Enhancing the T-cell stimulatory capacity of human antigen presenting cells in vitro and in vivo and its use in vaccination

Kris Thielemans; Aude Bonehill

Enhancing the T-cell stimulatory capacity of human antigen presenting cells in vitro and in vivo and its use in vaccination

Kris Thielemans (Uitvinder), Aude Bonehill (Uitvinder)

Onderzoeksoutput: Patent

Samenvatting

We provide new methods of in vitro or in vivo enhancing the T-cell stimulatory capacity of human DCs and the use thereof in cancer vaccination. The method includes the introduction of different molecular adjuvants to human DCs by contacting or modifying them with mRNA or DNA molecule(s) encoding CD40L, and CD70 or constitutively active TLR4 (caTLR4).

Originele taal-2	English
Octrooinummer	US9408909B
Status	Published - 2016

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https://worldwide.espacenet.com/patent/search/family/050148189/publication/US2014056939A1?q=US9408909

IOF242: Financiering IOF-programma vakgroep ETRO (1 en 2)
Stiens, J. (Administrative Promotor), Thielemans, S. (Mandataris), Ersu, B. (Mandataris) & Pourkazemi, A. (Mandataris)
1/01/16 → 31/12/20
Project: Toegepast

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title = "Enhancing the T-cell stimulatory capacity of human antigen presenting cells in vitro and in vivo and its use in vaccination",

abstract = "We provide new methods of in vitro or in vivo enhancing the T-cell stimulatory capacity of human DCs and the use thereof in cancer vaccination. The method includes the introduction of different molecular adjuvants to human DCs by contacting or modifying them with mRNA or DNA molecule(s) encoding CD40L, and CD70 or constitutively active TLR4 (caTLR4).",

author = "Kris Thielemans and Aude Bonehill",

year = "2016",

language = "English",

type = "Patent",

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T1 - Enhancing the T-cell stimulatory capacity of human antigen presenting cells in vitro and in vivo and its use in vaccination

AU - Thielemans, Kris

AU - Bonehill, Aude

PY - 2016

Y1 - 2016

N2 - We provide new methods of in vitro or in vivo enhancing the T-cell stimulatory capacity of human DCs and the use thereof in cancer vaccination. The method includes the introduction of different molecular adjuvants to human DCs by contacting or modifying them with mRNA or DNA molecule(s) encoding CD40L, and CD70 or constitutively active TLR4 (caTLR4).

AB - We provide new methods of in vitro or in vivo enhancing the T-cell stimulatory capacity of human DCs and the use thereof in cancer vaccination. The method includes the introduction of different molecular adjuvants to human DCs by contacting or modifying them with mRNA or DNA molecule(s) encoding CD40L, and CD70 or constitutively active TLR4 (caTLR4).

UR - https://worldwide.espacenet.com/patent/search/family/050148189/publication/US2014056939A1?q=US9408909

M3 - Patent

M1 - US9408909B

ER -

Enhancing the T-cell stimulatory capacity of human antigen presenting cells in vitro and in vivo and its use in vaccination

Samenvatting

Handle.net

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Projecten

IOF242: Financiering IOF-programma vakgroep ETRO (1 en 2)

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