHODS: A cross-sectional survey was conducted among 25 operators who participate in the P4 trial from multiple international centers. Participants were asked to evaluate the utility of pre-procedural CTA planning, physiological information with virtual PCI, and online guidance. The survey included multiple-choice, Likert scale, and ranking questions.RESULTS: Most respondents valued pre-procedural planning highly (average score 2.83/3), particularly for the assessment of plaque composition and calcium characterization. Plaque composition evaluation, including calcium analysis, was ranked as the most valued factor, with an average usefulness score of 6.13/7. Calcium arc information was rated as the most useful component of calcium analysis (4/5 rating). The survey highlighted the importance of myocardial mass at risk assessment in bifurcation PCI and pointed to the anticipation of calcium density as a key future aspect of CT-guided PCI procedures.CONCLUSIONS: The integration of CT-guided PCI promises to refine procedural planning and to pave the way for a new standard of care in patients with stable CAD.

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U2 - 10.1007/s10554-025-03323-y

DO - 10.1007/s10554-025-03323-y

M3 - Article

C2 - 39971841

SN - 1569-5794

JO - The International Journal of Cardiovascular Imaging

JF - The International Journal of Cardiovascular Imaging

ER -