Heterogeneity and function of macrophages in the breast during homeostasis and cancer

Eva Hadadi; Sofie Deschoemaeker; Gerard Vicente Venegas; Damya Laoui

doi:10.1016/bs.ircmb.2022.01.002

Heterogeneity and function of macrophages in the breast during homeostasis and cancer

Eva Hadadi, Sofie Deschoemaeker, Gerard Vicente Venegas, Damya Laoui

Onderzoeksoutput: Chapter › Research › peer review

3 Citaten (Scopus)

Samenvatting

Macrophages are diverse immune cells populating all tissues and adopting a unique tissue-specific identity. Breast macrophages play an essential role in the development and function of the mammary gland over one's lifetime. In the recent years, with the development of fate-mapping, imaging and scRNA-seq technologies we grew a better understanding of the origin, heterogeneity and function of mammary macrophages in homeostasis but also during breast cancer development. Here, we aim to provide a comprehensive review of the latest improvements in studying the macrophage heterogeneity in healthy mammary tissues and breast cancer.

Originele taal-2	English
Titel	One, No one, One Hundred Thousand - The Multifaceted Role of Macrophages in Health and Disease - Part A
Redacteuren	Samanta A. Mariani, Luca Cassetta, Lorenzo Galluzzi
Uitgeverij	Elsevier
Pagina's	149-182
Aantal pagina's	34
ISBN van elektronische versie	978-0-323-90741-5
ISBN van geprinte versie	9780323907415
DOI's	https://doi.org/10.1016/bs.ircmb.2022.01.002
Status	Published - jan. 2022

Publicatie series

Naam	International Review of Cell and Molecular Biology
Volume	367
ISSN van geprinte versie	1937-6448

Bibliografische nota

Funding Information:
E.H. is supported by an FWO postdoctoral fellowship, S.D. is supported by a postdoctoral fellowship from Stichting tegen kanker , D.L. is supported by grants from FWO, Kom op Tegen Kanker , Stichting tegen kanker and Vrije Universiteit Brussel .

Publisher Copyright:
© 2022 Elsevier Inc.

Copyright:
Copyright 2023 Elsevier B.V., All rights reserved.

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Hadadi, E., Deschoemaeker, S., Vicente Venegas, G., & Laoui, D. (2022). Heterogeneity and function of macrophages in the breast during homeostasis and cancer. In S. A. Mariani, L. Cassetta, & L. Galluzzi (editors), One, No one, One Hundred Thousand - The Multifaceted Role of Macrophages in Health and Disease - Part A (blz. 149-182). (International Review of Cell and Molecular Biology; Vol. 367). Elsevier. https://doi.org/10.1016/bs.ircmb.2022.01.002

Hadadi, Eva ; Deschoemaeker, Sofie ; Vicente Venegas, Gerard et al. / Heterogeneity and function of macrophages in the breast during homeostasis and cancer. One, No one, One Hundred Thousand - The Multifaceted Role of Macrophages in Health and Disease - Part A. redacteur / Samanta A. Mariani ; Luca Cassetta ; Lorenzo Galluzzi. Elsevier, 2022. blz. 149-182 (International Review of Cell and Molecular Biology).

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title = "Heterogeneity and function of macrophages in the breast during homeostasis and cancer",

abstract = "Macrophages are diverse immune cells populating all tissues and adopting a unique tissue-specific identity. Breast macrophages play an essential role in the development and function of the mammary gland over one's lifetime. In the recent years, with the development of fate-mapping, imaging and scRNA-seq technologies we grew a better understanding of the origin, heterogeneity and function of mammary macrophages in homeostasis but also during breast cancer development. Here, we aim to provide a comprehensive review of the latest improvements in studying the macrophage heterogeneity in healthy mammary tissues and breast cancer.",

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author = "Eva Hadadi and Sofie Deschoemaeker and {Vicente Venegas}, Gerard and Damya Laoui",

note = "Funding Information: E.H. is supported by an FWO postdoctoral fellowship, S.D. is supported by a postdoctoral fellowship from Stichting tegen kanker , D.L. is supported by grants from FWO, Kom op Tegen Kanker , Stichting tegen kanker and Vrije Universiteit Brussel . Publisher Copyright: {\textcopyright} 2022 Elsevier Inc. Copyright: Copyright 2023 Elsevier B.V., All rights reserved.",

year = "2022",

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doi = "10.1016/bs.ircmb.2022.01.002",

language = "English",

isbn = "9780323907415",

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Hadadi, E , Deschoemaeker, S, Vicente Venegas, G & Laoui, D 2022, Heterogeneity and function of macrophages in the breast during homeostasis and cancer. in SA Mariani, L Cassetta & L Galluzzi (uitgave), One, No one, One Hundred Thousand - The Multifaceted Role of Macrophages in Health and Disease - Part A. International Review of Cell and Molecular Biology, vol. 367, Elsevier, blz. 149-182. https://doi.org/10.1016/bs.ircmb.2022.01.002

Heterogeneity and function of macrophages in the breast during homeostasis and cancer. / Hadadi, Eva ; Deschoemaeker, Sofie; Vicente Venegas, Gerard et al.
One, No one, One Hundred Thousand - The Multifaceted Role of Macrophages in Health and Disease - Part A. uitgave / Samanta A. Mariani; Luca Cassetta; Lorenzo Galluzzi. Elsevier, 2022. blz. 149-182 (International Review of Cell and Molecular Biology; Vol. 367).

Onderzoeksoutput: Chapter › Research › peer review

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T1 - Heterogeneity and function of macrophages in the breast during homeostasis and cancer

AU - Hadadi, Eva

AU - Deschoemaeker, Sofie

AU - Vicente Venegas, Gerard

AU - Laoui, Damya

N1 - Funding Information: E.H. is supported by an FWO postdoctoral fellowship, S.D. is supported by a postdoctoral fellowship from Stichting tegen kanker , D.L. is supported by grants from FWO, Kom op Tegen Kanker , Stichting tegen kanker and Vrije Universiteit Brussel . Publisher Copyright: © 2022 Elsevier Inc. Copyright: Copyright 2023 Elsevier B.V., All rights reserved.

PY - 2022/1

Y1 - 2022/1

N2 - Macrophages are diverse immune cells populating all tissues and adopting a unique tissue-specific identity. Breast macrophages play an essential role in the development and function of the mammary gland over one's lifetime. In the recent years, with the development of fate-mapping, imaging and scRNA-seq technologies we grew a better understanding of the origin, heterogeneity and function of mammary macrophages in homeostasis but also during breast cancer development. Here, we aim to provide a comprehensive review of the latest improvements in studying the macrophage heterogeneity in healthy mammary tissues and breast cancer.

AB - Macrophages are diverse immune cells populating all tissues and adopting a unique tissue-specific identity. Breast macrophages play an essential role in the development and function of the mammary gland over one's lifetime. In the recent years, with the development of fate-mapping, imaging and scRNA-seq technologies we grew a better understanding of the origin, heterogeneity and function of mammary macrophages in homeostasis but also during breast cancer development. Here, we aim to provide a comprehensive review of the latest improvements in studying the macrophage heterogeneity in healthy mammary tissues and breast cancer.

KW - MacrophagesBreast cancerTumor-associated macrophagesMammary glandHypoxia

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BT - One, No one, One Hundred Thousand - The Multifaceted Role of Macrophages in Health and Disease - Part A

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Hadadi E , Deschoemaeker S, Vicente Venegas G, Laoui D. Heterogeneity and function of macrophages in the breast during homeostasis and cancer. In Mariani SA, Cassetta L, Galluzzi L, redacteurs, One, No one, One Hundred Thousand - The Multifaceted Role of Macrophages in Health and Disease - Part A. Elsevier. 2022. blz. 149-182. (International Review of Cell and Molecular Biology). doi: 10.1016/bs.ircmb.2022.01.002

Heterogeneity and function of macrophages in the breast during homeostasis and cancer

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