Freeform beam shaping optics for large-size 3D scaffold fabrication with high accuracy

Onderzoeksoutput: Conference paperResearch


Three-dimensional (3D) bioprinting approaches that enable large-scale constructs and high-resolution simultaneously are
very attractive to tissue engineering applications and health industries. However, both characteristics hardly meet at
reasonable printing times in current 3D bioprinting technologies, affecting the introduction of 3D scaffolds in medical
applications. To overcome this limitation, we recently introduced a vat photopolymerization (VP)-based bioprinting
method named light sheet stereolithography (LS-SLA) and demonstrated the fabrication of centimeter-scale scaffolds with
micrometer-scale features (> 13 μm) by using off-the-shelf optical compounds. The high performance in LS-SLA results
from using a rectangular uniform beam instead of a rotational symmetric laser beam, which generates light sheets with
large length-to-width aspect ratios on the vat film. Beam shaping optics are components used to perform the beam
transformation, and guarantee the accuracy, uniformity, and size of the 3D constructs. This work proposes freeform optics
to perform the laser beam shaping in the LS-SLA device and describes the progress of our investigations from design to
proof-of-concept-demonstrating. The results show that rectangular beams are readily produced by freeform optics resulting
in compact and energy efficient systems, and that further considerations on the real laser output are necessary to deliver
high beam uniformities. Tackling the design challenges of this work leads to energy efficient and high accuracy LS-SLA
Originele taal-2English
TitelOptical Methods for Inspection, Characterization, and Imaging of Biomaterials VI
RedacteurenPietro Ferraro, Demetri Psaltis, Simonetta Grilli
Aantal pagina's9
ISBN van elektronische versie9781510664531
StatusPublished - 11 aug 2023
EvenementSPIE Optical Metrology 2023 - Munich, Germany
Duur: 26 jun 202329 jun 2023

Publicatie series

NaamProceedings of SPIE - The International Society for Optical Engineering
ISSN van geprinte versie0277-786X
ISSN van elektronische versie1996-756X


ConferenceSPIE Optical Metrology 2023

Bibliografische nota

Publisher Copyright:
© 2023 SPIE.


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