Ethnic variations in fertility history and diabetes mortality: a retrospective cohort study in the Brussels-Capital Region (2001-2005)

Onderzoeksoutput: Meeting abstract (Book)

Samenvatting

Background Women's reproductive histories have been associated with health and mortality in later life. Moreover, reproductive behaviour and diabetes mortality rates vary greatly between ethnic groups. A population-based retrospective cohort study was conducted to establish whether the reproductive factors parity and age at first birth are associated with diabetes mortality and whether these factors contribute to ethnic variations in diabetes mortality among women.

Methods Census data of the Brussels-Capital Region were linked with registration records of all deaths and emigrations between the census date (1 October 2001) and January 2005. The study population consisted of all women aged 45 to 74 of either Belgian or North African origin (N=108,296). To assess the relationships between various reproductive factors and diabetes mortality, Poisson regression models were used. Ethnic variations in diabetes mortality were examined by direct standardization and Poisson regression. Age, educational attainment and household type were included as covariates.

Findings Grandmultiparous women are at increased risk of dying from diabetes. Relative to women with 2 children, women with 4-8 children have a 2.4 times (95% CI 1.6-3.7) higher diabetes mortality rate; in women with 9 children or more the mortality rate ratio (MRR) amounts to 4.6 (95% CI 2.1-10.3). The association between age at first birth and diabetes mortality has an L-shaped pattern, with becoming a mother at age 25-30 presenting the nadir of risk. Age-standardized mortality rates for diabetes as a multiple cause of death are 163.9 (95% CI 139.9-187.8) and 375.4 (95% CI 212.1-538.7) per 100,000 person-years for Belgian and North African women respectively. Taking parity, age at first birth and education into account, the ethnic differences in diabetes mortality largely disappear.

Interpretation Reproductive factors are associated with diabetes mortality and play an important part in the higher diabetes mortality of North African compared with Belgian women.

Funding Research Foundation Flanders (FWO)
Originele taal-2English
TitelUnknown
StatusPublished - 4 sep 2010
EvenementUnknown - Stockholm, Sweden
Duur: 21 sep 200925 sep 2009

Conference

ConferenceUnknown
Land/RegioSweden
StadStockholm
Periode21/09/0925/09/09

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