Metal-organic frameworks as stationary phases for chiral chromatographic and membrane separations

Nowadays thousands of stable MOF structures are known and investigated for guest-host adsorption in liquid and gas phase. Here, in this review, we focus on the current state-of-art regarding chiral resolution using homochiral MOF structures. Synthesis routes and pore architectures are critically reviewed along with the reported chiral resolution potential for small chiral organics. Besides gas and liquid phase adsorption of racemates, special attention is given to the application of these materials as stationary phases (GC, HPLC) and their use in membrane applications.