Left ventricular rotational mechanics in patients with coronary artery disease: differences in subendocardial and subepicardial layers.

Victoria Delgado; Matteo Bertini; Gaetano Nucifora; Nina Ajmone Marsan; Arnold Ng; Miriam Shanks; Louisa Antoni; Nico Van De Veire; Rutger Van Bommel; C Rapezzi; Martin Schalij; Jeroen Bax

Left ventricular rotational mechanics in patients with coronary artery disease: differences in subendocardial and subepicardial layers.

Victoria Delgado, Matteo Bertini, Gaetano Nucifora, Nina Ajmone Marsan, Arnold Ng, Miriam Shanks, Louisa Antoni, Nico Van De Veire, Rutger Van Bommel, C Rapezzi, Martin Schalij, Jeroen Bax

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Onderzoeksoutput: Article › peer review

33 Citaten (Scopus)

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OBJECTIVE: Subendocardial and subepicardial layers have opposite orientation of the myofibres and they are differently affected by coronary artery disease. This study investigated the differences in subendocardial and subepicardial left ventricular (LV) twist in patients with coronary artery disease.

METHODS: 214 patients were included in the study: 60 with first ST elevation myocardial infarction (STEMI), 111 with chronic ischaemic heart failure (HF) and 43 normal subjects. Real-time three-dimensional echocardiography provided LV volumes and function. Two-dimensional speckle tracking echocardiography differentiating the subendocardial and subepicardial layers was used for the assessment of LV twist. Patients with STEMI were divided into two groups (small and large STEMI).

RESULTS: Compared with normal subjects, peak subendocardial LV twist was significantly impaired in patients with STEMI (11.2 ± 6.0° vs 15.3 ± 2.7°, p
CONCLUSIONS: Subendocardial LV twist is reduced in patients with STEMI and chronic ischaemic HF whereas subepicardial LV twist is reduced only in chronic ischaemic HF. When STEMI are divided into large and small infarctions, it becomes evident that subepicardial LV twist is only reduced in large infarctions.

Originele taal-2	English
Pagina's (van-tot)	1737-1743
Aantal pagina's	7
Tijdschrift	Heart
Volume	96
Nummer van het tijdschrift	21
Status	Published - 1 nov. 2010

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@article{a70e3b6a477e479abcf6e5257f7574d9,

title = "Left ventricular rotational mechanics in patients with coronary artery disease: differences in subendocardial and subepicardial layers.",

abstract = "OBJECTIVE: Subendocardial and subepicardial layers have opposite orientation of the myofibres and they are differently affected by coronary artery disease. This study investigated the differences in subendocardial and subepicardial left ventricular (LV) twist in patients with coronary artery disease. METHODS: 214 patients were included in the study: 60 with first ST elevation myocardial infarction (STEMI), 111 with chronic ischaemic heart failure (HF) and 43 normal subjects. Real-time three-dimensional echocardiography provided LV volumes and function. Two-dimensional speckle tracking echocardiography differentiating the subendocardial and subepicardial layers was used for the assessment of LV twist. Patients with STEMI were divided into two groups (small and large STEMI). RESULTS: Compared with normal subjects, peak subendocardial LV twist was significantly impaired in patients with STEMI (11.2 ± 6.0° vs 15.3 ± 2.7°, p CONCLUSIONS: Subendocardial LV twist is reduced in patients with STEMI and chronic ischaemic HF whereas subepicardial LV twist is reduced only in chronic ischaemic HF. When STEMI are divided into large and small infarctions, it becomes evident that subepicardial LV twist is only reduced in large infarctions.",

keywords = "echocardiography, TIME 3-DIMENSIONAL ECHOCARDIOGRAPHY, ACUTE MYOCARDIAL-INFARCTION, CARDIAC MAGNETIC-RESONANCE",

author = "Victoria Delgado and Matteo Bertini and Gaetano Nucifora and {Ajmone Marsan}, Nina and Arnold Ng and Miriam Shanks and Louisa Antoni and {Van De Veire}, Nico and {Van Bommel}, Rutger and C Rapezzi and Martin Schalij and Jeroen Bax",

year = "2010",

month = nov,

day = "1",

language = "English",

volume = "96",

pages = "1737--1743",

journal = "Heart",

issn = "1355-6037",

publisher = "BMJ Publishing Group",

number = "21",

}

TY - JOUR

T1 - Left ventricular rotational mechanics in patients with coronary artery disease: differences in subendocardial and subepicardial layers.

AU - Delgado, Victoria

AU - Bertini, Matteo

AU - Nucifora, Gaetano

AU - Ajmone Marsan, Nina

AU - Ng, Arnold

AU - Shanks, Miriam

AU - Antoni, Louisa

AU - Van De Veire, Nico

AU - Van Bommel, Rutger

AU - Rapezzi, C

AU - Schalij, Martin

AU - Bax, Jeroen

PY - 2010/11/1

Y1 - 2010/11/1

N2 - OBJECTIVE: Subendocardial and subepicardial layers have opposite orientation of the myofibres and they are differently affected by coronary artery disease. This study investigated the differences in subendocardial and subepicardial left ventricular (LV) twist in patients with coronary artery disease. METHODS: 214 patients were included in the study: 60 with first ST elevation myocardial infarction (STEMI), 111 with chronic ischaemic heart failure (HF) and 43 normal subjects. Real-time three-dimensional echocardiography provided LV volumes and function. Two-dimensional speckle tracking echocardiography differentiating the subendocardial and subepicardial layers was used for the assessment of LV twist. Patients with STEMI were divided into two groups (small and large STEMI). RESULTS: Compared with normal subjects, peak subendocardial LV twist was significantly impaired in patients with STEMI (11.2 ± 6.0° vs 15.3 ± 2.7°, p CONCLUSIONS: Subendocardial LV twist is reduced in patients with STEMI and chronic ischaemic HF whereas subepicardial LV twist is reduced only in chronic ischaemic HF. When STEMI are divided into large and small infarctions, it becomes evident that subepicardial LV twist is only reduced in large infarctions.

AB - OBJECTIVE: Subendocardial and subepicardial layers have opposite orientation of the myofibres and they are differently affected by coronary artery disease. This study investigated the differences in subendocardial and subepicardial left ventricular (LV) twist in patients with coronary artery disease. METHODS: 214 patients were included in the study: 60 with first ST elevation myocardial infarction (STEMI), 111 with chronic ischaemic heart failure (HF) and 43 normal subjects. Real-time three-dimensional echocardiography provided LV volumes and function. Two-dimensional speckle tracking echocardiography differentiating the subendocardial and subepicardial layers was used for the assessment of LV twist. Patients with STEMI were divided into two groups (small and large STEMI). RESULTS: Compared with normal subjects, peak subendocardial LV twist was significantly impaired in patients with STEMI (11.2 ± 6.0° vs 15.3 ± 2.7°, p CONCLUSIONS: Subendocardial LV twist is reduced in patients with STEMI and chronic ischaemic HF whereas subepicardial LV twist is reduced only in chronic ischaemic HF. When STEMI are divided into large and small infarctions, it becomes evident that subepicardial LV twist is only reduced in large infarctions.

KW - echocardiography

KW - TIME 3-DIMENSIONAL ECHOCARDIOGRAPHY

KW - ACUTE MYOCARDIAL-INFARCTION

KW - CARDIAC MAGNETIC-RESONANCE

M3 - Article

SN - 1355-6037

VL - 96

SP - 1737

EP - 1743

JO - Heart

JF - Heart

IS - 21

ER -

Left ventricular rotational mechanics in patients with coronary artery disease: differences in subendocardial and subepicardial layers.

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