CS1-specific single-domain antibodies labeled with Actinium-225 prolong survival and increase CD8+ T cells and PD-L1 expression in Multiple Myeloma

Kim De Veirman, Janik Puttemans, Ahmet Krasniqi, Thomas Ertveldt, Heleen Hanssens, Ema Romao, Dirk Hose, Cleo Goyvaert, Philip Vlummens, Serge Muyldermans, Karine Breckpot, Frank Bruchertseifer, Alfred Morgenstern, Matthias D'Huyvetter, Nick Devoogdt

Onderzoeksoutput: Article › peer review

16 Citaten (Scopus)

40 Downloads (Pure)

1 Actief
5 Afgelopen

6 resultaten

Actief
SRP50: SRP-Onderzoekszwaartepunt: Exploiting Peptides: Protein Binders, Modulators and Inhibitors for Imaging and Therapy [Exploit-PeptIT]
Ballet, S., Caveliers, V., Hernot, S., Versées, W., Vinken, M., Muyldermans, S., Devoogdt, N., Bridoux, J. & Martin, C.
1/03/19 → 30/09/25
Project: Fundamenteel
Afgelopen
FWOAL963: Evaluatie van een anti-idiotype NanoCAR-T cel benadering voor de behandeling van Multiple Myeloom
Devoogdt, N., De Veirman, K. & Vandekerckhove, B.
1/01/20 → 31/12/23
Project: Fundamenteel
FWOSB80: Combineren van gerichte radionuclide therapie en kanker immuun therapie om precisie geneeskunde te bevorderen door innovatie.
Breckpot, K., Devoogdt, N., D'Huyvetter, M., Keyaerts, M. & Ertveldt, T.
1/11/19 → 31/10/23
Project: Fundamenteel
SRP62: SRP-Groeifinanciering: Single-domain antibody fragment (SdAb)-based TArgeted Radionuclide Therapy: STaRT programme
Keyaerts, M., D'Huyvetter, M. & Neyns, B.
1/03/19 → 30/09/24
Project: Fundamenteel
SRP48: Strategic Research Programme: Cancer Cell Targeting in Myeloma and Melanoma (MyMe)
Vanderkerken, K., Thielemans, K., Vanderkerken, K. & Breckpot, K.
1/11/17 → 31/10/24
Project: Fundamenteel
ANI184: Nanobody-targeted radionuclide therapy and immune therapy: a perfect match in the area of combination therapy.
Breckpot, K. & Keyaerts, M.
1/01/17 → 31/12/21
Project: Fundamenteel