MICA is associated with type 1 diabetes in the Belgian population, independent of HLA-DQ

Jan Van Autreve; Bobby Koeleman; Erik Quartier; Folefac Aminkeng; Bart Van Der Auwera; Ilse Weets; Frans Gorus

MICA is associated with type 1 diabetes in the Belgian population, independent of HLA-DQ

Jan Van Autreve
, Bobby Koeleman
, Erik Quartier
, Folefac Aminkeng
, Bart Van Der Auwera
, Ilse Weets
, Frans Gorus

Onderzoeksoutput: Article › peer review

14 Citaten (Scopus)

Samenvatting

To ascertain association of MICA with type 1 diabetes (T1D) in the Belgian population, well-characterized antibody-positive patients were analyzed for MICA transmembrane gene polymorphism in both an association study and a nuclear family study. The frequency of MICAS was significantly increased in the T1D patient group (18%) compared with the control population (12%, OR = 1.6, pc <10-3), whereas MICA9 was decreased (11% versus 16%, OR = 0.7, pc <0.01). A p value

Originele taal-2	English
Pagina's (van-tot)	94-101
Aantal pagina's	8
Tijdschrift	Human Immunology
Volume	67
Status	Published - 2006

Bibliografische nota

Human Immunology 67:94-101, 2006

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Permanente koppeling

Lecture: Functional genetics of type 1 diabetes
Van Der Auwera, B. (Member)
26 nov. 2004
Activiteit: Types of External academic engagement - Hosting an academic visitor

Citeer dit

@article{9277596db6024241bc0ecfcbeb5ad0cd,

title = "MICA is associated with type 1 diabetes in the Belgian population, independent of HLA-DQ",

abstract = "To ascertain association of MICA with type 1 diabetes (T1D) in the Belgian population, well-characterized antibody-positive patients were analyzed for MICA transmembrane gene polymorphism in both an association study and a nuclear family study. The frequency of MICAS was significantly increased in the T1D patient group (18\%) compared with the control population (12\%, OR = 1.6, pc <10-3), whereas MICA9 was decreased (11\% versus 16\%, OR = 0.7, pc <0.01). A p value",

keywords = "MICA, HLA, risk, type 1 diabetes",

author = "\{Van Autreve\}, Jan and Bobby Koeleman and Erik Quartier and Folefac Aminkeng and \{Van Der Auwera\}, Bart and Ilse Weets and Frans Gorus",

note = "Human Immunology 67:94-101, 2006",

year = "2006",

language = "English",

volume = "67",

pages = "94--101",

journal = "Human Immunology",

issn = "0198-8859",

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TY - JOUR

T1 - MICA is associated with type 1 diabetes in the Belgian population, independent of HLA-DQ

AU - Van Autreve, Jan

AU - Koeleman, Bobby

AU - Quartier, Erik

AU - Aminkeng, Folefac

AU - Van Der Auwera, Bart

AU - Weets, Ilse

AU - Gorus, Frans

N1 - Human Immunology 67:94-101, 2006

PY - 2006

Y1 - 2006

N2 - To ascertain association of MICA with type 1 diabetes (T1D) in the Belgian population, well-characterized antibody-positive patients were analyzed for MICA transmembrane gene polymorphism in both an association study and a nuclear family study. The frequency of MICAS was significantly increased in the T1D patient group (18%) compared with the control population (12%, OR = 1.6, pc <10-3), whereas MICA9 was decreased (11% versus 16%, OR = 0.7, pc <0.01). A p value

AB - To ascertain association of MICA with type 1 diabetes (T1D) in the Belgian population, well-characterized antibody-positive patients were analyzed for MICA transmembrane gene polymorphism in both an association study and a nuclear family study. The frequency of MICAS was significantly increased in the T1D patient group (18%) compared with the control population (12%, OR = 1.6, pc <10-3), whereas MICA9 was decreased (11% versus 16%, OR = 0.7, pc <0.01). A p value

KW - MICA

KW - HLA

KW - risk

KW - type 1 diabetes

M3 - Article

SN - 0198-8859

VL - 67

SP - 94

EP - 101

JO - Human Immunology

JF - Human Immunology

ER -

MICA is associated with type 1 diabetes in the Belgian population, independent of HLA-DQ

Samenvatting

Bibliografische nota

Handle.net

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Activiteiten

Lecture: Functional genetics of type 1 diabetes

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