Diabetes mellitus is a predictor for early adverse outcome in carotid endarterectomy

Erik Debing; Dimitri Aerden; Pierre Van Den Brande

Diabetes mellitus is a predictor for early adverse outcome in carotid endarterectomy

Erik Debing, Dimitri Aerden, Pierre Van Den Brande

Onderzoeksoutput: Article › peer review

15 Citaten (Scopus)

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Abstract
PURPOSE: The aim of the study was to compare the outcome after carotid endarterectomy (CEA) in patients with and without diabetes mellitus.

METHODS: We prospectively recorded the data from patients who underwent CEA. A patient was considered diabetic when he reported the use of antidiabetic medication. De novo diagnosis of diabetes was defined as the first demonstration of a fasting glucose serum concentration >126 mg/dL or >200 mg/dL after glucose load. An early adverse outcome was defined as the occurrence of ipsilateral minor or major stroke and/or death during the 30-day postoperative period.

RESULTS: The stroke and death rate was significantly higher in diabetic patients (n = 380) compared to the controls (n = 971; 4.5% versus 1.5%, P = .002). Multivariate analysis showed a significant association between the presence of diabetes and 30-day stroke and death rate (OR 2.94, CI 1.46-5.97, P = .003).

CONCLUSIONS: Diabetic patients are at greater risk for perioperative stroke and death.

Originele taal-2	English
Pagina's (van-tot)	28-32
Aantal pagina's	5
Tijdschrift	Vascular and Endovascular Surgery
Volume	45
Nummer van het tijdschrift	1
Status	Published - jan 2011

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title = "Diabetes mellitus is a predictor for early adverse outcome in carotid endarterectomy",

abstract = "Abstract PURPOSE: The aim of the study was to compare the outcome after carotid endarterectomy (CEA) in patients with and without diabetes mellitus. METHODS: We prospectively recorded the data from patients who underwent CEA. A patient was considered diabetic when he reported the use of antidiabetic medication. De novo diagnosis of diabetes was defined as the first demonstration of a fasting glucose serum concentration >126 mg/dL or >200 mg/dL after glucose load. An early adverse outcome was defined as the occurrence of ipsilateral minor or major stroke and/or death during the 30-day postoperative period. RESULTS: The stroke and death rate was significantly higher in diabetic patients (n = 380) compared to the controls (n = 971; 4.5% versus 1.5%, P = .002). Multivariate analysis showed a significant association between the presence of diabetes and 30-day stroke and death rate (OR 2.94, CI 1.46-5.97, P = .003). CONCLUSIONS: Diabetic patients are at greater risk for perioperative stroke and death.",

keywords = "diabetes mellitus, carotid endarterectomy",

author = "Erik Debing and Dimitri Aerden and {Van Den Brande}, Pierre",

year = "2011",

month = jan,

language = "English",

volume = "45",

pages = "28--32",

journal = "Vascular and Endovascular Surgery",

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T1 - Diabetes mellitus is a predictor for early adverse outcome in carotid endarterectomy

AU - Debing, Erik

AU - Aerden, Dimitri

AU - Van Den Brande, Pierre

PY - 2011/1

Y1 - 2011/1

N2 - Abstract PURPOSE: The aim of the study was to compare the outcome after carotid endarterectomy (CEA) in patients with and without diabetes mellitus. METHODS: We prospectively recorded the data from patients who underwent CEA. A patient was considered diabetic when he reported the use of antidiabetic medication. De novo diagnosis of diabetes was defined as the first demonstration of a fasting glucose serum concentration >126 mg/dL or >200 mg/dL after glucose load. An early adverse outcome was defined as the occurrence of ipsilateral minor or major stroke and/or death during the 30-day postoperative period. RESULTS: The stroke and death rate was significantly higher in diabetic patients (n = 380) compared to the controls (n = 971; 4.5% versus 1.5%, P = .002). Multivariate analysis showed a significant association between the presence of diabetes and 30-day stroke and death rate (OR 2.94, CI 1.46-5.97, P = .003). CONCLUSIONS: Diabetic patients are at greater risk for perioperative stroke and death.

AB - Abstract PURPOSE: The aim of the study was to compare the outcome after carotid endarterectomy (CEA) in patients with and without diabetes mellitus. METHODS: We prospectively recorded the data from patients who underwent CEA. A patient was considered diabetic when he reported the use of antidiabetic medication. De novo diagnosis of diabetes was defined as the first demonstration of a fasting glucose serum concentration >126 mg/dL or >200 mg/dL after glucose load. An early adverse outcome was defined as the occurrence of ipsilateral minor or major stroke and/or death during the 30-day postoperative period. RESULTS: The stroke and death rate was significantly higher in diabetic patients (n = 380) compared to the controls (n = 971; 4.5% versus 1.5%, P = .002). Multivariate analysis showed a significant association between the presence of diabetes and 30-day stroke and death rate (OR 2.94, CI 1.46-5.97, P = .003). CONCLUSIONS: Diabetic patients are at greater risk for perioperative stroke and death.

KW - diabetes mellitus

KW - carotid endarterectomy

M3 - Article

VL - 45

SP - 28

EP - 32

JO - Vascular and Endovascular Surgery

JF - Vascular and Endovascular Surgery

SN - 1538-5744

IS - 1

ER -

Diabetes mellitus is a predictor for early adverse outcome in carotid endarterectomy

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