Heterogeneity and function of macrophages in the breast during homeostasis and cancer

Eva Hadadi, Sofie Deschoemaeker, Gerard Vicente Venegas, Damya Laoui

Onderzoeksoutput: Chapterpeer review

2 Citaten (Scopus)

Samenvatting

Macrophages are diverse immune cells populating all tissues and adopting a unique tissue-specific identity. Breast macrophages play an essential role in the development and function of the mammary gland over one's lifetime. In the recent years, with the development of fate-mapping, imaging and scRNA-seq technologies we grew a better understanding of the origin, heterogeneity and function of mammary macrophages in homeostasis but also during breast cancer development. Here, we aim to provide a comprehensive review of the latest improvements in studying the macrophage heterogeneity in healthy mammary tissues and breast cancer.
Originele taal-2English
TitelOne, No one, One Hundred Thousand - The Multifaceted Role of Macrophages in Health and Disease - Part A
RedacteurenSamanta A. Mariani, Luca Cassetta, Lorenzo Galluzzi
UitgeverijElsevier
Pagina's149-182
Aantal pagina's34
ISBN van elektronische versie978-0-323-90741-5
ISBN van geprinte versie9780323907415
DOI's
StatusPublished - jan 2022

Publicatie series

NaamInternational Review of Cell and Molecular Biology
Volume367
ISSN van geprinte versie1937-6448

Bibliografische nota

Funding Information:
E.H. is supported by an FWO postdoctoral fellowship, S.D. is supported by a postdoctoral fellowship from Stichting tegen kanker , D.L. is supported by grants from FWO, Kom op Tegen Kanker , Stichting tegen kanker and Vrije Universiteit Brussel .

Publisher Copyright:
© 2022 Elsevier Inc.

Copyright:
Copyright 2023 Elsevier B.V., All rights reserved.

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