Impact of Sleep Fragmentation on Cognition and Fatigue

Oumaïma Benkirane, Bérénice Delwiche, Olivier Mairesse, Philippe Peigneux

Onderzoeksoutput: Articlepeer review

20 Citaten (Scopus)

Samenvatting

Sleep continuity and efficacy are essential for optimal cognitive functions. How sleep fragmentation (SF) impairs cognitive functioning, and especially cognitive fatigue (CF), remains elusive. We investigated the impact of induced SF on CF through the TloadDback task, measuring interindividual variability in working memory capacity. Sixteen participants underwent an adaptation polysomnography night and three consecutive nights, once in a SF condition induced by non-awakening auditory stimulations, once under restorative sleep (RS) condition, counterbalanced within-subject. In both conditions, participants were administered memory, vigilance, inhibition and verbal fluency testing, and for CF the TloadDback, as well as sleep questionnaires and fatigue and sleepiness visual analog scales were administered. Subjective fatigue increased and sleep architecture was altered after SF (reduced sleep efficiency, percentage of N3 and REM, number of NREM and REM phases) despite similar total sleep time. At the behavioral level, only inhibition deteriorated after SF, and CF similarly evolved in RS and SF conditions. In line with prior research, we show that SF disrupts sleep architecture and exerts a deleterious impact on subjective fatigue and inhibition. However, young healthy participants appear able to compensate for CF induced by three consecutive SF nights. Further studies should investigate SF effects in extended and/or pathological disruption settings.

Originele taal-2English
Artikelnummer15485
Pagina's (van-tot)1-20
Aantal pagina's20
TijdschriftInternational Journal of Environmental Research and Public Health
Volume19
Nummer van het tijdschrift23
DOI's
StatusPublished - 22 nov 2022

Bibliografische nota

Funding Information:
This research was funded by the Fonds de la Recherche Scientifique (FNRS), grant number FC27533.

Publisher Copyright:
© 2022 by the authors.

Copyright:
Copyright 2023 Elsevier B.V., All rights reserved.

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