TY - JOUR
T1 - Hormonal causes of recurrent pregnancy loss (RPL)
AU - Pluchino, Nicola
AU - Drakopoulos, Panagiotis
AU - Wenger, Jean Marie
AU - Petignat, Patrick
AU - Streuli, Isabelle
AU - Genazzani, Andrea Riccardo
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Endocrine disorders play a major role in approximately 8% to 12% of recurrent pregnancy loss (RPL). Indeed, the local hormonal milieu is crucial in both embryo attachment and early pregnancy. Endocrine abnormalities, including thyroid disorders, luteal phase defects, polycystic ovary syndrome, hyperprolactinaemia and diabetes have to be evaluated in any case of RPL. Moreover, elevated androgen levels and some endocrinological aspects of endometriosis are also factors contributing to RPL. In the present article, we review the significance of endocrine disease on RPL.
AB - Endocrine disorders play a major role in approximately 8% to 12% of recurrent pregnancy loss (RPL). Indeed, the local hormonal milieu is crucial in both embryo attachment and early pregnancy. Endocrine abnormalities, including thyroid disorders, luteal phase defects, polycystic ovary syndrome, hyperprolactinaemia and diabetes have to be evaluated in any case of RPL. Moreover, elevated androgen levels and some endocrinological aspects of endometriosis are also factors contributing to RPL. In the present article, we review the significance of endocrine disease on RPL.
KW - Abortion
KW - Hyperprolactinaemia
KW - Luteal phase defect
KW - Miscarriage
KW - Recurrent pregnancy loss
UR - http://www.scopus.com/inward/record.url?scp=84904559642&partnerID=8YFLogxK
U2 - 10.14310/horm.2002.1505
DO - 10.14310/horm.2002.1505
M3 - Scientific review
C2 - 25079455
AN - SCOPUS:84904559642
SN - 1109-3099
VL - 13
SP - 314
EP - 322
JO - Hormones
JF - Hormones
IS - 3
ER -