Is twice daily LF-rTMS a viable treatment option for treatment-resistant OCD? Results from an open-label feasibility study: Results from an open-label feasibility study

Hannelore Tandt, Nele Van de Velde, Sara De Witte, Kurt Audenaert, Chris Baeken, Gilbert Lemmens

Onderzoeksoutput: Articlepeer review

7 Citaten (Scopus)

Samenvatting

Several reports point to the beneficial effects of repetitive transcranial magnetic stimulation (rTMS) in the treatment of resistant obsessive-compulsive disorder (OCD). This study aimed to evaluate the safety and efficacy of rTMS targeting the dmPFC in the treatment of treatment-resistant OCD patients. Twelve patients received 20 sessions of low-frequency (LF) rTMS (1 Hz, 1200 pulses) in a twice daily protocol during 10 weekdays. Y-BOCS and IDS scores modestly but significantly decreased after treatment and at follow-up and HADS anxiety improved at follow-up. LF rTMS may improve OCD, anxiety, and depressive symptoms in treatment-resistant OCD and was a safe and well-tolerated treatment.

Originele taal-2English
Pagina's (van-tot)211-214
Aantal pagina's4
TijdschriftEuropean Archives of Psychiatry and Clinical Neuroscience
Volume271
Nummer van het tijdschrift1
Vroegere onlinedatum2020
DOI's
StatusPublished - feb 2021

Bibliografische nota

Funding Information:
CB and SdW were funded by a Concerted Research Action of Ghent University, Grant/Award Number: BOF16/GOA/017, an Applied Biomedical (TBM) grant of the Agency for Innovation through Science and Technology (IWT), part of the Research Foundation–Flanders (FWO), awarded to the PrevenD project (B/14730/01), and het Fonds Wetenschappelijk Onderzoek Rode Neuzen, Grant/Award Number: G0F4617N.

Publisher Copyright:
© 2020, Springer-Verlag GmbH Germany, part of Springer Nature.

Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.

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